The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma
American Brachytherapy Society - Ophthalmic Oncology Task Force. Electronic address: paulfinger@eyecancer.com, ABS – OOTF Committee, E Rand Simpson, Brenda Gallie, Normand Laperrierre, Akbar Beiki-Ardakani, Tero Kivelä, Virpi Raivio, Jorma Heikkonen, Laurence Desjardins, Remi Dendale, Alexandro Mazal, Norbert Bornfeld, Wolfgang Sauerwein, Dirk Flüehs, Lorenzo Brualla, Santosh G Honavar, Vijay Anand P Reddy, Shigenobu Suzuki, Naoya Murakami, Svetlana Saakyan, Vladimir Valskiy, Anush Amiryan, Stefan Seregard, Charlotta All-Eriksson, Lars Hjelmqvist, Göran Lundell, Georges Sinclair, Marie Lundell, Bertil Damato, R Doug Errington, Philip Mayles, Helen Mayles, Chris Bergstrom, Hans Grossniklaus, Ian Crocker, Elizabeth Butker, Matthew Wilson, Barrett Haik, Holger Geischen, Pradeep Patra, Jay Duker, John Mignano, Mark Rivard, Paul T Finger, Ekaterina Semenova, Walter Choi, Nina I Kalach, American Brachytherapy Society - Ophthalmic Oncology Task Force. Electronic address: paulfinger@eyecancer.com, ABS – OOTF Committee, E Rand Simpson, Brenda Gallie, Normand Laperrierre, Akbar Beiki-Ardakani, Tero Kivelä, Virpi Raivio, Jorma Heikkonen, Laurence Desjardins, Remi Dendale, Alexandro Mazal, Norbert Bornfeld, Wolfgang Sauerwein, Dirk Flüehs, Lorenzo Brualla, Santosh G Honavar, Vijay Anand P Reddy, Shigenobu Suzuki, Naoya Murakami, Svetlana Saakyan, Vladimir Valskiy, Anush Amiryan, Stefan Seregard, Charlotta All-Eriksson, Lars Hjelmqvist, Göran Lundell, Georges Sinclair, Marie Lundell, Bertil Damato, R Doug Errington, Philip Mayles, Helen Mayles, Chris Bergstrom, Hans Grossniklaus, Ian Crocker, Elizabeth Butker, Matthew Wilson, Barrett Haik, Holger Geischen, Pradeep Patra, Jay Duker, John Mignano, Mark Rivard, Paul T Finger, Ekaterina Semenova, Walter Choi, Nina I Kalach
Abstract
Purpose: To present the American Brachytherapy Society (ABS) guidelines for plaque brachytherapy of choroidal melanoma and retinoblastoma.
Methods and materials: An international multicenter Ophthalmic Oncology Task Force (OOTF) was assembled to include 47 radiation oncologists, medical physicists, and ophthalmic oncologists from 10 countries. The ABS-OOTF produced collaborative guidelines, based on their eye cancer-specific clinical experience and knowledge of the literature. This work was reviewed and approved by the ABS Board of Directors as well as within the journal's peer-reivew process.
Results: The ABS-OOTF reached consensus that ophthalmic plaque radiation therapy is best performed in subspecialty brachytherapy centers. Quality assurance, methods of plaque construction, and dosimetry should be consistent with the 2012 joint guidelines of the American Association of Physicists in Medicine and ABS. Implantation of plaque sources should be performed by subspecialty-trained surgeons. Although there exist select restrictions related to tumor size and location, the ABS-OOTF agreed that most melanomas of the iris, ciliary body, and choroid could be treated with plaque brachytherapy. The ABS-OOTF reached consensus that tumors with gross orbital extension and blind painful eyes and those with no light perception vision are unsuitable for brachytherapy. In contrast, only select retinoblastomas are eligible for plaque brachytherapy. Prescription doses, dose rates, treatment durations, and clinical methods are described.
Conclusions: Plaque brachytherapy is an effective eye and vision-sparing method to treat patients with intraocular tumors. Practitioners are encouraged to use ABS-OOTF guidelines to enhance their practice.
Keywords: ABS; Brachytherapy; Consensus; Guidelines; Melanoma; Methods; Plaque; Radiation; Retinoblastoma.
Copyright © 2014 American Brachytherapy Society. All rights reserved.
Source: PubMed