Rationale for a home dialysis virtual ward: design and implementation

Michael E Schachter, Joanne M Bargman, Michael Copland, Michelle Hladunewich, Karthik K Tennankore, Adeera Levin, Matthew Oliver, Robert P Pauly, Jeffrey Perl, Deborah Zimmerman, Christopher T Chan, Michael E Schachter, Joanne M Bargman, Michael Copland, Michelle Hladunewich, Karthik K Tennankore, Adeera Levin, Matthew Oliver, Robert P Pauly, Jeffrey Perl, Deborah Zimmerman, Christopher T Chan

Abstract

Background: Home-based renal replacement therapy (RRT) [peritoneal dialysis (PD) and home hemodialysis (HHD)] offers independent quality of life and clinical advantages compared to conventional in-center hemodialysis. However, follow-up may be less complete for home dialysis patients following a change in care settings such as post hospitalization. We aim to implement a Home Dialysis Virtual Ward (HDVW) strategy, which is targeted to minimize gaps of care.

Methods/design: The HDVW Pilot Study will enroll consecutive PD and HHD patients who fulfilled any one of our inclusion criteria: 1. following discharge from hospital, 2. after interventional procedure(s), 3. prescription of anti-microbial agents, or 4. following completion of home dialysis training. Clinician-led telephone interviews are performed weekly for 2 weeks until VW discharge. Case-mix (modified Charlson Comorbidity Index), symptoms (the modified Edmonton Symptom Assessment Scale) and patient satisfaction are assessed serially. The number of VW interventions relating to eight pre-specified domains will be measured. Adverse events such as re-hospitalization and health-services utilization will be ascertained through telephone follow-up after discharge from the VW at 2, 4, 12 weeks. The VW re-hospitalization rate will be compared with a contemporary cohort (matched for age, gender, renal replacement therapy and co-morbidities). Our protocol has been approved by research ethics board (UHN: 12-5397-AE). Written informed consent for participation in the study will be obtained from participants.

Discussion: This report serves as a blueprint for the design and implementation of a novel health service delivery model for home dialysis patients. The major goal of the HDVW initiative is to provide appropriate and effective supports to medically complex patients in a targeted window of vulnerability.

Trial registration: (NCT01912001).

Figures

Figure 1
Figure 1
Projected virtual ward study design flow diagram.

