Comparison of Different Disease-Specific Health-Related Quality of Life Measurements in Patients with Long-Term Noninvasive Ventilation

Toru Oga, Hiroyuki Taniguchi, Hideo Kita, Tomomasa Tsuboi, Keisuke Tomii, Morihide Ando, Eiji Kojima, Hiromi Tomioka, Yoshio Taguchi, Yusuke Kaji, Ryoji Maekura, Toru Hiraga, Naoki Sakai, Tomoki Kimura, Michiaki Mishima, Wolfram Windisch, Kazuo Chin, Toru Oga, Hiroyuki Taniguchi, Hideo Kita, Tomomasa Tsuboi, Keisuke Tomii, Morihide Ando, Eiji Kojima, Hiromi Tomioka, Yoshio Taguchi, Yusuke Kaji, Ryoji Maekura, Toru Hiraga, Naoki Sakai, Tomoki Kimura, Michiaki Mishima, Wolfram Windisch, Kazuo Chin

Abstract

Background: Two disease-specific questionnaires have been developed to assess health-related quality of life (HRQL) in patients with chronic respiratory failure: the Severe Respiratory Insufficiency (SRI) Questionnaire and the Maugeri Respiratory Failure (MRF) Questionnaire. We aimed to compare the characteristics of the SRI, MRF-26, and St. George's Respiratory Questionnaire (SGRQ) for use in patients with home noninvasive ventilation (NIV).

Methods: Fifty-six outpatients receiving long-term NIV were recruited and underwent assessments of pulmonary function, arterial blood gas, HRQL, dyspnea, and psychological status.

Results: Correlations of the SRI and MRF-26 with the SGRQ were modest. While pulmonary function was weakly related to only some domains of the SRI and MRF-26, the modified Medical Research Council (mMRC) dyspnea scale and Hospital Anxiety and Depression Scale (HADS) were significantly related to all domains of the SRI and MRF-26. Multiple regression analyses showed that HADS depression and mMRC accounted for 34% and 27% of the variance in the SRI, 24% and 37% in the MRF-26, and 17% and 46% in the SGRQ, respectively.

Conclusions: The SRI and MRF-26 were reliable questionnaires for patients receiving long-term NIV. Dyspnea and psychological status were their main common determinants. The SRI covers more psychological health impairments than the MRF. This trial is registered with ClinicalTrials.gov Identifier: NCT00905476.

References

    1. Jones P. W., Quirk F. H., Baveystock C. M., Littlejohns P. A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire. The American Review of Respiratory Disease. 1992;145(6):1321–1327. doi: 10.1164/ajrccm/145.6.1321.
    1. Swigris J. J., Esser D., Conoscenti C. S., Brown K. K. The psychometric properties of the St George's Respiratory Questionnaire (SGRQ) in patients with idiopathic pulmonary fibrosis: a literature review. Health and Quality of Life Outcomes. 2014;12(1, article 124) doi: 10.1186/s12955-014-0124-1.
    1. Pasipanodya J. G., Miller T. L., Vecino M., et al. Using the St. George Respiratory Questionnaire to ascertain health quality in persons with treated pulmonary tuberculosis. Chest. 2007;132(5):1591–1598. doi: 10.1378/chest.07-0755.
    1. Carone M., Bertolotti G., Anchisi F., Zotti A. M., Donner C. F., Jones P. W. Analysis of factors that characterize health impairment in patients with chronic respiratory failure. European Respiratory Journal. 1999;13(6):1293–1300.
    1. Windisch W., Freidel K., Schucher B., et al. The Severe Respiratory Insufficiency (SRI) Questionnaire: a specific measure of health-related quality of life in patients receiving home mechanical ventilation. Journal of Clinical Epidemiology. 2003;56(8):752–759. doi: 10.1016/S0895-4356(03)00088-X.
    1. Duiverman M. L., Wempe J. B., Bladder G., Kerstjens H. A. M., Wijkstra P. J. Health-related quality of life in COPD patients with chronic respiratory failure. European Respiratory Journal. 2008;32(2):379–386. doi: 10.1183/09031936.00163607.
    1. Struik F. M., Kerstjens H. A. M., Bladder G., et al. The Severe Respiratory Insufficiency Questionnaire scored best in the assessment of health-related quality of life in chronic obstructive pulmonary disease. Journal of Clinical Epidemiology. 2013;66(10):1166–1174. doi: 10.1016/j.jclinepi.2013.04.013.
    1. Guyatt G. H., Berman L. B., Townsend M., Pugsley S. O., Chambers L. W. A measure of quality of life for clinical trials in chronic lung disease. Thorax. 1987;42(10):773–778. doi: 10.1136/thx.42.10.773.
    1. Oga T., Taniguchi H., Kita H., et al. Validation of the Japanese Severe Respiratory Insufficiency Questionnaire in hypercapnic patients with noninvasive ventilation. Respiratory Investigation. 2017;55:166–172.
    1. Oga T., Taniguchi H., Kita H., et al. Analysis of the relationship between health status and mortality in hypercapnic patients with noninvasive ventilation. The Clinical Respiratory Journal. 2015 doi: 10.1111/crj.12415.
    1. Oga T., Nishimura K., Tsukino M., Sato S., Hajiro T. Analysis of the factors related to mortality in chronic obstructive pulmonary disease: role of exercise capacity and health status. American Journal of Respiratory and Critical Care Medicine. 2003;167:544–549.
    1. Windisch W., Budweiser S., Heinemann F., Pfeifer M., Rzehak P. The Severe Respiratory Insufficiency Questionnaire was valid for COPD patients with severe chronic respiratory failure. Journal of Clinical Epidemiology. 2008;61(8):848–853. doi: 10.1016/j.jclinepi.2007.09.009.
    1. Vidotto G., Carone M., Jones P. W., Salini S., Bertolotti G. Maugeri Respiratory Failure questionnaire reduced form: a method for improving the questionnaire using the Rasch model. Disability and Rehabilitation. 2007;29(13):991–998. doi: 10.1080/09638280600926678.
    1. National Institute for Clinical Excellence (NICE) Chronic obstructive pulmonary disease. National clinical guideline on management of chronic obstructive pulmonary disease in adults in primary and secondary care. Thorax. 2004;59(supplement 1):1–232.
    1. Zigmond A. S., Snaith R. P. The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica. 1983;67(6):361–370. doi: 10.1111/j.1600-0447.1983.tb09716.x.
    1. Köhnlein T., Windisch W., Köhler D., et al. Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. The Lancet Respiratory Medicine. 2014;2(9):698–705. doi: 10.1016/s2213-2600(14)70153-5.
    1. Jones P. W. Activity limitation and quality of life in COPD. COPD. 2007;4(3):273–278. doi: 10.1080/15412550701480265.
    1. Walterspacher S., July J., Kohlhäufl M., Rzehak P., Windisch W. The severe respiratory insufficiency questionnaire for subjects with COPD with long-term oxygen therapy. Respiratory Care. 2016;61:1186–1191.

Source: PubMed

Sponsorit ja yhteistyökumppanit

Sairaudet

Huumeiden interventiot

3
Tilaa