Repeated Daily Use of Dual-Light Antibacterial Photodynamic Therapy in Periodontal Disease-A Case Report

Katherina Trujiilo, Ismo T Räisänen, Timo Sorsa, Tommi Pätilä, Katherina Trujiilo, Ismo T Räisänen, Timo Sorsa, Tommi Pätilä

Abstract

Good oral hygiene at home is the foundation for optimal treatment response and long-term periodontal disease control. Antibacterial photodynamic therapy (aPDT) provides a very potent adjunctive treatment for plaque control. However, the literature regarding repeated aPDT use is sparse. aPDT has been a modality applied mainly in the dental office environment, and when applied once a year or every few months, the results have been usually disappointing. Recently, LED development has brought aPDT for repeated and practical use at home. We present the very positive results and clinical outcome of daily applied dual-light aPDT-technology treatment in conjunction with mechanical cleaning of a 78-year-old male patient with severe periodontal disease (Stage IV and Grade B).

Keywords: antibacterial photodynamic therapy; oral hygiene; periodontitis.

Conflict of interest statement

T.P. is a stock owner and founder of Koite Health Oy and a coinventor of patents US20210030874A1, WO2021023915A1, WO2020193870A1, and WO2019234308A1.

Figures

Figure 1
Figure 1
The dual-light aPDT device. (A) The packaging includes the effervescent ICG tablets (*) to be dissolved in 30 mL of water, for which a measuring cup (**) is available. A power source (***) provides electricity for the mouthguard-type light applicator. (B) The mouthpiece (*) is composed of 48 LED components (**) able to provide simultaneous 405 nm and 810 nm light. Symmetrically assembled LEDs provided light for both maxillary and mandibular dental arch. The button on the control unit provided a treatment time of 10 min (***). The glass contains dissolved mouth rinse.
Figure 2
Figure 2
Representation of the clinical situation on 26 April 2021. The white line describes the clinical attachment level and the blue color infected periodontal pockets. The red dots represent a positive result in bleeding on probing.
Figure 3
Figure 3
Representation of the clinical situation on 27 January 2022. The white line describes the clinical attachment level and the blue color plaque-infested periodontal pockets. The red dots represent a positive result in bleeding on probing. A total of eight teeth with a minimum of 4 mm pocket depths showed no pockets at all. In addition, the overall clinical attachment level improved significantly.
Figure 4
Figure 4
Representation of the clinical situation on 25 May 2022. The white line describes the clinical attachment level and the blue color infected periodontal pockets. The red dots represent a positive result in bleeding on probing.
Figure 5
Figure 5
(A) The timeline of the patient visits to the clinic. (B) The number of periodontal pocket depths (PPD)s of 4 mm, 5 mm, 6 mm, and 7 mm measured at the beginning of the study (26 April 2021) and during aPDT use at the maintenance visits (27 January 2022 and 25 May 2022).

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