The prevalence and associated factors of symptomatic cervical Spondylosis in Chinese adults: a community-based cross-sectional study

Yanwei Lv, Wei Tian, Dafang Chen, Yajun Liu, Lifang Wang, Fangfang Duan, Yanwei Lv, Wei Tian, Dafang Chen, Yajun Liu, Lifang Wang, Fangfang Duan

Abstract

Background: Cervical spondylosis adversely affects life quality for its heavy disease burden. The report on the community-based prevalence and associated factors of cervical spondylosis is rare, especially in Chinese population. Whether prevention is needed and how to prevent it is not clear. This study aims to explore its prevalence and related lifestyle factors and provide evidence on prevention of cervical spondylosis.

Methods: A community-based multistage cross-sectional survey of six communities from the Chinese population was conducted. A face-to-face interview was conducted to obtain individual information, and prevalence was calculated. Single-factor analysis and multivariable logistic regressions were used to explore the associated factors in total and subgroup populations.

Results: A total of 3859 adults were analyzed. The prevalence of cervical spondylosis was 13.76%, although it differed significantly among the urban, suburban, and rural populations (13.07%, 15.97%, and 12.25%, respectively). Moreover, it was higher in females than in males (16.51% vs 10.49%). The prevalence among different age groups had an inverted U shape. The highest prevalence was in the age group from 45 to 60 years old. The associated factors differed by subgroups. There were positive associations between engaging in mental work, high housework intensity, and sleep duration of less than 7 h/day with cervical spondylosis. Going to work on foot was a negative factor of cervical spondylosis in the total population. For people aged less than 30 years, keeping the same work posture for 1-2.9 h/day was a special related factor. Exposure to vibration was an associated factor for females aged 45-60 years. Menopause was a special related factor for women.

Conclusions: Prevalence of cervical spondylosis was high in Chinese population. People younger than 60 years were the focus of prevention for cervical spondylosis. Moreover, the characters between male and female and among different age groups were different and required targeted interventions.

Keywords: Associated factors; Cervical spondylosis; Community-based; Cross-sectional study; Prevalence.

Conflict of interest statement

Ethics approval and consent to participate

The study protocol was approved by the institutional review board and the ethics committee of the Beijing Jishuitan Hospital, Beijing, China.

Written informed consent was obtained from each participant before the data was collected.

Consent for publication

Not applicable

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
The area specific prevalence of cervical spondylosis (I bar indicates prevalence ± standard error)
Fig. 2
Fig. 2
The age-specific prevalence of cervical spondylosis in different areas (I bar indicates prevalence ± standard error)
Fig. 3
Fig. 3
The sex-specific prevalence of cervical spondylosis in different areas (I bar indicates prevalence ± standard error)

