Educating Patients by Providing Timely Information Using Smartphone and Tablet Apps: Systematic Review

Thomas Timmers, Loes Janssen, Rudolf B Kool, Jan Am Kremer, Thomas Timmers, Loes Janssen, Rudolf B Kool, Jan Am Kremer

Abstract

Background: Patient education is a crucial element within health care. It is a known predictor for increased engagement in shared decision making, improved medication and treatment adherence, higher levels of satisfaction, and even better treatment outcomes. Unfortunately, often patients only remember a very limited amount of medical information. An important reason is that most patients are simply not capable of processing large amounts of new medical information in a short time. Apps for smartphones and tablets have the potential to actively educate patients by providing them with timely information through the use of push notifications.

Objective: The objective of this systematic review is to provide an overview of the effects of using smartphone and tablet apps to educate patients with timely education. Within this review, we focused on patients that receive their care in a hospital setting. We assessed the effects of the interventions on outcomes, such as patients' knowledge about their illness and treatment, adherence to treatment instructions and to medication usage, and satisfaction with the care they received.

Methods: A comprehensive search of MEDLINE (Medical Literature Analysis and Retrieval System Online), Embase, CINAHL (Cumulative Index to Nursing and Allied Health Literature), and Web of Science was conducted. Randomized controlled trials (RCTs) published between January 2015 and November 2019 were eligible for inclusion. Two reviewers independently searched and screened articles, assessed study quality and risk of bias, and extracted the data. Due to the heterogeneity of populations, interventions, and outcomes, a meta-analysis was not deemed appropriate. Instead, a narrative synthesis is presented.

Results: A total of 21 RCTs with 4106 participants were included. Compared to usual care, overall effectiveness of the interventions was demonstrated in 69% of the outcomes. Effectiveness increased to 82% when the intervention had a duration shorter than one month and increased to 78% when the intervention provided at least one push notification per week. The interventions showed the highest effects on satisfaction with information, adherence to treatment instructions and to medication usage, clinical outcomes, and knowledge.

Conclusions: This review demonstrates that educating patients with timely medical information through their smartphones or tablets improves their levels of knowledge, medication or treatment adherence, satisfaction, and clinical outcomes, as well as having a positive effect on health care economics. These effects are most pronounced in interventions with a short duration (ie, less than a month) and with a high frequency of messages to patients (ie, once per week or more). With the knowledge that patient education is a predictor for improved outcomes and the fact that patients have obvious difficulties processing large amounts of new medical information, we suggest incorporating the delivery of timely information through smartphone and tablet apps within current medical practices.

Keywords: eHealth; mobile phone; patient education; push notification; self-care; self-management; smartphone; tablet computer; timely education; timely information.

Conflict of interest statement

Conflicts of Interest: None declared.

©Thomas Timmers, Loes Janssen, Rudolf B Kool, Jan AM Kremer. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 13.04.2020.

Figures

Figure 1
Figure 1
PRISMA (Preferred Reported Items for Systematic Reviews and Meta-Analyses) flowchart. RCT: randomized controlled trial.
Figure 2
Figure 2
Level of risk of bias, per study, per domain.
Figure 3
Figure 3
Risk of bias presented as the percentage of studies with low risk, some concerns, or high risk, scored for the different domains of bias.

