Effect of Curd Cheese on Metabolic Health in Adults
27 de junio de 2026 actualizado por: Süleyman Kılıç
The Effect of a Diet Intervention Supplemented With Curd Cheese on Anthropometric Measurements, Glycemia, and Lipidemia in Adults Applying to Darıca Healthy Life Center
This randomized controlled trial aims to evaluate the effects of a diet supplemented with curd cheese on anthropometric measurements, glycemia, and lipid profile in overweight adults.
Participants aged 40-64 years with a BMI above 25 will be randomly assigned to an intervention group receiving 100 g of curd cheese at breakfast for 8 weeks or to a control group receiving a standard healthy diet without curd cheese.
Primary outcomes include changes in fasting blood glucose and HbA1c, while secondary outcomes are changes in body composition, waist circumference, and lipid profile (HDL, LDL, triglycerides, total cholesterol).
Descripción general del estudio
Estado
Terminado
Condiciones
Intervención / Tratamiento
Descripción detallada
Metabolic disorders, including obesity, dyslipidemia, and type 2 diabetes mellitus, are major public health concerns worldwide. Dietary protein quality and source have been shown to play important roles in regulating glucose and lipid metabolism. Whey-derived proteins are rich in branched-chain amino acids and bioactive peptides that may enhance insulin sensitivity, promote satiety, and improve lipid profiles.
Curd cheese (lor cheese) is a traditional dairy product obtained during whey processing, characterized by its high-quality protein, low fat content, and rich calcium composition. It represents an affordable and accessible food that could be incorporated into dietary interventions targeting metabolic health improvement.
This study aims to investigate the effects of a curd cheese-supplemented diet on anthropometric parameters, glycemic control (including fasting glucose and HbA1c), and lipid profile (total cholesterol, HDL, LDL, and triglycerides) in adults attending the Darıca Healthy Life Center. Participants will follow a controlled dietary intervention with or without curd cheese for eight weeks.
The hypothesis of this study is that regular consumption of curd cheese as part of a balanced diet may improve metabolic parameters through increased protein intake, better glycemic regulation, and enhanced lipid metabolism.
Tipo de estudio
Intervencionista
Inscripción (Actual)
44
Fase
- No aplica
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Ubicaciones de estudio
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DARICA
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Kocaeli, DARICA, Turquía (Türkiye), 41700
- Darıca Healthy Life Center
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Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
Acepta Voluntarios Saludables
Sí
Descripción
Inclusion Criteria:
- Individuals aged 40-64 years.
- Body Mass Index (BMI) greater than 25 kg/m².
- Individuals who voluntarily applied to the Darıca Healthy Life Center and agreed to participate in the study.
- Individuals who have had HbA1c, glucose, and lipid profile measurements within the past month, or will have these measurements taken as part of this study.
- Individuals who are able to comply with the curd cheese-supplemented dietary intervention for at least 8 weeks.
- Individuals who have signed the written informed consent form.
Exclusion Criteria:
- Individuals diagnosed with diabetes mellitus.
- Individuals with chronic diseases such as renal, hepatic, or cardiac failure.
- Individuals with lactose intolerance or allergy to milk and dairy products.
- Pregnant or lactating women.
- Individuals with restricted protein intake for any medical reason.
- Individuals who have participated in another dietary intervention program within the last 3 months.
- Individuals diagnosed with psychiatric disorders requiring regular treatment.
- Individuals with irregular lifestyles or communication difficulties that may prevent adherence to the dietary intervention.
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Ninguno (etiqueta abierta)
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
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Experimental: Curd Cheese Supplemented Diet Group
Intervention Group - Arm Description: Participants in this arm follow a customized dietary plan for 8 weeks that includes daily servings of curd cheese. The diet is balanced for energy and macronutrient distribution according to individual needs. Curd cheese, as a high-quality protein and calcium source, is included to assess its specific effects on glucose and lipid parameters. This arm is designed to evaluate the unique metabolic effects of curd cheese supplementation compared to the control group. |
This intervention consists of daily consumption of 100 grams of curd cheese as part of a personalized dietary plan for 8 weeks.
Curd cheese is consumed at breakfast and integrated into the participants' regular meal plans.
The diet is balanced for total energy and macronutrient distribution according to individual nutritional needs.
All participants in this arm receive the same type and brand of curd cheese throughout the intervention period.
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Sin intervención: Standard Diet Group
Participants in this arm follow a standard dietary plan for 8 weeks without curd cheese.
The diet is balanced according to individual energy and macronutrient needs.
