Trunk versus extremity adiposity and cardiometabolic risk factors in white and African American adults

Gang Hu, Claude Bouchard, George A Bray, Frank L Greenway, William D Johnson, Robert L Newton Jr, Eric Ravussin, Donna H Ryan, Peter T Katzmarzyk, Gang Hu, Claude Bouchard, George A Bray, Frank L Greenway, William D Johnson, Robert L Newton Jr, Eric Ravussin, Donna H Ryan, Peter T Katzmarzyk

Abstract

Objective: To determine contributions of trunk and extremity adiposity to cardiometabolic risk factors (blood pressure, fasting blood glucose, HDL cholesterol, and triglycerides) among white and African American adults.

Research design and methods: The sample consisted of 1,129 white women, 779 African American women, 1,012 white men, and 300 African American men.

Results: Higher trunk adiposity was significantly associated with an increased risk of having two or more cardiometabolic risk factors among African American and white men and women. After adjustment for trunk and arm adiposity, higher leg adiposity was significantly associated with a decreased risk of having two or more cardiometabolic risk factors among white men and women and African American women.

Conclusions: In contrast with adverse risk with high trunk adiposity, high leg adiposity is associated with a decreased risk of having two or more cardiometabolic risk factors in both African American and white adults.

Figures

Figure 1
Figure 1
ORs (95% CI) for having two or more abnormal risk factors in subjects classified in the second and third sex- and ethnic-specific tertiles of trunk adiposity, arm adiposity, and leg adiposity compared with those in the first tertile (reference group, OR = 1.0) among African American and white men and women. These were adjusted for age, year of testing, smoking status, menopausal status (in women), trunk adiposity, arm adiposity, and leg adiposity, other than the variable in the analytic model. *The first tertile is the reference (OR = 1.0); †test is for trend across tertiles of adiposity. (A high-quality color representation of this figure is available in the online issue.)

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