References

    1. Stacey D, Légaré F, Lewis K, Barry MJ, Bennett CL, Eden KB, Holmes-Rovner M, Llewellyn-Thomas H, Lyddiatt A, Thomson R, Trevena L. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. 2017 Apr 12;4:CD001431. doi: 10.1002/14651858.CD001431.pub5.
    1. Dineen-Griffin S, Garcia-Cardenas V, Williams K, Benrimoj SI. Helping patients help themselves: A systematic review of self-management support strategies in primary health care practice. PLoS One. 2019;14(8):e0220116. doi: 10.1371/journal.pone.0220116.
    1. Kessels RPC. Patients' memory for medical information. J R Soc Med. 2003 May;96(5):219–222. doi: 10.1258/jrsm.96.5.219.
    1. Khaleel I, Wimmer BC, Peterson GM, Zaidi ST, Roehrer E, Cummings E, Lee K. Health information overload among health consumers: A scoping review. Patient Educ Couns. 2020 Jan;103(1):15–32. doi: 10.1016/j.pec.2019.08.008.
    1. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration. BMJ. 2009 Jul 21;339:b2700. doi: 10.1136/bmj.b2700.
    1. Sterne JA, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng H, Corbett MS, Eldridge SM, Emberson JR, Hernán MA, Hopewell S, Hróbjartsson A, Junqueira DR, Jüni P, Kirkham JJ, Lasserson T, Li T, McAleenan A, Reeves BC, Shepperd S, Shrier I, Stewart LA, Tilling K, White IR, Whiting PF, Higgins JP. RoB 2: A revised tool for assessing risk of bias in randomised trials. BMJ. 2019 Aug 28;366:l4898. doi: 10.1136/bmj.l4898.
    1. Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd edition. New York, NY: Taylor & Francis Inc; 1988.
    1. Perry TT, Marshall A, Berlinski A, Rettiganti M, Brown RH, Randle SM, Luo C, Bian J. Smartphone-based vs paper-based asthma action plans for adolescents. Ann Allergy Asthma Immunol. 2017 Mar;118(3):298–303. doi: 10.1016/j.anai.2016.11.028.
    1. Kang X, Zhao L, Leung F, Luo H, Wang L, Wu J, Guo X, Wang X, Zhang L, Hui N, Tao Q, Jia H, Liu Z, Chen Z, Liu J, Wu K, Fan D, Pan Y, Guo X. Delivery of instructions via mobile social media app increases quality of bowel preparation. Clin Gastroenterol Hepatol. 2016 Mar;14(3):429–435.e3. doi: 10.1016/j.cgh.2015.09.038.
    1. Timmers T, Janssen L, van der Weegen W, Das D, Marijnissen W, Hannink G, van der Zwaard BC, Plat A, Thomassen B, Swen J, Kool RB, Lambers Heerspink FO. The effect of an app for day-to-day postoperative care education on patients with total knee replacement: Randomized controlled trial. JMIR Mhealth Uhealth. 2019 Oct 21;7(10):e15323. doi: 10.2196/15323.
    1. van der Meij E, Anema JR, Leclercq WK, Bongers MY, Consten EC, Schraffordt Koops SE, van de Ven PM, Terwee CB, van Dongen JM, Schaafsma FG, Meijerink WJ, Bonjer HJ, Huirne JA. Personalised perioperative care by e-health after intermediate-grade abdominal surgery: A multicentre, single-blind, randomised, placebo-controlled trial. Lancet. 2018 Jul 07;392(10141):51–59. doi: 10.1016/S0140-6736(18)31113-9.
    1. Timmers T, Janssen L, Pronk Y, van der Zwaard BC, Koëter S, van Oostveen D, de Boer S, Kremers K, Rutten S, Das D, van Geenen RC, Koenraadt KL, Kusters R, van der Weegen W. Assessing the efficacy of an educational smartphone or tablet app with subdivided and interactive content to increase patients' medical knowledge: Randomized controlled trial. JMIR Mhealth Uhealth. 2018 Dec 21;6(12):e10742. doi: 10.2196/10742.
