Investigating the Extremes of Antibiotic Use with an Epidemiologic Framework
Marc H Scheetz, Page E Crew, Cristina Miglis, Elise M Gilbert, Sarah H Sutton, J Nick O'Donnell, Michael Postelnick, Teresa Zembower, Nathaniel J Rhodes, Marc H Scheetz, Page E Crew, Cristina Miglis, Elise M Gilbert, Sarah H Sutton, J Nick O'Donnell, Michael Postelnick, Teresa Zembower, Nathaniel J Rhodes
Abstract
Benchmarks for judicious use of antimicrobials are needed. Metrics such as defined daily doses (DDDs) and days of therapy (DOTs) quantify antimicrobial consumption. However, benchmarking with these metrics is complicated by interhospital variability. Thus, it is important for each hospital to monitor its own temporal consumption trends. Time series analyses allow trends to be detected; however, many of these methods are complex. We present simple regressive methods and caveats in using them to define potential antibiotic over- and underutilizations.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.
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Source: PubMed