Epidemiology of Nontuberculous Mycobacterial Infection, South Korea, 2007-2016

Hyewon Lee, Woojae Myung, Won-Jung Koh, Seong Mi Moon, Byung Woo Jhun, Hyewon Lee, Woojae Myung, Won-Jung Koh, Seong Mi Moon, Byung Woo Jhun

Abstract

The prevalence and incidence of nontuberculous mycobacterial (NTM) infections increased in South Korea from 2007 to 2016. Annual prevalence of NTM infection increased to 39.6 cases/100,000 population in 2016 and annual incidence to 19.0 cases/100,000 population. Overall prevalence for the study period was higher in the elderly, in females, and in cities.

Keywords: South Korea; bacteria; epidemiology; mycobacteria; nontuberculous mycobacteria; tuberculosis and other mycobacteria.

Figures

Figure 1
Figure 1
Annual prevalence (total no. cases/100,000 population) and incidence (no. new cases/100,000/year) of nontuberculous mycobacterial infection, adjusted for age and sex, South Korea, 2007–2016.
Figure 2
Figure 2
Overall period prevalence (total no. cases/100,000 population) of nontuberculous mycobacterial infection, by age group (A) and by age group and sex (B), South Korea, 2007–2016.

References

    1. Prevots DR, Marras TK. Epidemiology of human pulmonary infection with nontuberculous mycobacteria: a review. Clin Chest Med. 2015;36:13–34. 10.1016/j.ccm.2014.10.002
    1. Ko RE, Moon SM, Ahn S, Jhun BW, Jeon K, Kwon OJ, et al. Changing epidemiology of nontuberculous mycobacterial lung diseases in a tertiary referral hospital in Korea between 2001 and 2015. J Korean Med Sci. 2018;33:e65. 10.3346/jkms.2018.33.e65
    1. Cheol Seong S, Kim YY, Khang YH, Heon Park J, Kang HJ, Lee H, et al. Data Resource Profile: The National Health Information Database of the National Health Insurance Service in South Korea. Int J Epidemiol. 2017;46:799–800.
    1. Ringshausen FC, Wagner D, de Roux A, Diel R, Hohmann D, Hickstein L, et al. Prevalence of nontuberculous mycobacterial pulmonary disease, Germany, 2009–2014. Emerg Infect Dis. 2016;22:1102–5. 10.3201/eid2206.151642
    1. Adjemian J, Olivier KN, Seitz AE, Holland SM, Prevots DR. Prevalence of nontuberculous mycobacterial lung disease in U.S. Medicare beneficiaries. Am J Respir Crit Care Med. 2012;185:881–6. 10.1164/rccm.201111-2016OC
    1. Henkle E, Hedberg K, Schafer S, Novosad S, Winthrop KL. Population-based incidence of pulmonary nontuberculous mycobacterial disease in Oregon 2007 to 2012. Ann Am Thorac Soc. 2015;12:642–7. 10.1513/AnnalsATS.201412-559OC
    1. Morimoto K, Iwai K, Uchimura K, Okumura M, Yoshiyama T, Yoshimori K, et al. A steady increase in nontuberculous mycobacteriosis mortality and estimated prevalence in Japan. Ann Am Thorac Soc. 2014;11:1–8. 10.1513/AnnalsATS.201303-067OC
    1. Namkoong H, Kurashima A, Morimoto K, Hoshino Y, Hasegawa N, Ato M, et al. Epidemiology of pulmonary nontuberculous mycobacterial disease, Japan. Emerg Infect Dis. 2016;22:1116–7. 10.3201/eid2206.151086
    1. Adjemian J, Olivier KN, Seitz AE, Falkinham JO III, Holland SM, Prevots DR. Spatial clusters of nontuberculous mycobacterial lung disease in the United States. Am J Respir Crit Care Med. 2012;186:553–8. 10.1164/rccm.201205-0913OC
    1. Adjemian J, Frankland TB, Daida YG, Honda JR, Olivier KN, Zelazny A, et al. Epidemiology of nontuberculous mycobacterial lung disease and tuberculosis, Hawaii, USA. Emerg Infect Dis. 2017;23:439–47. 10.3201/eid2303.161827
    1. Olivier KN, Weber DJ, Wallace RJ Jr, Faiz AR, Lee JH, Zhang Y, et al.; Nontuberculous Mycobacteria in Cystic Fibrosis Study Group. Nontuberculous mycobacteria. I: multicenter prevalence study in cystic fibrosis. Am J Respir Crit Care Med. 2003;167:828–34. 10.1164/rccm.200207-678OC
    1. Mirsaeidi M, Machado RF, Garcia JG, Schraufnagel DE. Nontuberculous mycobacterial disease mortality in the United States, 1999-2010: a population-based comparative study. PLoS One. 2014;9:e91879. 10.1371/journal.pone.0091879
    1. Yohannes AM, Alexopoulos GS. Depression and anxiety in patients with COPD. Eur Respir Rev. 2014;23:345–9. 10.1183/09059180.00007813
    1. Prevots DR, Shaw PA, Strickland D, Jackson LA, Raebel MA, Blosky MA, et al. Nontuberculous mycobacterial lung disease prevalence at four integrated health care delivery systems. Am J Respir Crit Care Med. 2010;182:970–6. 10.1164/rccm.201002-0310OC
    1. Winthrop KL, Baxter R, Liu L, Varley CD, Curtis JR, Baddley JW, et al. Mycobacterial diseases and antitumour necrosis factor therapy in USA. Ann Rheum Dis. 2013;72:37–42. 10.1136/annrheumdis-2011-200690

Source: PubMed

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