    1. Hardt S, Schulz MR, Pfitzner T, Wassilew G, Horstmann H, Liodakis E, Weber-Spickschen TS. Improved early outcome after TKA through an app-based active muscle training programme: A randomized-controlled trial. Knee Surg Sports Traumatol Arthrosc. 2018 Nov;26(11):3429–3437. doi: 10.1007/s00167-018-4918-2.
    1. Van Reijen M, Vriend I, Zuidema V, van Mechelen W, Verhagen EA. The "Strengthen your ankle" program to prevent recurrent injuries: A randomized controlled trial aimed at long-term effectiveness. J Sci Med Sport. 2017 Jun;20(6):549–554. doi: 10.1016/j.jsams.2016.12.001.
    1. Lakshminarayana R, Wang D, Burn D, Chaudhuri KR, Galtrey C, Guzman NV, Hellman B, James B, Pal S, Stamford J, Steiger M, Stott RW, Teo J, Barker RA, Wang E, Bloem BR, van der Eijk M, Rochester L, Williams A. Using a smartphone-based self-management platform to support medication adherence and clinical consultation in Parkinson's disease. NPJ Parkinsons Dis. 2017;3:2. doi: 10.1038/s41531-016-0003-z.
    1. Asklund I, Nyström E, Sjöström M, Umefjord G, Stenlund H, Samuelsson E. Mobile app for treatment of stress urinary incontinence: A randomized controlled trial. Neurourol Urodyn. 2017 Jun;36(5):1369–1376. doi: 10.1002/nau.23116.
    1. Johnston N, Bodegard J, Jerström S, Åkesson J, Brorsson H, Alfredsson J, Albertsson PA, Karlsson J, Varenhorst C. Effects of interactive patient smartphone support app on drug adherence and lifestyle changes in myocardial infarction patients: A randomized study. Am Heart J. 2016 Aug;178:85–94. doi: 10.1016/j.ahj.2016.05.005.
    1. Lorenzo-Zúñiga V, Moreno de Vega V, Marín I, Barberá M, Boix J. Improving the quality of colonoscopy bowel preparation using a smart phone application: A randomized trial. Dig Endosc. 2015 Jul;27(5):590–595. doi: 10.1111/den.12467.
    1. Mata J, Pecorelli N, Kaneva P, Moldoveanu D, Gosselin-Tardiff A, Alhashemi M, Robitaille S, Balvardi S, Lee L, Stein BL, Liberman S, Charlebois P, Fiore JF, Feldman LS. A mobile device application (app) to improve adherence to an enhanced recovery program for colorectal surgery: A randomized controlled trial. Surg Endosc. 2020 Feb;34(2):742–751. doi: 10.1007/s00464-019-06823-w.
    1. Widmer RJ, Allison TG, Lennon R, Lopez-Jimenez F, Lerman LO, Lerman A. Digital health intervention during cardiac rehabilitation: A randomized controlled trial. Am Heart J. 2017 Jun;188:65–72. doi: 10.1016/j.ahj.2017.02.016.
    1. Lee H, Ghebre R, Le C, Jang YJ, Sharratt M, Yee D. Mobile phone multilevel and multimedia messaging intervention for breast cancer screening: Pilot randomized controlled trial. JMIR Mhealth Uhealth. 2017 Nov 07;5(11):e154. doi: 10.2196/mhealth.7091.
    1. Wang S, Wang Q, Yao J, Zhao S, Wang L, Li Z, Bai Y. Effect of WeChat and short message service on bowel preparation: An endoscopist-blinded, randomized controlled trial. Eur J Gastroenterol Hepatol. 2019 Feb;31(2):170–177. doi: 10.1097/MEG.0000000000001303.
    1. Li C, Huang S, Su X, Zhang T, Jiang K. Monitoring of home recovery using the 317-nursing mobile application following day-case surgery in children: Perspectives from both nurses and patients. Medicine (Baltimore) 2019 Aug;98(31):e16639. doi: 10.1097/MD.0000000000016639. doi: 10.1097/MD.0000000000016639.
    1. Jeon SC, Kim JH, Kim SJ, Kwon HJ, Choi YJ, Jung K, Kim SE, Moon W, Park MI, Park SJ. Effect of sending educational video clips via smartphone mobile messenger on bowel preparation before colonoscopy. Clin Endosc. 2019 Jan;52(1):53–58. doi: 10.5946/ce.2018.072. doi: 10.5946/ce.2018.072.
