Update from PSMA-SRT Trial NCT03582774: A Randomized Phase 3 Imaging Trial of Prostate-specific Membrane Antigen Positron Emission Tomography for Salvage Radiation Therapy for Prostate Cancer Recurrence Powered for Clinical Outcome

Jeremie Calais, Wesley R Armstrong, Amar U Kishan, Kiara M Booker, Thomas A Hope, Wolfgang P Fendler, David Elashoff, Nicholas G Nickols, Johannes Czernin, Jeremie Calais, Wesley R Armstrong, Amar U Kishan, Kiara M Booker, Thomas A Hope, Wolfgang P Fendler, David Elashoff, Nicholas G Nickols, Johannes Czernin

Abstract

The purpose of this randomized trial is to evaluate the success rate of salvage radiation therapy for recurrence of prostate cancer after radical prostatectomy, with and without planning based on prostate-specific membrane antigen positron emission tomography/computed tomography. Enrollment has been completed and patients are being followed for 5yr.

Trial registration: ClinicalTrials.gov NCT03582774.

Copyright © 2020 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Figures

Fig. 1 –
Fig. 1 –
Study flowchart. CT = computed tomography; PET = positron emission tomography; PSA = prostate-specific antigen; PSMA = prostate-specific membrane antigen; SRT = salvage radiotherapy.

Source: PubMed

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