- ICH GCP
- US-Register für klinische Studien
- Klinische Studie NCT07718009
Effects of Alternating Altitude Training Versus Fixed-Altitude Training on Exercise Capacity and Physiological Adaptations in Elite Race Walkers: A Randomized Controlled Trial
Effects of Alternating Altitude Training Versus Fixed-Altitude Training on Physical Performance and Physiological Adaptations in Elite Race Walkers: A Randomized Controlled Trial
Studienübersicht
Status
Bedingungen
Intervention / Behandlung
Studientyp
Einschreibung (Geschätzt)
Phase
- Unzutreffend
Kontakte und Standorte
Studienkontakt
- Name: Binghong Gao
- Telefonnummer: +853 8591 2000
- E-Mail: research_ethics@ipm.edu.mo
Studienorte
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Macao, China
- Rekrutierung
- Macao Polytechnic University, Faculty of Health Sciences and Sports, Macao, China
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Kontakt:
- Chaoran Han
- Telefonnummer: +853 8591 2000
- E-Mail: hanchaoran1999@outlook.com
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Teilnahmekriterien
Zulassungskriterien
Studienberechtigtes Alter
- Erwachsene
Akzeptiert gesunde Freiwillige
Beschreibung
Inclusion Criteria:
- Male and female elite race walkers aged 16-26 years. Registered athletes from the Yunnan Provincial Race Walking Team. Long-term residents of high-altitude regions with regular altitude training experience.
Healthy and medically cleared to participate in high-intensity training and hypoxic exposure.
Able to complete the prescribed training program and all outcome assessments. Provided written informed consent before enrollment. For participants younger than 18 years, written informed consent will also be obtained from a parent or legal guardian.
Exclusion Criteria:
- Any cardiovascular, respiratory, metabolic, neurological, or other medical condition contraindicating exercise or hypoxic exposure.
Musculoskeletal injury or illness affecting normal training or performance within the previous three months.
Current use of medications or supplements that may substantially influence physiological adaptation or exercise performance.
Failure to complete the intervention or outcome assessments according to the study protocol.
Withdrawal of informed consent at any time during the study.
Studienplan
Wie ist die Studie aufgebaut?
Designdetails
- Hauptzweck: Sonstiges
- Zuteilung: Zufällig
- Interventionsmodell: Parallele Zuordnung
- Maskierung: Keine (Offenes Etikett)
Waffen und Interventionen
Teilnehmergruppe / Arm |
Intervention / Behandlung |
|---|---|
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Experimental: Alternating Altitude Training
Participants perform the prescribed training program using an alternating altitude strategy, with selected training sessions conducted under simulated higher-altitude conditions and the remaining sessions completed at the regular altitude training base.
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Participants complete the prescribed training program using an alternating altitude strategy, combining regular altitude training with selected sessions performed under simulated higher-altitude conditions.
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Aktiver Komparator: Fixed-Altitude Training
Participants perform the same prescribed training program entirely at the regular altitude training base throughout the intervention.
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Participants complete the prescribed training program exclusively at the regular altitude training base.
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Was misst die Studie?
Primäre Ergebnismessungen
Ergebnis Maßnahme |
Maßnahmenbeschreibung |
Zeitfenster |
|---|---|---|
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Body Weight
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Body weight measured before and after the training period.
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Baseline and immediately after completion of the 4-week intervention.
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Body Fat Percentage
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Body fat percentage measured using bioelectrical impedance or other validated method.
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Baseline and immediately after completion of the 4-week intervention.
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Forced Vital Capacity (FVC)
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Forced vital capacity measured using spirometry before and after the intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Maximal Voluntary Ventilation
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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MVV measured using standard pulmonary function testing protocol pre- and post-intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Left Ventricular Volume
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Echocardiography measurement of left ventricular end-diastolic and end-systolic volume.
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Baseline and immediately after completion of the 4-week intervention.
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Ejection Fraction
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Echocardiography assessment of left ventricular ejection fraction pre- and post-training.
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Baseline and immediately after completion of the 4-week intervention.
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Myocardial Thickness
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Measurement of interventricular septum and left ventricular posterior wall thickness by echocardiography.
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Baseline and immediately after completion of the 4-week intervention.
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Maximal Oxygen Uptake
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Pre- and post-intervention measurement of VO₂max using standard exercise testing protocol to assess aerobic capacity
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Baseline and immediately after completion of the 4-week intervention.
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Countermovement Jump Height
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Countermovement jump (CMJ) height measured using a validated force platform or jump assessment system to evaluate lower-limb explosive power before and after the intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Squat Jump Height
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Squat jump (SJ) height measured using a validated force platform or jump assessment system to assess concentric lower-limb explosive strength before and after the intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Isometric Mid-Thigh Pull Peak Force
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Peak force during the isometric mid-thigh pull (IMTP) measured using a force platform to assess maximal isometric lower-limb strength before and after the intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Isometric Mid-Thigh Pull Rate of Force Development
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Rate of force development (RFD) during the isometric mid-thigh pull (IMTP) measured using a force platform before and after the intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Reactive Strength Index (RSI)
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Reactive Strength Index (RSI) calculated from repeated ankle hops using a force platform or validated jump assessment system to assess lower-limb reactive strength before and after the intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Sekundäre Ergebnismessungen
Ergebnis Maßnahme |
Maßnahmenbeschreibung |
Zeitfenster |
|---|---|---|
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Red Blood Cell Count
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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RBC count measured from venous blood samples pre- and post-intervention.
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Baseline and immediately after completion of the 4-week intervention.
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Hemoglobin
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Hemoglobin concentration measured from venous blood samples.
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Baseline and immediately after completion of the 4-week intervention.
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Hematocrit
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Hemoglobin concentration measured from venous blood samples.
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Baseline and immediately after completion of the 4-week intervention.
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Erythropoietin
Zeitfenster: Baseline and immediately after completion of the 4-week intervention.
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Plasma EPO concentration measured from venous blood samples.
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Baseline and immediately after completion of the 4-week intervention.
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Mitarbeiter und Ermittler
Sponsor
Studienaufzeichnungsdaten
Haupttermine studieren
Studienbeginn (Geschätzt)
Primärer Abschluss (Geschätzt)
Studienabschluss (Geschätzt)
Studienanmeldedaten
Zuerst eingereicht
Zuerst eingereicht, das die QC-Kriterien erfüllt hat
Zuerst gepostet (Tatsächlich)
Studienaufzeichnungsaktualisierungen
Letztes Update gepostet (Tatsächlich)
Letztes eingereichtes Update, das die QC-Kriterien erfüllt
Zuletzt verifiziert
Mehr Informationen
Begriffe im Zusammenhang mit dieser Studie
Andere Studien-ID-Nummern
- AAT-RW-2026-01
Plan für individuelle Teilnehmerdaten (IPD)
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