A retrospective cohort study to evaluate the impact of meaningful weight loss on fertility outcomes in an overweight population with infertility
Jonathan D Kort, Caitlin Winget, Sun H Kim, Ruth B Lathi, Jonathan D Kort, Caitlin Winget, Sun H Kim, Ruth B Lathi
Abstract
Objective: To determine if meaningful weight loss (≥10%) improved conception and live birth rates of overweight patients with infertility.
Design: A retrospective cohort study.
Setting: Academic medical center.
Patient(s): Overweight patients (body mass index ≥25 kg/m(2); n = 52) being treated for infertility and referred for weight loss counseling.
Intervention(s): Patients were given a "meaningful" weight loss goal of 10%. They were followed by an endocrinologist who provided diet and exercise recommendations, metabolic screening, and pharmacologic intervention when indicated.
Main outcome measure(s): Pregnancy rate, live birth rate, weight loss.
Result(s): Thirty-two percent of the patients achieved meaningful weight loss. Patients achieving meaningful weight loss had significantly higher conception (88% vs. 54%) and live birth rates (71% vs. 37%) than those who did not.
Conclusion(s): Weight loss improves live birth rates in overweight patients with infertility. Health care providers should incorporate weight loss counseling when caring for overweight patients who plan to conceive.
Keywords: BMI; Obesity; infertility; overweight; weight loss.
Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Source: PubMed