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Carbohydrate-Protein Supplementation During Endurance Running

3 de abril de 2018 actualizado por: Hollie Raynor, The University of Tennessee, Knoxville

"Nutritional Ergogenic Aids: The Effects of Carbohydrate-Protein Supplementation During Endurance Exercise"

The purpose of this study is to assess whether the greater performance benefits from ingesting carbohydrate-protein supplements during endurance running, in comparison to the traditionally used carbohydrate supplement, is attributed to the extra calories contained in the carbohydrate-protein supplement or the presence of protein.

Descripción general del estudio

Descripción detallada

The purpose of this study is to determine whether the performance benefits from consuming a carbohydrate-protein (CHO-P) supplement, such as Accelerade, during endurance exercise, as opposed to the traditionally used carbohydrate (CHO) supplement, such as Gatorade, are attributed to the extra calories in the CHO-P supplement or the presence of protein alone in comparison to CHO supplements. Numerous studies comparing CHO and CHO-P supplements on endurance performance have found contradicting results in terms of CHO-P supplementation and performance benefits. While physiological mechanisms have been proposed as to why the CHO-P supplements elicit greater performance, research has yet to determine why some studies have found this, especially while other studies have found no performance benefits from CHO-P supplementation. This inconsistency in research may be due to the caloric difference between supplements tested; due to the addition of protein, the CHO-P supplement contains more calories per serving than the CHO supplement. As a result, this study will be comparing 4 different supplements during endurance exercise, a CHO-P supplement, CHO supplement, a double carbohydrate supplement (CHO-CHO), and a placebo (PLA). The CHO and CHO-P supplement will be matched for CHO content, whereas the CHO-P and CHO-CHO supplements will be matched for total caloric content. Participants will be asked to run four 12-mile runs on 4 separate occasions, approximately 7-10 days apart, and will be blinded to supplement content and order of supplement administration among trials. The 12-mile run will elicit an exercise bout greater than 60 minutes, which is relevant when supplementing exercise with CHO or CHO-P. Performance will be assessed via time it takes to complete both the 12-mile run and the 1.6 mile maximal effort at the end of the run.

Tipo de estudio

Intervencionista

Inscripción (Actual)

12

Fase

  • No aplica

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Ubicaciones de estudio

    • Tennessee
      • Knoxville, Tennessee, Estados Unidos, 37996
        • Health Physical Education and Recreation Building

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

18 años a 55 años (Adulto)

Acepta Voluntarios Saludables

Sí

Géneros elegibles para el estudio

Masculino

Descripción

Inclusion Criteria:

  • Males aged 18-55 years old
  • BMI in the healthy range, 18.5-24.9
  • Run 45-90+ minutes at least 4 days per week
  • Engage in running this frequency and duration for at least 4 weeks prior to the phone screen
  • Engage in a run consisting ≥10 miles in length for at least 2-4 occasions per month for at least 2 months prior to the phone screen
  • No previous history of heart conditions
  • No shortness of breath or chest pain experienced during running or daily activities
  • No bone or joint problems experienced during running or daily activities

Exclusion Criteria:

  • Females and males under the age of 18 and over the age of 55
  • Females are excluded from this study in order to prevent any potential factors associated with the female athlete triad and endurance performance outcomes.
  • BMI below 18.5 or greater than 24.9
  • Does not meet all other criteria listed (#3-6)
  • Allergies to products containing milk, soy, or aspartame
  • Severe allergies to eggs, wheat, tree nuts, fish, crustaceans, shellfish products (Accelerade, the CHO-P supplement, is made in a facility that processed these products)
  • Refusal to consume any of the supplements, and/or extreme dislike of the supplements
  • Refusal to complete the specified distance of the time trials

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Propósito principal: Otro
  • Asignación: Aleatorizado
  • Modelo Intervencionista: Asignación factorial
  • Enmascaramiento: Único

Armas e Intervenciones

Grupo de participantes/brazo
Intervención / Tratamiento
Comparador activo: Order 1
Supplement order for each time trial run, 1-4 respectively: CHO, CHO-P, CHO-CHO, PLA
The CHO supplement will be administered during trial 1. The CHO-P will be administered during trial 2. The CHO-CHO supplement will be administered during trial 3. The PLA supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.
Comparador activo: Order 2
Supplement order for each time trial run, 1-4 respectively: CHO-P, CHO-CHO, PLA, CHO
The CHO-P supplement will be administered during trial 1. The CHO-CHO will be administered during trial 2. The PLA supplement will be administered during trial 3. The CHO supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.
Comparador activo: Order 3
Supplement order for each time trial run, 1-4 respectively: CHO-CHO, PLA, CHO, CHO-P
The CHO-CHO supplement will be administered during trial 1. The PLA will be administered during trial 2. The CHO supplement will be administered during trial 3. The CHO-P supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.
Comparador activo: Order 4
Supplement order for each time trial run, 1-4 respectively: PLA, CHO, CHO-P, CHO-CHO
The PLA supplement will be administered during trial 1. The CHO will be administered during trial 2. The CHO-P supplement will be administered during trial 3. The CHO-CHO supplement will be administered during trial 4. This is the order of supplement administration for subjects randomly assigned to this order group.

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Periodo de tiempo
Time it takes to complete each 12-mile time trial run
Periodo de tiempo: 4 days
4 days
Time it takes to complete the 1.6 mile maximal effort at the end of the 12 mile run.
Periodo de tiempo: 4 days
4 days

Medidas de resultado secundarias

Medida de resultado
Periodo de tiempo
Heart Rate at the beginning of each time trial, start of the maximal effort, end of the run.
Periodo de tiempo: 4 days
4 days
Rating of perceived exertion through out the duration of the 12 mile time trial run.
Periodo de tiempo: 4 days
4 days

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Investigadores

  • Silla de estudio: Hollie A Raynor, PhD, University of Tennessee, Knoxville

Publicaciones y enlaces útiles

La persona responsable de ingresar información sobre el estudio proporciona voluntariamente estas publicaciones. Estos pueden ser sobre cualquier cosa relacionada con el estudio.

Enlaces Útiles

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio

1 de agosto de 2009

Finalización primaria (Actual)

1 de abril de 2010

Finalización del estudio (Actual)

1 de abril de 2010

Fechas de registro del estudio

Enviado por primera vez

3 de septiembre de 2009

Primero enviado que cumplió con los criterios de control de calidad

3 de septiembre de 2009

Publicado por primera vez (Estimar)

4 de septiembre de 2009

Actualizaciones de registros de estudio

Última actualización publicada (Actual)

5 de abril de 2018

Última actualización enviada que cumplió con los criterios de control de calidad

3 de abril de 2018

Última verificación

1 de abril de 2018

Más información

Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .

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