References

    1. Xiong W, Li F, Guan H. Tetraplegia after thyroidectomy in a patient with cervical spondylosis: a case report and literature review. Medicine (Baltimore) 2015;94:e524. doi: 10.1097/MD.0000000000000524.
    1. Wang C, Tian F, Zhou Y, He W, Cai Z. The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. Clin Interv Aging. 2016;11:47–53.
    1. Stoffman MR, Roberts MS, King JJ. Cervical spondylotic myelopathy, depression, and anxiety: a cohort analysis of 89 patients. Neurosurgery. 2005;57:307–313. doi: 10.1227/01.NEU.0000166664.19662.43.
    1. Paanalahti K, Holm LW, Magnusson C, Carroll L, Nordin M, Skillgate E. The sex-specific interrelationship between spinal pain and psychological distress across time in the general population. Results from the Stockholm public health study. Spine Journal. 2014;14:1928–1935. doi: 10.1016/j.spinee.2013.11.017.
    1. Kelly JC, Groarke PJ, Butler JS, Poynton AR, O'Byrne JM. The natural history and clinical syndromes of degenerative cervical spondylosis. Adv Orthop. 2012;2012:393642. doi: 10.1155/2012/393642.
    1. Hartvigsen J, Christensen K, Frederiksen H. Back and neck pain exhibit many common features in old age: a population-based study of 4,486 Danish twins 70-102 years of age. Spine (Phila Pa 1976) 2004;29:576–580. doi: 10.1097/01.BRS.0000099394.18994.2F.
    1. Goode AP, Freburger J, Carey T. Prevalence, practice patterns, and evidence for chronic neck pain. Arthritis Care Res (Hoboken) 2010;62:1594–1601. doi: 10.1002/acr.20270.
    1. Vogt MT, Cawthon PM, Kang JD, Donaldson WF, Cauley JA, Nevitt MC. Prevalence of symptoms of cervical and lumbar stenosis among participants in the osteoporotic fractures in men study. Spine (Phila Pa 1976) 2006;31:1445–1451. doi: 10.1097/01.brs.0000219875.19688.a6.
    1. Klussmann A, Gebhardt H, Liebers F, Rieger MA. Musculoskeletal symptoms of the upper extremities and the neck: a cross-sectional study on prevalence and symptom-predicting factors at visual display terminal (VDT) workstations. BMC Musculoskelet Disord. 2008;9:96. doi: 10.1186/1471-2474-9-96.
    1. Fejer R, Kyvik KO, Hartvigsen J. The prevalence of neck pain in the world population: a systematic critical review of the literature. Eur Spine J. 2006;15:834–848. doi: 10.1007/s00586-004-0864-4.
    1. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386:743–800.
    1. Nagashima H, Dokai T, Hashiguchi H, Ishii H, Kameyama Y, Katae Y, et al. Clinical features and surgical outcomes of cervical spondylotic myelopathy in patients aged 80 years or older: a multi-center retrospective study. Eur Spine J. 2011;20:240–246. doi: 10.1007/s00586-010-1672-7.
    1. Hadjipavlou AG, Tzermiadianos MN, Bogduk N, Zindrick MR. The pathophysiology of disc degeneration: a critical review. J Bone Joint Surg Br. 2008;90:1261–1270. doi: 10.1302/0301-620X.90B10.20910.
    1. Kepler CK, Hilibrand AS. Management of adjacent segment disease after cervical spinal fusion. Orthop Clin North Am. 2012;43:53–62. doi: 10.1016/j.ocl.2011.08.003.
    1. Tian W, Lv Y, Liu Y, Xiao B, Han X. The high prevalence of symptomatic degenerative lumbar osteoarthritis in Chinese adults: a population-based study. Spine (Phila Pa 1976) 2014;39:1301–1310. doi: 10.1097/BRS.0000000000000396.
    1. Binder AI. Cervical spondylosis and neck pain. BMJ. 2007;334:527–531. doi: 10.1136/bmj.39127.608299.80.
    1. Yang W, Lu J, Weng J, Jia W, Ji L, Xiao J, et al. Prevalence of diabetes among men and women in China. N Engl J Med. 2010;362:1090–1101. doi: 10.1056/NEJMoa0908292.
    1. Schairer WW, Carrer A, Lu M, Hu SS. The increased prevalence of cervical spondylosis in patients with adult thoracolumbar spinal deformity. J Spinal Disord Tech. 2014;27:E305–E308. doi: 10.1097/BSD.0000000000000119.
    1. Oguntona SA. Cervical spondylosis in south west Nigerian farmers and female traders. Ann Afr Med. 2014;13:61–64. doi: 10.4103/1596-3519.129857.
    1. Labbafinejad Y, Imanizade Z, Danesh H. Ergonomic risk factors and their association with lower back and neck pain among pharmaceutical employees in Iran. Workplace Health & Safety. 2016;64:586–595. doi: 10.1177/2165079916655807.
    1. Andersen LL, Mortensen OS, Hansen JV, Burr H. A prospective cohort study on severe pain as a risk factor for long-term sickness absence in blue- and white-collar workers. Occup Environ Med. 2011;68:590–592. doi: 10.1136/oem.2010.056259.
    1. Mesas AE, Gonzalez AD, Mesas CE, de Andrade SM, Magro IS, Del LJ. The association of chronic neck pain, low back pain, and migraine with absenteeism due to health problems in Spanish workers. Spine (Phila Pa 1976) 2014;39:1243–1253. doi: 10.1097/BRS.0000000000000387.
    1. Okada E, Matsumoto M, Ichihara D, Chiba K, Toyama Y, Fujiwara H, et al. Aging of the cervical spine in healthy volunteers: a 10-year longitudinal magnetic resonance imaging study. Spine (Phila Pa 1976) 2009;34:706–712. doi: 10.1097/BRS.0b013e31819c2003.
    1. Singh S, Kumar D, Kumar S. Risk factors in cervical spondylosis. J Clin Orthop Trauma. 2014;5:221–226. doi: 10.1016/j.jcot.2014.07.007.
    1. Yang H, Haldeman S, Nakata A, Choi B, Delp L, Baker D. Work-related risk factors for neck pain in the US working population. Spine (Phila Pa 1976) 2015;40:184–192. doi: 10.1097/BRS.0000000000000700.