This arm serves as a comparison group to determine the specific effects of curd cheese supplementation observed in the intervention group.
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
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Change in HbA1c Levels
Periodo de tiempo: Baseline and after 8 weeks of intervention
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To evaluate the effect of a curd cheese-supplemented diet on glycemic control by assessing changes in HbA1c levels from baseline to the end of the 8-week intervention.
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Baseline and after 8 weeks of intervention
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Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Change in Fasting Glucose
Periodo de tiempo: Baseline and after 8 weeks
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To assess short-term glycemic response by measuring fasting blood glucose at baseline and after the 8-week intervention.
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Baseline and after 8 weeks
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Change in Lipid Profile
Periodo de tiempo: Baseline and after 8 weeks
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To evaluate the effect of curd cheese supplementation on lipid metabolism by assessing changes in total cholesterol, LDL, HDL, and triglycerides from baseline to the end of the intervention.
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Baseline and after 8 weeks
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Change in Anthropometric Measures
Periodo de tiempo: Baseline and after 8 weeks
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To evaluate changes in body mass index (BMI) from the start to the end of the intervention.
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Baseline and after 8 weeks
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Change in Anthropometric Measures
Periodo de tiempo: Baseline and after 8 weeks
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To assess changes in body weight from baseline to the end of the intervention.
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Baseline and after 8 weeks
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Change in Anthropometric Measures
Periodo de tiempo: Baseline and after 8 weeks
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To evaluate changes in body fat percentage from the beginning to the end of the intervention.
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Baseline and after 8 weeks
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Change in Anthropometric Measures
Periodo de tiempo: Baseline and after 8 weeks
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To assess changes in waist circumference from the beginning to the end of the intervention.
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Baseline and after 8 weeks
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Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Colaboradores
Investigadores
- Investigador principal: Ahmet M GÜNAL, PhD, RD, Halic University
- Director de estudio: Salim YILMAZ, PhD, Acıbadem Mehmet Ali Aydınlar University
Publicaciones y enlaces útiles
La persona responsable de ingresar información sobre el estudio proporciona voluntariamente estas publicaciones. Estos pueden ser sobre cualquier cosa relacionada con el estudio.
Publicaciones Generales
- Jakubowicz D, Froy O, Ahren B, Boaz M, Landau Z, Bar-Dayan Y, Ganz T, Barnea M, Wainstein J. Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial. Diabetologia. 2014 Sep;57(9):1807-11. doi: 10.1007/s00125-014-3305-x. Epub 2014 Jul 10.
- Kataoka Y, Kamijo YI, Ogawa Y, Sumiyoshi E, Nakae M, Ikegawa S, Manabe K, Morikawa M, Nagata M, Takasugi S, Masuki S, Nose H. Effects of hypervolemia by protein and glucose supplementation during aerobic training on thermal and arterial pressure regulations in hypertensive older men. J Appl Physiol (1985). 2016 Oct 1;121(4):1021-1031. doi: 10.1152/japplphysiol.00033.2016. Epub 2016 May 19.
- Vogtschmidt YD, Raben A, Faber I, de Wilde C, Lovegrove JA, Givens DI, Pfeiffer AFH, Soedamah-Muthu SS. Is protein the forgotten ingredient: Effects of higher compared to lower protein diets on cardiometabolic risk factors. A systematic review and meta-analysis of randomised controlled trials. Atherosclerosis. 2021 Jul;328:124-135. doi: 10.1016/j.atherosclerosis.2021.05.011. Epub 2021 May 26.
- Zhang M, Dong X, Huang Z, Li X, Zhao Y, Wang Y, Zhu H, Fang A, Giovannucci EL. Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies. Adv Nutr. 2023 Sep;14(5):1170-1186. doi: 10.1016/j.advnut.2023.06.007. Epub 2023 Jun 15.
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio (Actual)
12 de diciembre de 2025
Finalización primaria (Actual)
22 de mayo de 2026
Finalización del estudio (Actual)
16 de junio de 2026
Fechas de registro del estudio
Enviado por primera vez
16 de junio de 2026
Primero enviado que cumplió con los criterios de control de calidad
27 de junio de 2026
Publicado por primera vez (Actual)
30 de junio de 2026
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
30 de junio de 2026
Última actualización enviada que cumplió con los criterios de control de calidad
27 de junio de 2026
Última verificación
1 de junio de 2026
Más información
Términos relacionados con este estudio
Palabras clave
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- OkanU-KO-3
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
NO
Descripción del plan IPD
Individual participant data (IPD) will not be shared outside the research team to ensure participant privacy and confidentiality.
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
No
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
No
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .