A review of nutritional factors in hypertension management

Ha Nguyen, Olaide A Odelola, Janani Rangaswami, Aman Amanullah, Ha Nguyen, Olaide A Odelola, Janani Rangaswami, Aman Amanullah

Abstract

Hypertension is a major health problem worldwide. Its attendant morbidity and mortality complications have a great impact on patient's quality of life and survival. Optimizing blood pressure control has been shown to improve overall health outcomes. In addition to pharmacological therapies, nonpharmacological approach such as dietary modification plays an important role in controlling blood pressure. Many dietary components such as sodium, potassium, calcium, and magnesium have been studied substantially in the past decades. While some of these nutrients have clear evidence for their recommendation, some remain controversial and are still of ongoing study. Dietary modification is often discussed with patients and can provide a great benefit in blood pressure regulation. As such, reviewing the current evidence will be very useful in guiding patients and their physician and/or dietician in decision making. In this review article of nutritional factors in hypertension management, we aim to examine the role of nutritional factors individually and as components of whole dietary patterns.

References

    1. Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension. 2003;42(6):1206–1252.
    1. World Health Statistics. 2012, .
    1. Adrogue HJ, Madias NE. Sodium and potassium in the pathogenesis of hypertension. The New England Journal of Medicine. 2007;356(19):1966–1978.
    1. Rose G, Stamler J, Stamler R, et al. Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. British Medical Journal. 1988;297(6644):319–328.
    1. Kawasaki T, Delea CS, Bartter FC, Smith H. The effect of high-sodium and low-sodium intakes on blood pressure and other related variables in human subjects with idiopathic hypertension. American Journal of Medicine. 1978;64(2):193–198.
    1. Koolen MI, Bussemaker-Verduyn Den Boer E, Van Brummelen P. Clinical biochemical and haemodynamic correlates of sodium sensitivity in essential hypertension. Journal of Hypertension. 1983;1(2):21–23.
    1. Luft FC, Grim CE, Willis LR, Higgins JT, Jr., Weinberger MH. Natriuretic response to saline infusion in normotensive and hypertensive man. The role of renin suppression in exaggerated natriuresis. Circulation. 1977;55(5):779–784.
    1. Sullivan JM, Ratts TE. Sodium sensitivity in human subjects. Hemodynamic and hormonal correlates. Hypertension. 1988;11(6):717–723.
    1. Weinberger MH. Salt sensitivity of blood pressure in humans. Hypertension. 1996;27(3):481–490.
    1. Lindheimer MD, Lalone RC, Levinsky NG. Evidence that an acute increase in glomerular filtration has little effect on sodium excretion in the dog unless extracellular volume is expanded. Journal of Clinical Investigation. 1967;46(2):256–265.
    1. Luft FC, Miller JZ, Grim CE, et al. Salt sensitivity and resistance of blood pressure. Age and race as factors in physiological responses. Hypertension. 1991;17(1, supplement):I102–I108.
    1. Rodriguez BL, Labarthe DR, Huang B, Lopez-Gomez J. Rise of blood pressure with age: new evidence of population differences. Hypertension. 1994;24(6):779–785.
    1. Sechi LA. Mechanisms of insulin resistance in rat models of hypertension and their relationships with salt sensitivity. Journal of Hypertension. 1999;17(9):1229–1237.
    1. Ferri C, Bellini C, Desideri G, et al. Clustering of endothelial markers of vascular damage in human salt- sensitive hypertension: influence of dietary sodium load and depletion. Hypertension. 1998;32(5):862–868.
    1. Bigazzi R, Bianchi S, Baldari D, Sgherri G, Baldari G, Campese VM. Microalbuminuria in salt-sensitive patients: a marker for renal and cardiovascular risk factors. Hypertension. 1994;23(2):195–199.
    1. Campese VM, Parise M, Karubian F, Bigazzi R. Abnormal renal hemodynamics in black salt-sensitive patients with hypertension. Hypertension. 1991;18(6):805–812.
    1. Laragh JH, Resnick LM. Recognizing and treating two types of long-term vasoconstriction in hypertension. Kidney International. 1988;34(25):S162–S174.
    1. Ishibashi K, Oshima T, Matsuura H, et al. Effects of age and sex on sodium chloride sensitivity: association with plasma renin activity. Clinical Nephrology. 1994;42(6):376–380.
    1. Torielli L, Tivodar S, Montella RC, et al. α-Adducin mutations increase Na/K pump activity in renal cells by affecting constitutive endocytosis: implications for tubular Na reabsorption. American Journal of Physiology. 2008;295(2):F478–F487.
    1. Stenström K, Takemori H, Bianchi G, Katz AI, Bertorello AM. Blocking the salt-inducible kinase 1 network prevents the increases in cell sodium transport caused by a hypertension-linked mutation in human α-adducin Calmodulin Cytoskeleton Na+K+-AtPase Sodium reabsorption. Journal of Hypertension. 2009;27(12):2452–2457.
    1. Sanada H, Yatabe J, Midorikawa S, et al. Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clinical Chemistry. 2006;52(3):352–360.
    1. Gariepy CE, Ohuchi T, Williams SC, Richardson JA, Yanagisawa M. Salt-sensitive hypertension in endothelin-B receptor-deficient rats. Journal of Clinical Investigation. 2000;105(7):925–933.
    1. De La Sierra A, Lluch MM, Pare JC, et al. Increased left ventricular mass in salt-sensitive hypertensive patients. Journal of Human Hypertension. 1996;10(12):795–799.
    1. Morimoto A, Uzu T, Fujii T, et al. Sodium sensitivity and cardiovascular events in patients with essential hypertension. The Lancet. 1997;350(9093):1734–1737.
    1. Weinberger MH, Fineberg NS, Fineberg SE, Weinberger M. Salt sensitivity, pulse pressure, and death in normal and hypertensive humans. Hypertension. 2001;37(2):429–432.
    1. WHO. Diet, Nutrition and the Prevention of Chronic Diseases. Technical Report Series 916. 2003, .
    1. Khan NA, Hemmelgarn B, Herman RJ, Bell CM, Mahon JL, Leiter LA, et al. The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2—therapy. Canadian Journal of Cardiology. 2009;25(5):287–298.
    1. Appel LJ, Brands MW, Daniels SR, Karanja N, Elmer PJ, Sacks FM. Dietary approaches to prevent and treat hypertension: a scientific statement from the American Heart Association. Hypertension. 2006;47(2):296–308.
    1. Alderman MH. Reducing dietary sodium: the case for caution. Journal of the American Medical Association. 2010;303(5):448–449.
    1. McCarron DA. The dietary guideline for sodium: should we shake it up? Yes! American Journal of Clinical Nutrition. 2000;71(5):1013–1019.
    1. Cutler JA. Effects of weight loss and sodium reduction intervention on blood pressure and hypertension incidence in overweight people with high-normal blood pressure: the trials of hypertension prevention, phase II. Archives of Internal Medicine. 1997;157(6):657–667.
    1. Langford HG, Blaufox MD, Oberman A. Dietary therapy slows the return of hypertension after stopping prolonged medication. Journal of the American Medical Association. 1985;253(5):657–664.
    1. Whelton PK, Appel LJ, Espeland MA, et al. Sodium reduction and weight loss in the treatment of hypertension in older persons: a randomized controlled trial of nonpharmacologic interventions in the elderly (TONE) Journal of the American Medical Association. 1998;279(11):839–846.
    1. He FJ, MacGregor GA. Effect of modest salt reduction on blood pressure: a meta-analysis of randomized trials. Implications for public health. Journal of Human Hypertension. 2002;16(11):761–770.
    1. Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension (dash) diet. The New England Journal of Medicine. 2001;344(1):3–10.
    1. Bray GA, Vollmer WM, Sacks FM, Obarzanek E, Svetkey LP, Appel LJ. A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: results of the DASH-sodium trial. American Journal of Cardiology. 2004;94(2):222–227.
    1. Cook NR, Cutler JA, Obarzanek E, et al. Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP) British Medical Journal. 2007;334(7599):885–888.
    1. Tuomilehto J, Jousilahti P, Rastenyte D, et al. Urinary sodium excretion and cardiovascular mortality in Finland: a prospective study. The Lancet. 2001;357(9259):848–851.
    1. Strazzullo P, D’Elia L, Kandala NB, Cappuccio FP. Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies. British Medical Journal. 2009;339b4567
    1. Alderman MH, Madhavan S, Cohen H, et al. Low urinary sodium is associated with greater risk of myocardial infarction among treated hypertensive men. Hypertension. 1995;25(6):1144–1152.
    1. Alderman MH, Cohen H, Madhavan S. Dietary sodium intake and mortality: the National Health and Nutrition Examination Survey (NHANES I) The Lancet. 1998;351(9105):781–785.
    1. Stolarz-Skrzypek K, Kuznetsova T, Thijs L, et al. Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion. Journal of the American Medical Association. 2011;305(17):1777–1785.
    1. Jürgens G, Graudal NA. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride. Cochrane Database of Systematic Reviews. 2003;(1)CD004022
    1. Weder AB, Egan BM. Potential deleterious impact of dietary salt restriction on cardiovascular risk factors. Klinische Wochenschrift. 1991;69(supplement 25):45–50.
    1. Iwaoka T, Umeda T, Ohno M, et al. The effect of low and high NaCl diets on oral glucose tolerance. Klinische Wochenschrift. 1988;66(16):724–728.
    1. Masugi F, Ogihara T, Hashizume K, Hasegawa T, Sakaguchi K, Kumahara Y. Changes in plasma lipids and uric acid with sodium loading and sodium depletion in patients with essential hypertension. Journal of Human Hypertension. 1988;1(4):293–298.
    1. Paterna S, Gaspare P, Fasullo S, Sarullo FM, Di Pasquale P. Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend? Clinical Science. 2008;114(3-4):221–230.
    1. Paterna S, Parrinello G, Cannizzaro S, et al. Medium term effects of different dosage of diuretic, sodium, and fluid administration on neurohormonal and clinical outcome in patients with recently compensated heart failure. American Journal of Cardiology. 2009;103(1):93–102.
    1. Thomas MC, Moran J, Forsblom C, et al. The association between dietary sodium intake, ESRD, and all-cause mortality in patients with type 1 diabetes. Diabetes Care. 2011;34(4):861–866.
    1. Ekinci EI, Clarke S, Thomas MC, et al. Dietary salt intake and mortality in patients with type 2 diabetes. Diabetes Care. 2011;34(3):703–709.
    1. De La Sierra A, Del Mar Lluch M, Coca A, et al. Assessment of salt sensitivity in essential hypertension by 24-h ambulatory blood pressure monitoring. American Journal of Hypertension. 1995;8(10):970–977.
    1. Galletti F, Ferrara I, Stinga F, Iacone R, Noviello F, Strazzullo P. Evaluation of a rapid protocol for the assessment of salt sensitivity against the blood pressure response to dietary sodium chloride restriction. American Journal of Hypertension. 1997;10(4):462–466.
    1. Laffer CL, Elijovich F. Essential hypertension of Caribbean hispanics: sodium, renin, and response to therapy. Journal of Clinical Hypertension. 2002;4(4):266–273.
    1. Fludrocortisone's Test in Salt Sensitivity. 2012, .
    1. WHO. Guideline: sodium intake for adults and children. World Health Organization (WHO), 2012, .
    1. Khaw KT, Barrett-Connor E. Dietary potassium and blood pressure in a population. American Journal of Clinical Nutrition. 1984;39(6):963–968.
    1. Geleijnse JM, Witteman JCM, Den Breeijen JH, et al. Dietary electrolyte intake and blood pressure in older subjects: the Rotterdam Study. Journal of Hypertension. 1996;14(6):737–741.
    1. Krishna GG, Kapoor SC. Potassium depletion exacerbates essential hypertension. Annals of Internal Medicine. 1991;115(2):77–83.
    1. Cappuccio FP, MacGregor GA. Does potassium supplementation lower blood pressure? A meta-analysis of published trials. Journal of Hypertension. 1991;9(5):465–473.
    1. Geleijnse JM, Kok FJ, Grobbee DE. Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials. Journal of Human Hypertension. 2003;17(7):471–480.
    1. Dickinson HO, Nicolson DJ, Campbell F, Beyer FR, Mason J. Potassium supplementation for the management of primary hypertension in adults. Cochrane Database of Systematic Reviews. 2006;3CD004641
    1. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure: meta-analysis of randomized controlled clinical trials. Journal of the American Medical Association. 1997;277(20):1624–1632.
    1. Van Den Hoogen PCW, Feskens EJM, Nagelkerke NJD, Menotti A, Nissinen A, Kromhout D. The relation between blood pressure and mortality due to coronary heart disease among men in different parts of the world. The New England Journal of Medicine. 2000;342(1):1–8.
    1. Rodgers A, MacMahon S, Gamble G, Slattery J, Sandercock P, Warlow C. Blood pressure and risk of stroke in patients with cerebrovascular disease. British Medical Journal. 1996;313(7050, article 147)
    1. Rashid P, Leonardi-Bee J, Bath P. Blood pressure reduction and secondary prevention of stroke and other vascular events: a systematic review. Stroke. 2003;34(11):2741–2748.
    1. Yang Q, Liu T, Kuklina EV, et al. Sodium and potassium intake and mortality among US adults: prospective data from the third national health and nutrition examination survey. Archives of Internal Medicine. 2011;171(13):1183–1191.
    1. Khaw KT, Barrett-Connor E. Dietary of potassium and stroke-associated mortality. A 12-year prospective population study. The New England Journal of Medicine. 1987;316(5):235–240.
    1. Brandis M, Keyes J, Windhager EE. Potassium-induced inhibition of proximal tubular fluid reabsorption in rats. The American Journal of Physiology. 1972;222(2):421–427.
    1. Vander AJ. Direct effects of potassium on renin secretion and renal function. The American Journal of Physiology. 1970;219(2):455–459.
    1. Pamnani MB, Chen X, Haddy FJ, Schooley JF, Mo Z. Mechanism of antihypertensive effect of dietary potassium in experimental volume expanded hypertension in rats. Clinical and Experimental Hypertension. 2000;22(6):555–569.
    1. Edwards G, Dora KA, Gardener MJ, Garland CJ, Weston AH. K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature. 1998;396(6708):269–272.
    1. Kuschinsky W, Wahl M, Bosse O, Thurau K. Perivascular potassium and pH as determinants of local pial arterial diameter in cats. A microapplication study. Circulation Research. 1972;31(2):240–247.
    1. Zhou MS, Nishida Y, Yoneyama H, Chen QH, Kosaka H. Potassium supplementation increases sodium excretion and nitric oxide production in hypertensive Dahl rats. Clinical and Experimental Hypertension. 1999;21(8):1397–1411.
    1. Knot HJ, Zimmermann PA, Nelson MT. Extracellular K+-induced hyperpolarizations and dilatations of rat coronary and cerebral arteries involve inward rectifier K+ channels. Journal of Physiology. 1996;492(2):419–430.
    1. Kido M, Ando K, Onozato ML, et al. Protective effect of dietary potassium against vascular injury in salt-sensitive hypertension. Hypertension. 2008;51(2):225–231.
    1. Ishimitsu T, Tobian L, Sugimoto K, Everson T. High potassium diets reduce vascular and plasma lipid peroxides in stroke-prone spontaneously hypertensive rats. Clinical and Experimental Hypertension. 1996;18(5):659–673.
    1. National Research Council. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC, USA: The National Academies Press; 2005.
    1. Whitworth JA. 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. Journal of Hypertension. 2003;21(11):1983–1992.
    1. Cogswell ME, Zhang Z, Carriquiry AL, Gunn JP, Kuklina EV, Saydah SH, et al. Sodium and potassium intakes among US adults: NHANES, 2003–2008. American Journal of Clinical Nutrition. 2012;96(3):647–657.
    1. Männistö S, Ovaskainen ML, Valsta L. The National Findiet 2002 Study. Publications of the National Public Health Institute; 2003.
    1. Henderson LIK, Gregory J, Bates CJ, et al. The National Diet & Nutrition Survey: Adults Aged 19 to 64 Years. Vol. 3. London, UK: Food Standards Agency and the Departments of Health by the Social Survey Division of the Office for National Statistics and Medical Research Council Human Nutrition Research; 2003. (Vitamin and Mineral intake and Urinary Analytes).
    1. Tian HG, Hu G, Dong QN, et al. Dietary sodium and potassium, socioeconomic status and blood pressure in a Chinese population. Appetite. 1996;26(3):235–246.
    1. Reed D, McGee D, Yano K, Hankin J. Diet, blood pressure, and multicollinearity. Hypertension. 1985;7(3):405–410.
    1. Dwyer JH, Li L, Dwyer KM, Curtin LR, Feinleib M. Dietary calcium, alcohol, and incidence of treated hypertension in the NHANES I epidemiologic follow-up study. American Journal of Epidemiology. 1996;144(9):828–838.
    1. Witteman JCM, Willett WC, Stampfer MJ, et al. A prospective study of nutritional factors and hypertension among US women. Circulation. 1989;80(5):1320–1327.
    1. Wang L, Manson JE, Buring JE, Lee IM, Sesso HD. Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older women. Hypertension. 2008;51(4):1073–1079.
    1. Cutler JA, Brittain E. Calcium and blood pressure. An epidemiologic perspective. American Journal of Hypertension. 1990;3(8):137S–146S.
    1. Ascherio A, Rimm EB, Giovannucci EL, et al. A prospective study of nutritional factors and hypertension among US men. Circulation. 1992;86(5):1475–1484.
    1. McCarron DA, Morris CD, Henry HJ, Stanton JL. Blood pressure and nutrient intake in the United States. Science. 1984;224(4656):1392–1398.
    1. Belizan JM, Villar J, Pineda O. Reduction of blood pressure with calcium supplementation in young adults. Journal of the American Medical Association. 1983;249(9):1161–1165.
    1. McCarron DA, Morris CD. Blood pressure response to oral calcium in persons with mild to moderate hypertension: a randomized, double-blind, placebo-controlled, crossover trial. Annals of Internal Medicine. 1985;103(6):825–831.
    1. Grobbee DE, Hofman A. Effect of calcium supplementation on diastolic blood pressure in young people with mild hypertension. The Lancet. 1986;2(8509):703–706.
    1. Strazzullo P, Siani A, Guglielmi S. Controlled trial of long-term oral calcium supplementation in essential hypertension. Hypertension. 1986;8(11):1084–1088.
    1. Ascherio A, Hennekens C, Willett WC, et al. Prospective study of nutritional factors, blood pressure, and hypertension among US women. Hypertension. 1996;27(5):1065–1072.
    1. Davis IJ, Grim C, Dwyer K, Nicholson L, Dwyer J. The effects of calcium supplementation on ambulatory blood pressure in african-american adolescents. Journal of the National Medical Association. 1996;88(12):774–778.
    1. Cappuccio FP, Markandu ND, Singer DRJ. Does oral calcium supplementation lower high blood pressure? A double blind study. Journal of Hypertension. 1987;5(1):67–71.
    1. Cappuccio FP, Siani A, Strazzullo P. Oral calcium supplementation and blood pressure: an overview of randomized controlled trials. Journal of Hypertension. 1989;7(12):941–946.
    1. Griffith LE, Guyatt GH, Cook RJ, Bucher HC, Cook DJ. The influence of dietary and nondietary calcium supplementation on blood pressure: an updated metaanalysis of randomized controlled trials. American Journal of Hypertension. 1999;12(1):84–92.
    1. The effects of nonpharmacologic interventions on blood pressure of persons with high normal levels. Results of the trials of hypertension prevention, phase I. Journal of the American Medical Association. 1992;267(9):1213–1220.
    1. Gruchow HW, Sobocinski KA, Barboriak JJ. Alcohol, nutrient intake, and hypertension in US adults. Journal of the American Medical Association. 1985;253(11):1567–1570.
    1. Feinleib M, Lenfant C, Miller SA. Hypertension and calcium. Science. 1984;226(4673):386–393.
    1. Sempos C, Cooper R, Kovar MG. Dietary calcium and blood pressure in National Health and Nutrition Examination Surveys I and II. Hypertension. 1986;8(11):1067–1074.
    1. Harlan WR, Hull AL, Schmouder RL, Landis JR, Thompson FE, Larkin FA. Blood pressure and nutrition in adults. The National Health and Nutrition Examination Survey. American Journal of Epidemiology. 1984;120(1):17–28.
    1. Allender PS, Cutler JA, Follmann D, Cappuccio FP, Pryer J, Elliott P. Dietary calcium and blood pressure: a meta-analysis of randomized clinical trials. Annals of Internal Medicine. 1996;124(9):825–831.
    1. Bucher HC, Cook RJ, Guyatt GH, et al. Effects of dietary calcium supplementation on blood pressure: a meta-analysis of randomized controlled trials. Journal of the American Medical Association. 1996;275(13):1016–1022.
    1. van Mierlo LAJ, Arends LR, Streppel MT, et al. Blood pressure response to calcium supplementation: a meta-analysis of randomized controlled trials. Journal of Human Hypertension. 2006;20(8):571–580.
    1. Dickinson HO, Nicolson DJ, Cook JV, et al. Calcium supplementation for the management of primary hypertension in adults. Cochrane Database of Systematic Reviews. 2006;(2)CD004639
    1. Houston MC, Harper KJ. Potassium, magnesium, and calcium: their role in both the cause and treatment of hypertension. Journal of Clinical Hypertension. 2008;10(7):3–11.
    1. McCarron DA. Role of adequate dietary calcium intake in the prevention and management of salt-sensitive hypertension. American Journal of Clinical Nutrition. 1997;65(2):712S–716S.
    1. Yamakawa H, Suzuki H, Nakamura M, Ohno Y, Saruta T. Disturbed calcium metabolism in offspring of hypertensive parents. Hypertension. 1992;19(6):528–534.
    1. Lijnen P, Petrov V. Dietary calcium, blood pressure and cell membrane cation transport systems in males. Journal of Hypertension. 1995;13(8):875–882.
    1. Saito K, Sano H, Furuta Y, Fukuzaki H. Effect of oral calcium on blood pressure response in salt-loaded borderline hypertensive patients. Hypertension. 1989;13(3):219–226.
    1. Hatton DC, McCarron DA. Dietary calcium and blood pressure in experimental models of hypertension: a review. Hypertension. 1994;23(4):513–530.
    1. Sowers JR, Zemel MB, Zemel PC, Standley PR. Calcium metabolism and dietary calcium in salt sensitive hypertension. American Journal of Hypertension. 1991;4(6):557–563.
    1. Hamet P, Mongeau E, Lambert J, et al. Interactions among calcium, sodium, and alcohol intake as determinants of blood pressure. Hypertension. 1991;17(1, supplement):I150–I154.
    1. Hamet P, Daignault-Gelinas M, Lambert J, et al. Epidemiological evidence of an interaction between calcium and sodium intake impacting on blood pressure. A Montreal Study. American Journal of Hypertension. 1992;5(6):378–385.
    1. Gruchow HW, Sobocinski KA, Barboriak JJ. Calcium intake and the relationship of dietary sodium and potassium to blood pressure. American Journal of Clinical Nutrition. 1988;48(6):1463–1470.
    1. Kotchen TA, McCarron DA. Dietary electrolytes and blood pressure: a statement for healthcare professionals from the American Heart Association Nutrition Committee. Circulation. 1998;98(6):613–617.
    1. Weinberger MH, Wagner UL, Fineberg NS. The blood pressure effects of calcium supplementation in humans of known sodium responsiveness. American Journal of Hypertension. 1993;6(9):799–805.
    1. Resnick LM, Muller FB, Laragh JH. Calcium-regulating hormones in essential hypertension: relation to plasma renin activity and sodium metabolism. Annals of Internal Medicine. 1986;105(5):649–654.
    1. Resnick LM, Nicholson JP, Laragh JH. Calcium metabolism in essential hypertension: relationship to altered renin system activity. Federation Proceedings. 1986;45(12):2739–2745.
    1. Resnick LM, Laragh JH. Renin, calcium metabolism and the pathophysiologic basis of antihypertensive therapy. American Journal of Cardiology. 1985;56(16):H68–H74.
    1. Resnick LM, Nicholson JP, Laragh JH. Alterations in calcium metabolism mediate dietary salt sensitivity in essential hypertension. Transactions of the Association of American Physicians. 1985;98:313–321.
    1. Resnick LM, Laragh JH, Sealey JE, Alderman MH. Divalent cations in essential hypertension. Relations between serum ionized calcium, magnesium, and plasma renin activity. The New England Journal of Medicine. 1983;309(15):888–891.
    1. Resnick LM, Laragh JH. The significance of calcium and calcium channel blockade in essential hypertension. Journal of Hypertension. 1985;3(3):S541–S544.
    1. Resnick L. Calcium metabolism, renin activity, and the antihypertensive effects of calcium channel blockade. The American Journal of Medicine. 1986;81(6):6–14.
    1. Resnick LM. The effects of sodium and calcium in clinical hypertension: mediating role of vitamin D metabolism. Advances in Second Messenger and Phosphoprotein Research. 1990;24:535–541.
    1. Resnick LM. Alterations of dietary calcium intake as a therapeutic modality in essential hypertension. Canadian Journal of Physiology and Pharmacology. 1986;64(6):803–807.
    1. Altura BM, Altura BT, Gebrewold A. Magnesium deficiency and hypertension: correlation between magnesium-deficient diets and microcirculatory changes in situ. Science. 1984;223(4642):1315–1317.
    1. Ma J, Folsom AR, Melnick SL, et al. Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness: the aric study. Journal of Clinical Epidemiology. 1995;48(7):927–940.
    1. Mizushima S, Cappuccio FP, Nichols R, Elliott P. Dietary magnesium intake and blood pressure: a qualitative overview of the observational studies. Journal of Human Hypertension. 1998;12(7):447–453.
    1. Dickinson HO, Nicolson DJ, Campbell F, et al. Magnesium supplementation for the management of essential hypertension in adults. Cochrane Database of Systematic Reviews. 2006;3CD004640
    1. Jee SHA, Miller ER, Guallar E, Singh VK, Appel LJ, Klag MJ. The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials. American Journal of Hypertension. 2002;15(8):691–696.
    1. Centers for Disease Control and Prevention. 2012, .
    1. Australian Government Department of Health and Aging. 2012, .
    1. Beulens JWJ, Rimm EB, Ascherio A, Spiegelman D, Hendriks HFJ, Mukamal KJ. Alcohol consumption and risk for coronary heart disease among men with hypertension. Annals of Internal Medicine. 2007;146(1):10–19.
    1. Nakanishi N, Yoshida H, Nakamura K, Suzuki K, Tatara K. Alcohol consumption and risk for hypertension in middle-aged Japanese men. Journal of Hypertension. 2001;19(5):851–855.
    1. Thadhani R, Camargo CA, Stampfer MJ, Curhan GC, Willett WC, Rimm EB. Prospective study of moderate alcohol consumption and risk of hypertension in young women. Archives of Internal Medicine. 2002;162(5):569–574.
    1. Fuchs FD, Chambless LE, Whelton PK, Nieto FJ, Heiss G. Alcohol consumption and the incidence of hypertension: the Atherosclerosis Risk in Communities Study. Hypertension. 2001;37(5):1242–1250.
    1. Marmot MG, Elliott P, Shipley MJ, et al. Alcohol and blood pressure: the INTERSALT Study. British Medical Journal. 1994;308(6939):1263–1267.
    1. Xin X, He J, Frontini MG, Ogden LG, Motsamai OI, Whelton PK. Effects of alcohol reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension. 2001;38(5):1112–1117.
    1. Streppel MT, Arends LR, Van’t Veer P, Grobbee DE, Geleijnse JM. Dietary fiber and blood pressure: a meta-analysis of randomized placebo-controlled trials. Archives of Internal Medicine. 2005;165(2):150–156.
    1. He J, Streiffer RH, Muntner P, Krousel-Wood MA, Whelton PK. Effect of dietary fiber intake on blood pressure: a randomized, double-blind, placebo-controlled trial. Journal of Hypertension. 2004;22(1):73–80.
    1. Mori TA, Burke V, Puddey IB, Shaw JE, Beilin LJ. Effect of fish diets and weight loss on serum leptin concentration in overweight, treated-hypertensive subjects. Journal of Hypertension. 2004;22(10):1983–1990.
    1. Bonaa KH, Bjerve KS, Straume B, Gram IT, Thelle D. Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study. The New England Journal of Medicine. 1990;322(12):795–801.
    1. Knapp HR, Fitzgerald GA. The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension. The New England Journal of Medicine. 1989;320(16):1037–1043.
    1. Mozaffarian D, Shi P, Morris JS, Grandjean P, Siscovick DS, Spiegelman D, et al. Mercury exposure and risk of hypertension in US men and women in 2 prospective cohorts. Hypertension. 2012;60(3):645–652.
    1. Reinhart KM, Coleman CI, Teevan C, Vachhani P, White CM. Effects of garlic on blood pressure in patients with and without systolic hypertension: a meta-analysis. Annals of Pharmacotherapy. 2008;42(12):1766–1771.
    1. Ried K, Frank OR, Stocks NP, Fakler P, Sullivan T. Effect of garlic on blood pressure: a systematic review and meta-analysis. BMC Cardiovascular Disorders. 2008;8, article 13
    1. Sharp DS, Benowitz NL. Pharmacoepidemiology of the effect of caffeine on blood pressure. Clinical Pharmacology and Therapeutics. 1990;47(1):57–60.
    1. Winkelmayer WC, Stampfer MJ, Willett WC, Curhan GC. Habitual caffeine intake and the risk of hypertension in women. Journal of the American Medical Association. 2005;294(18):2330–2335.
    1. Sudano I, Spieker L, Binggeli C, et al. Coffee blunts mental stress-induced blood pressure increase in habitual but not in nonhabitual coffee drinkers. Hypertension. 2005;46(3):521–526.
    1. Corti R, Binggeli C, Sudano I, et al. Coffee acutely increases sympathetic nerve activity and blood pressure independently of caffeine content role of habitual versus nonhabitual drinking. Circulation. 2002;106(23):2935–2940.
    1. Morris DJ, Davis E, Latif SA. Licorice, tobacco chewing, and hypertension. The New England Journal of Medicine. 1990;322(12):849–850.