    1. Nordander C, Hansson GA, Ohlsson K, Arvidsson I, Balogh I, Stromberg U, et al. Exposure-response relationships for work-related neck and shoulder musculoskeletal disorders--analyses of pooled uniform data sets. Appl Ergon. 2016;55:70–84. doi: 10.1016/j.apergo.2016.01.010.
    1. Naidoo RN, Haq SA. Occupational use syndromes. Best Pract Res Clin Rheumatol. 2008;22:677–691. doi: 10.1016/j.berh.2008.04.001.
    1. Haldeman S, Carroll L, Cassidy JD. Findings from the bone and joint decade 2000 to 2010 task force on neck pain and its associated disorders. J Occup Environ Med. 2010;52:424–427. doi: 10.1097/JOM.0b013e3181d44f3b.
    1. Shelerud RA. Epidemiology of occupational low back pain. Clin Occup Environ Med. 2006;5:501–528.
    1. Murgia N, Dell'Omo M, Gambelunghe A, Folletti I, Muzi G, Abbritti G. Epidemiological evidence of possible musculoskeletal, cardiovascular and neoplastic effects in professional drivers. G Ital Med Lav Ergon. 2012;34:310–313.
    1. Murtezani A, Ibraimi Z, Sllamniku S, Osmani T, Sherifi S. Prevalence and risk factors for low back pain in industrial workers. Folia Med (Plovdiv) 2011;53:68–74.
    1. Palmer KT, Griffin M, Ntani G, Shambrook J, McNee P, Sampson M, et al. Professional driving and prolapsed lumbar intervertebral disc diagnosed by magnetic resonance imaging: a case-control study. Scand J Work Environ Health. 2012;38:577–581. doi: 10.5271/sjweh.3273.
    1. Milosavljevic S, Bagheri N, Vasiljev RM, McBride DI, Rehn B. Does daily exposure to whole-body vibration and mechanical shock relate to the prevalence of low back and neck pain in a rural workforce? Ann Occup Hyg. 2012;56:10–17.
    1. Teschke K, Nicol AM, Davies H, Ju S. Whole body vibrations and back disorders among motor vehicle drivers and heavy equipment operators: a review of the scientific evidence. Occup Hyg; 1999.
    1. Magora A. Investigation of the relation between low back pain and occupation. IMS Ind Med Surg. 1970;39:465–471.
    1. Chang Q, Wei F, Zhang L, Ju X, Zhu L, Huang C, et al. Effects of vibration in forced posture on biochemical bone metabolism indices, and morphometric and mechanical properties of the lumbar vertebra. PLoS One. 2013;8:e78640. doi: 10.1371/journal.pone.0078640.
    1. Toueg CW, Mac-Thiong JM, Grimard G, Parent S, Poitras B, Labelle H. Prevalence of spondylolisthesis in a population of gymnasts. Stud Health Technol Inform. 2010;158:132–137.
    1. Triantafillou KM, Lauerman W, Kalantar SB. Degenerative disease of the cervical spine and its relationship to athletes. Clin Sports Med. 2012;31:509–520. doi: 10.1016/j.csm.2012.03.009.
    1. Chang SK, Tominaga GT, Wong JH, Weldon EJ, Kaan KT. Risk factors for water sports-related cervical spine injuries. J Trauma. 2006;60:1041–1046. doi: 10.1097/01.ta.0000218256.39295.8f.
    1. Rastogi R, Bendore P. Effect of naturopathy treatments and yogic practices on cervical Spondylosis--a case report. Indian J Physiol Pharmacol. 2015;59:442–445.
    1. Shakoor MA, Ahmed MS, Kibria G, Khan AA, Mian MA, Hasan SA, et al. Effects of cervical traction and exercise therapy in cervical spondylosis. Bangladesh Med Res Counc Bull. 2002;28:61–69.
    1. Calleja-Agius J, Muscat-Baron Y, Brincat MP. Estrogens and the intervertebral disc. Menopause Int. 2009;15:127–130. doi: 10.1258/mi.2009.009016.
    1. Lou C, Chen HL, Feng XZ, Xiang GH, Zhu SP, Tian NF, et al. Menopause is associated with lumbar disc degeneration: a review of 4230 intervertebral discs. Climacteric. 2014;17:700–704. doi: 10.3109/13697137.2014.933409.
    1. Wang YX, Griffith JF. Menopause causes vertebral endplate degeneration and decrease in nutrient diffusion to the intervertebral discs. Med Hypotheses. 2011;77:18–20. doi: 10.1016/j.mehy.2011.03.014.
    1. Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Minamide A, et al. Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama spine study. Osteoarthr Cartil. 2014;22:104–110. doi: 10.1016/j.joca.2013.10.019.
    1. Fanuele JC, Abdu WA, Hanscom B, Weinstein JN. Association between obesity and functional status in patients with spine disease. Spine (Phila Pa 1976) 2002;27:306–312. doi: 10.1097/00007632-200202010-00021.
    1. Ricart W, Lopez J, Mozas J, Pericot A, Sancho MA, Gonzalez N, et al. Body mass index has a greater impact on pregnancy outcomes than gestational hyperglycaemia. Diabetologia. 2005;48:1736–1742. doi: 10.1007/s00125-005-1877-1.
    1. Rannou F, Corvol MT, Hudry C, Anract P, Dumontier MF, Tsagris L, et al. Sensitivity of anulus fibrosus cells to interleukin 1 beta. Comparison with articular chondrocytes Spine (Phila Pa 1976) 2000;25:17–23. doi: 10.1097/00007632-200001010-00005.
    1. Inoue N, Espinoza OA. Biomechanics of intervertebral disk degeneration. Orthop Clin North Am. 2011;42:487–499. doi: 10.1016/j.ocl.2011.07.001.
    1. Cote P, van der Velde G, Cassidy JD, Carroll LJ, Hogg-Johnson S, Holm LW, et al. The burden and determinants of neck pain in workers: results of the bone and joint decade 2000-2010 task force on neck pain and its associated disorders. J Manip Physiol Ther. 2009;32:S70–S86. doi: 10.1016/j.jmpt.2008.11.012.

Source: PubMed

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