Prevalence and risk factors of loneliness among patients with hematological malignancies

Junye Yu, Huanhuan Song, Junye Yu, Huanhuan Song

Abstract

To identify independent factors for predicting loneliness in patients with hematological malignancies. It is an observational cross-sectional study. 157 patients with hematologic malignancies were enrolled between March 2020 and May 2020. The sociodemographic characteristics and psychometric properties (coping styles, self-esteem, big 5 personality traits, and hope) were tested for correlation with loneliness. Multivariate hierarchical regression analysis was then utilized to identify independent risk factors for loneliness. The patients exhibited a mean global score of 36.25 that corresponded to a moderate degree of loneliness. The sociodemographic factors, including occupation, family earning, living areas, times of hospitalization, were significantly related to loneliness. In addition, the coping styles, levels of self-esteem, the big 5 personality traits, and levels of hope were significantly correlated with the degrees of loneliness. Furthermore, sociodemographic factors (occupation) and psychometric properties (coping styles and hope) were identified as independent predictors for loneliness in patients with hematological malignancies. Loneliness is highly prevalent in patients with hematological malignancies. Notably, occupation, times of hospitalization, family earning, coping styles, self-esteem, big 5 personality traits, and hope are all independent risk factors for loneliness.

Conflict of interest statement

The authors have no funding and conflicts of interest to disclose.

Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

References

    1. Velasquez MP, Bonifant CL, Gottschalk S. Redirecting T cells to hematological malignancies with bispecific antibodies. Blood. 2018;131:30–8.
    1. Zomerdijk N, Turner JM, Hill GR. Adult-related haematopoietic stem cell donor experiences and the provision of information and psychosocial support: a systematic literature review. Eur J Cancer Care (Engl). 2019;28:e12932.
    1. Oelofse D, Truter I. Incidence of haematological malignancies, Eastern Cape Province; South Africa, 2004-2013. Cancer Epidemiol. 2018;53:166–71.
    1. Torre LA, Bray F, Siegel RL, et al. . Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87–108.
    1. Sun YQ, Huang XJ. [The challenges and strategies for treatment of hematological malignancies in China]. Zhonghua Nei Ke Za Zhi. 2021;60:857–9.
    1. Drury Z, Ly T, Abraham J. Nephrotoxic effects of chemotherapeutic agents. Clin J Oncol Nurs. 2022;26:219–23.
    1. Kato J, Mori T, Suzuki T, et al. . Nosocomial BK polyomavirus infection causing hemorrhagic cystitis among patients with hematological malignancies after hematopoietic stem cell transplantation. Am J Transplant. 2017;17:2428–33.
    1. An H, Hu X, Shen Y, et al. . Analysis of nosocomial infection status and direct economic loss of hospitalized children with malignant tumor. Chinese Journal of Nosocomiology. 2018;28:2820–4.
    1. Yu J, Dong H, Song Y, et al. . Influencing factors of hope among Chinese patients with hematological malignancies from the perspective of positive psychology: a cross-sectional study. Cancer Nurs. 2022.
    1. Levy I, Sharf G, Norman S, et al. . The impact of COVID-19 on patients with hematological malignancies: the mixed-method analysis of an Israeli national survey. Support Care Cancer. 2021;29:7591–9.
    1. Karhe L, Kaunonen M. Patient experiences of loneliness: an evolutionary concept analysis. ANS Adv Nurs Sci. 2015;38:E21–34.
    1. Russell D, Peplau LA, Cutrona CE. The revised UCLA loneliness scale: concurrent and discriminant validity evidence. J Pers Soc Psychol. 1980;39:472–80.
    1. Donovan NJ, Wu Q, Rentz DM, et al. . Loneliness, depression and cognitive function in older U.S. adults. Int J Geriatr Psychiatry. 2017;32:564–73.
    1. Zhong BL, Chen SL, Tu X, et al. . Loneliness and cognitive function in older adults: findings from the Chinese longitudinal healthy longevity survey. J Gerontol B Psychol Sci Soc Sci. 2017;72:120–8.
    1. Ong AD, Uchino BN, Wethington E. Loneliness and health in older adults: a mini-review and synthesis. Gerontology. 2016;62:443–9.
    1. Diehl K, Jansen C, Ishchanova K, et al. . Loneliness at universities: determinants of emotional and social loneliness among students. Int J Environ Res Public Health. 2018;15:1865.
    1. Ying L, Yan Q, Shen X, et al. . Economic pressure and loneliness in migrant children in China: the mediating roles of parent-child communication and parental warmth. Child Psychiatry Hum Dev. 2019;50:142–9.
    1. Vassar M, Crosby JW. A reliability generalization study of coefficient alpha for the UCLA loneliness scale. J Pers Assess. 2008;90:601–7.
    1. Xie Y. Simplified coping style questionnaire. Chin Ment Health J. 1999;13:122–4.
    1. Ji Y, Yu X. The self-esteem scale, SES. Chin Ment Health J. 1999;7:318–20.
    1. Wang M, Dai X, Yao S. Chinese big five personality inventory brief version, CBF-PI-B. Chin Ment Health J. 2011;19:454–7.
    1. Zhao H, Wang J. The social support and hope of hemodialysis patients. Chin J Nurs. 2000;35:206–8.
    1. Deckx L, van den Akker M, Buntinx F. Risk factors for loneliness in patients with cancer: a systematic literature review and meta-analysis. Eur J Oncol Nurs. 2014;18:466–77.
    1. Vehling S, Oechsle K, Hartmann M, et al. . Perceived positive and negative life changes in testicular cancer survivors. Medicina (Kaunas). 2021;57:993.
    1. Van Beek FE, Wijnhoven LMA, Holtmaat K, et al. . Psychological problems among cancer patients in relation to healthcare and societal costs: a systematic review. Psychooncology. 2021;30:1801–35.
    1. Song B, Qiao X, Xu J. The relationship between living style and loneliness of the elderly in Beijing: analysis using logistic regression model. Chin J Gerontol. 2020;40:2645–9.
    1. Yu R. Study of loneliness of elderly in rural areas in Shandong Province of China. Shandong Univ. 2018:1–63.
    1. Liu Y, Zhou S. The relationship between self-esteem, social problem solving, or loneliness, and mobile phone dependence in the higher vocational college freshmen. Chin Ment Health J. 2019;27:777–80.

Source: PubMed

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