References

    1. McFarlane PA, Bayoumi AM, Pierratos A, Redelmeier DA. The quality of life and cost utility of home nocturnal and conventional in-center hemodialysis. Kidney Int. 2003;64(3):1004–1011. doi: 10.1046/j.1523-1755.2003.00157.x.
    1. Lockridge RS Jr, Spencer M, Craft V, Pipkin M, Campbell D, McPhatter L, Albert J, Anderson H, Jennings F, Barger T. Nightly home hemodialysis: five and one-half years of experience in Lynchburg, Virginia. Hemodial Int. 2004;8(1):61–69. doi: 10.1111/j.1492-7535.2004.00076.x.
    1. Rubin HR, Fink NE, Plantinga LC, Sadler JH, Kliger AS, Powe NR. Patient ratings of dialysis care with peritoneal dialysis vs hemodialysis. JAMA. 2004;291(6):697–703. doi: 10.1001/jama.291.6.697.
    1. Juergensen E, Wuerth D, Finkelstein SH, Juergensen PH, Bekui A, Finkelstein FO. Hemodialysis and peritoneal dialysis: patients’ assessment of their satisfaction with therapy and the impact of the therapy on their lives. Clin J Am Soc Nephrol. 2006;1(6):1191–1196. doi: 10.2215/CJN.01220406.
    1. Johansen KL, Zhang R, Huang Y, Chen SC, Blagg CR, Goldfarb-Rumyantzev AS, Hoy CD, Lockridge RS Jr, Miller BW, Eggers PW. et al.Survival and hospitalization among patients using nocturnal and short daily compared to conventional hemodialysis: a USRDS study. Kidney Int. 2009;76(9):984–990. doi: 10.1038/ki.2009.291.
    1. Kjellstrand CM, Buoncristiani U, Ting G, Traeger J, Piccoli GB, Sibai-Galland R, Young BA, Blagg CR. Short daily haemodialysis: survival in 415 patients treated for 1006 patient-years. Nephrol Dial Transplant. 2008;23(10):3283–3289. doi: 10.1093/ndt/gfn210.
    1. Pauly RP, Gill JS, Rose CL, Asad RA, Chery A, Pierratos A, Chan CT. Survival among nocturnal home haemodialysis patients compared to kidney transplant recipients. Nephrol Dial Transplant. 2009;24(9):2915–2919. doi: 10.1093/ndt/gfp295.
    1. Weinhandl ED, Foley RN, Gilbertson DT, Arneson TJ, Snyder JJ, Collins AJ. Propensity-matched mortality comparison of incident hemodialysis and peritoneal dialysis patients. Clin J Am Soc Nephrol. 2010;21(3):499–506. doi: 10.1681/ASN.2009060635.
    1. Weinhandl ED, Liu J, Gilbertson DT, Arneson TJ, Collins AJ. Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients. J Am Soc Nephrol. 2012;23(5):895–904. doi: 10.1681/ASN.2011080761.
    1. Lacson E Jr, Xu J, Suri RS, Nesrallah G, Lindsay R, Garg AX, Lester K, Ofsthun N, Lazarus M, Hakim RM. Survival with three-times weekly in-center nocturnal versus conventional hemodialysis. J Am Soc Nephrol. 2012;23(4):687–695. doi: 10.1681/ASN.2011070674.
    1. Komenda P, Gavaghan MB, Garfield SS, Poret AW, Sood MM. An economic assessment model for in-center, conventional home, and more frequent home hemodialysis. Kidney Int. 2012;81(3):307–313. doi: 10.1038/ki.2011.338.
    1. Guo A, Mujais S. Patient and technique survival on peritoneal dialysis in the United States: evaluation in large incident cohorts. Kidney Int Suppl. 2003;88:S3–S12.
    1. Cafazzo JA, Leonard K, Easty AC, Rossos PG, Chan CT. Patient-perceived barriers to the adoption of nocturnal home hemodialysis. Clin J Am Soc Nephrol. 2009;4(4):784–789. doi: 10.2215/CJN.05501008.
    1. Pauly RP, Maximova K, Coppens J, Asad RA, Pierratos A, Komenda P, Copland M, Nesrallah GE, Levin A, Chery A. et al.Patient and technique survival among a Canadian multicenter nocturnal home hemodialysis cohort. Clin J Am Soc Nephrol. 2010;5(10):1815–1820. doi: 10.2215/CJN.00300110.
    1. Piccoli GB FM, Consiglio V, Scognamiglio S, Deagostini MC, Randone O, Vigotti FN, Calderale PM. Why home hemodialysis? A systematic “marketing” analysis. J Nephrol. 2012;25(2):159–169. doi: 10.5301/jn.5000088.
    1. Coleman EA, Parry C, Chalmers S, Min SJ. The care transitions intervention: results of a randomized controlled trial. Arch Intern Med. 2006;166(17):1822–1828. doi: 10.1001/archinte.166.17.1822.
    1. Forster AJ, Murff HJ, Peterson JF, Gandhi TK, Bates DW. The incidence and severity of adverse events affecting patients after discharge from the hospital. Ann Intern Med. 2003;138(3):161–167. doi: 10.7326/0003-4819-138-3-200302040-00007.
    1. Bisognano M, Boutwell A. Improving transitions to reduce readmissions. Front Health Serv Manage. 2009;25(3):3–10.
    1. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009;360(14):1418–1428. doi: 10.1056/NEJMsa0803563.
    1. Lewis GBM, Vaithianathan R, Steventon A, Georghiou T, Billings J, Dixon J. Do ‘virtual wards’ reduce rates of unplanned hospital admissions, and at what cost? A research protocol using propensity matched controls. Int J Integr Care. 2011;11(18):1–8.
    1. Hemmelgarn BR, Manns BJ, Quan H, Ghali WA. Adapting the Charlson Comorbidity Index for use in patients with ESRD. Am J Kidney Dis. 2003;42(1):125–132. doi: 10.1016/S0272-6386(03)00415-3.
    1. Davison SN, Jhangri GS, Johnson JA. Cross-sectional validity of a modified Edmonton symptom assessment system in dialysis patients: a simple assessment of symptom burden. Kidney Int. 2006;69(9):1621–1625. doi: 10.1038/sj.ki.5000184.
    1. Murtagh FE, Addington-Hall JM, Edmonds PM, Donohoe P, Carey I, Jenkins K, Higginson IJ. Symptoms in advanced renal disease: a cross-sectional survey of symptom prevalence in stage 5 chronic kidney disease managed without dialysis. J Palliat Med. 2007;10(6):1266–1276. doi: 10.1089/jpm.2007.0017.
    1. Davison SN. Integrating palliative care for patients with advanced chronic kidney disease: recent advances, remaining challenges. J Palliat Care. 2011;27(1):53–61.
    1. Oliver MJ, Garg AX, Blake PG, Johnson JF, Verrelli M, Zacharias JM, Pandeya S, Quinn RR. Impact of contraindications, barriers to self-care and support on incident peritoneal dialysis utilization. Nephrol Dial Transplant. 2010;25(8):2737–2744. doi: 10.1093/ndt/gfq085.
    1. Naylor MD, Brooten D, Campbell R, Jacobsen BS, Mezey MD, Pauly MV, Schwartz JS. Comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA. 1999;281(7):613–620. doi: 10.1001/jama.281.7.613.
    1. Drain M. Quality improvement in primary care and the importance of patient perceptions. J Ambul Care Manage. 2001;24(2):30–46. doi: 10.1097/00004479-200104000-00005.
    1. Kleefstra SM, Kool RB, Veldkamp CM, der Meer AC W-v, Mens MA, Blijham GH, de Haes JC. A core questionnaire for the assessment of patient satisfaction in academic hospitals in The Netherlands: development and first results in a nationwide study. Qual Saf Health Care. 2010;19(5):e24.

Source: PubMed

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