    1. Guo Y, Chen Y, Lane DA, Liu L, Wang Y, Lip GY. Mobile health technology for atrial fibrillation management integrating decision support, education, and patient involvement: mAF App trial. Am J Med. 2017 Dec;130(12):1388–1396.e6. doi: 10.1016/j.amjmed.2017.07.003.
    1. Najafi Ghezeljeh T, Sharifian S, Nasr Isfahani M, Haghani H. Comparing the effects of education using telephone follow-up and smartphone-based social networking follow-up on self-management behaviors among patients with hypertension. Contemp Nurse. 2018;54(4-5):362–373. doi: 10.1080/10376178.2018.1441730.
    1. Alanzi T, Bah S, Alzahrani S, Alshammari S, Almunsef F. Evaluation of a mobile social networking application for improving diabetes type 2 knowledge: An intervention study using WhatsApp. J Comp Eff Res. 2018 Sep;7(9):891–899. doi: 10.2217/cer-2018-0028.
    1. Sharara AI, Chalhoub JM, Beydoun M, Shayto RH, Chehab H, Harb AH, Mourad FH, Sarkis FS. A customized mobile application in colonoscopy preparation: A randomized controlled trial. Clin Transl Gastroenterol. 2017 Jan 05;8(1):e211. doi: 10.1038/ctg.2016.65.
    1. Grady PA, Gough LL. Self-management: A comprehensive approach to management of chronic conditions. Am J Public Health. 2014 Aug;104(8):e25–e31. doi: 10.2105/AJPH.2014.302041.
    1. Badawy SM, Kuhns LM. Texting and mobile phone app interventions for improving adherence to preventive behavior in adolescents: A systematic review. JMIR Mhealth Uhealth. 2017 Apr 19;5(4):e50. doi: 10.2196/mhealth.6837.
    1. Whitehead L, Seaton P. The effectiveness of self-management mobile phone and tablet apps in long-term condition management: A systematic review. J Med Internet Res. 2016 May 16;18(5):e97. doi: 10.2196/jmir.4883.
    1. Schoeppe S, Alley S, Van Lippevelde W, Bray NA, Williams SL, Duncan MJ, Vandelanotte C. Efficacy of interventions that use apps to improve diet, physical activity and sedentary behaviour: A systematic review. Int J Behav Nutr Phys Act. 2016 Dec 07;13(1):127. doi: 10.1186/s12966-016-0454-y.
    1. Morrison LG, Hargood C, Pejovic V, Geraghty AW, Lloyd S, Goodman N, Michaelides DT, Weston A, Musolesi M, Weal MJ, Yardley L. Correction: The effect of timing and frequency of push notifications on usage of a smartphone-based stress management intervention: An exploratory trial. PLoS One. 2018;13(5):e0198008. doi: 10.1371/journal.pone.0198008.
    1. Bashi N, Fatehi F, Fallah M, Walters D, Karunanithi M. Self-management education through mHealth: Review of strategies and structures. JMIR Mhealth Uhealth. 2018 Oct 19;6(10):e10771. doi: 10.2196/10771.
    1. Granja C, Janssen W, Johansen MA. Factors determining the success and failure of eHealth interventions: Systematic review of the literature. J Med Internet Res. 2018 May 01;20(5):e10235. doi: 10.2196/10235.
    1. Baker TB, Gustafson DH, Shah D. How can research keep up with eHealth? Ten strategies for increasing the timeliness and usefulness of eHealth research. J Med Internet Res. 2014 Feb 19;16(2):e36. doi: 10.2196/jmir.2925.
    1. Tønning ML, Kessing LV, Bardram JE, Faurholt-Jepsen M. Methodological challenges in randomized controlled trials on smartphone-based treatment in psychiatry: Systematic review. J Med Internet Res. 2019 Oct 27;21(10):e15362. doi: 10.2196/15362.

Source: PubMed

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