    1. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. The New England Journal of Medicine. 1997;336(16):1117–1124.
    1. Svetkey LP, Simons-Morton D, Vollmer WM, et al. Effects of dietary patterns on blood pressure: subgroup analysis of the Dietary Approaches to Stop Hypertension (DASH) randomized clinical trial. Archives of Internal Medicine. 1999;159(3):285–293.
    1. Epstein DE, Sherwood A, Smith PJ, Craighead L, Caccia C, Lin PH, et al. Determinants and consequences of adherence to the dietary approaches to stop hypertension diet in African-American and white adults with high blood pressure: results from the ENCORE trial. Journal of the Academy of Nutrition and Dietetics. 2012;112(11):1763–1773.
    1. Mitka M. DASH dietary plan could benefit many, but few hypertensive patients follow it. Journal of the American Medical Association. 2007;298(2):164–165.
    1. Vollmer WM, Sacks FM, Ard J, et al. Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial. Annals of Internal Medicine. 2001;135(12):1019–1028.
    1. Blumenthal JA, Babyak MA, Hinderliter A, et al. Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study. Archives of Internal Medicine. 2010;170(2):126–135.
    1. Fung TT, Chiuve SE, McCullough ML, Rexrode KM, Logroscino G, Hu FB. Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women. Archives of Internal Medicine. 2008;168(7):713–720.
    1. Parikh A, Lipsitz SR, Natarajan S. Association between a DASH-like diet and mortality in adults with hypertension: findings from a population-based follow-up study. American Journal of Hypertension. 2009;22(4):409–416.
    1. Levitan EB, Wolk A, Mittleman MA. Relation of consistency with the dietary approaches to stop hypertension diet and incidence of heart failure in men aged 45 to 79 years. American Journal of Cardiology. 2009;104(10):1416–1420.
    1. Levitan EB, Wolk A, Mittleman MA. Consistency with the DASH diet and incidence of heart failure. Archives of Internal Medicine. 2009;169(9):851–857.
    1. Obarzanek E, Sacks FM, Vollmer WM, et al. Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial. American Journal of Clinical Nutrition. 2001;74(1):80–89.
    1. Chen ST, Maruthur NM, Appel LJ. The effect of dietary patterns on estimated coronary heart disease risk results from the Dietary Approaches to Stop Hypertension (DASH) trial. Circulation. 2010;3(5):484–489.
    1. Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi T, Azizi F. Beneficial effects of a dietary approaches to stop hypertension eating plan on features of the metabolic syndrome. Diabetes Care. 2005;28(12):2823–2831.
    1. De Koning L, Chiuve SE, Fung TT, Willett WC, Rimm EB, Hu FB. Diet-quality scores and the risk of type 2 diabetes in men. Diabetes Care. 2011;34(5):1150–1156.
    1. Lichtenstein AH, Appel LJ, Brands M, et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the American heart association nutrition committee. Circulation. 2006;114(1):82–96.
    1. Handelsman Y, Mechanick JI, Blonde L, Grunberger G, Bloomgarden ZT, Bray GA, et al. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care plan. Endocrine Practice. 2011;17(supplement 2):1–53.
    1. US Department of Health and Human Services. Your Guide To Lowering Your Blood Pressure With DASH. 2006, .
    1. Appel LJ. Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. Journal of the American Medical Association. 2003;289(16):2083–2093.
    1. Armstrong B, Van Merwyk AJ, Coates H. Blood pressure in Seventh Day Adventist vegetarians. American Journal of Epidemiology. 1977;105(5):444–449.
    1. Armstrong B, Clarke H, Martin C. Urinary sodium and blood pressure in vegetarians. American Journal of Clinical Nutrition. 1979;32(12):2472–2476.
    1. Pettersen BJ, Anousheh R, Fan J, Jaceldo-Siegl K, Fraser GE. Vegetarian diets and blood pressure among white subjects: results from the Adventist Health Study-2 (AHS-2) Public Health Nutrition. 2012;15(10):1909–1916.
    1. Margetts BM, Beilin LJ, Vandongen R, Armstrong BK. Vegetarian diet in mild hypertension: a randomised controlled trial. British Medical Journal. 1986;293(6560):1468–1471.
    1. Rouse IL, Armstrong BK, Beilin LJ, Vandongen R. Blood-pressure-lowering effect of a vegetarian diet: controlled trial in normotensive subjects. The Lancet. 1983;1(8314):5–10.

Source: PubMed

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