Effect of providing free glasses on children's educational outcomes in China: cluster randomized controlled trial

Xiaochen Ma, Zhongqiang Zhou, Hongmei Yi, Xiaopeng Pang, Yaojiang Shi, Qianyun Chen, Mirjam E Meltzer, Saskia le Cessie, Mingguang He, Scott Rozelle, Yizhi Liu, Nathan Congdon, Xiaochen Ma, Zhongqiang Zhou, Hongmei Yi, Xiaopeng Pang, Yaojiang Shi, Qianyun Chen, Mirjam E Meltzer, Saskia le Cessie, Mingguang He, Scott Rozelle, Yizhi Liu, Nathan Congdon

Abstract

Objective: To assess the effect of provision of free glasses on academic performance in rural Chinese children with myopia.

Design: Cluster randomized, investigator masked, controlled trial.

Setting: 252 primary schools in two prefectures in western China, 2012-13.

Participants: 3177 of 19,934 children in fourth and fifth grades (mean age 10.5 years) with visual acuity <6/12 in either eye without glasses correctable to >6/12 with glasses. 3052 (96.0%) completed the study.

Interventions: Children were randomized by school (84 schools per arm) to one of three interventions at the beginning of the school year: prescription for glasses only (control group), vouchers for free glasses at a local facility, or free glasses provided in class.

Main outcome measures: Spectacle wear at endline examination and end of year score on a specially designed mathematics test, adjusted for baseline score and expressed in standard deviations.

Results: Among 3177 eligible children, 1036 (32.6%) were randomized to control, 988 (31.1%) to vouchers, and 1153 (36.3%) to free glasses in class. All eligible children would benefit from glasses, but only 15% wore them at baseline. At closeout glasses wear was 41% (observed) and 68% (self reported) in the free glasses group, and 26% (observed) and 37% (self reported) in the controls. Effect on test score was 0.11 SD (95% confidence interval 0.01 to 0.21) when the free glasses group was compared with the control group. The adjusted effect of providing free glasses (0.10, 0.002 to 0.19) was greater than parental education (0.03, -0.04 to 0.09) or family wealth (0.01, -0.06 to 0.08). This difference between groups was significant, but was smaller than the prespecified 0.20 SD difference that the study was powered to detect.

Conclusions: The provision of free glasses to Chinese children with myopia improves children's performance on mathematics testing to a statistically significant degree, despite imperfect compliance, although the observed difference between groups was smaller than the study was originally designed to detect. Myopia is common and rarely corrected in this setting.Trial Registration Current Controlled Trials ISRCTN03252665.

Conflict of interest statement

Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: the free glasses used in this study were supplied by OneSight, Luxottica-China, and Essilor-China, producers of frames and lenses in China who also provided financial support for the study; the authors have no other financial relationships with any organisations that might have an interest in the submitted work in the previous three years; and no other relationships or activities that could appear to have influenced the submitted work.

© Ma et al 2014.

Figures

https://www.ncbi.nlm.nih.gov/pmc/articles/instance/4793841/bin/max019598.f1_default.jpg
Enrolment and progress of children through study

References

    1. Dimension of Disability in India, chapter 4, table 4.3 (b). 2013. .
    1. Resnikoff S, Pascolini D, Mariotti SP, Pokharel GP. Global magnitude of visual impairment caused by uncorrected refractive errors in 2004. Bull World Health Organ 2008;86:63-70.
    1. Krumholtz I. Results from a pediatric vision screening and its ability to predict academic performance. Optometry 2000;71:426-30.
    1. Atkinson J, Anker S, Nardini M, Braddick O, Hughes C, Rae S, Wattam-Bell J, Atkinson S. Infant vision screening predicts failure on motor and cognitive tests up to school age. Strabismus 2002;10:187-98.
    1. Williams WR, Latif AH, Hannington L, Watkins DR. Hyperopia and educational attainment in a primary school cohort. Arch Dis Childhood 2005;90:150-3.
    1. Roch-Levecq AC, Brody BL, Thomas RG, Brown SI. Ametropia, preschoolers’ cognitive abilities, and effects of spectacle correction. Arch Ophthalmol 2008;126:252-8.
    1. Johnson R, Nottingham D, Stratton R, Zaba J. The vision screening of academically and behaviorally at-risk pupils. J Behavioral Optom 1996;7:39-42.
    1. He M, Zeng J, Liu Y, Xu J, Pokharel GP, Ellwein LB. Refractive error and visual impairment in urban children in southern China. Invest Ophthalmol Vis Sci 2004;45:793-9.
    1. He M, Huang W, Zheng Y, Huang L, Ellwein LB. Refractive error and visual impairment in school children in rural southern China. Ophthalmology 2007;114:374-82.
    1. Murthy GV, Gupta SK, Ellwein LB, Muñoz SR, Pokharel GP, Sanga L, et al. Refractive error in children in an urban population in New Delhi. Invest Ophthalmol Vis Sci 2002;43:623-31.
    1. Congdon NG, Wang Y, Song Y, Choi K, Zhang M, Zhou Z, et al. Visual disability, visual function and myopia among rural Chinese secondary school children: the Xichang Pediatric Refractive Error Study (X-PRES) Report #1. Invest Ophthalmol Vis Sci 2008;49:2888-94.
    1. Wu HM, Seet B, Yap EP, Saw SM, Lim TH, Chia KS. Does education explain ethnic differences in myopia prevalence? A population-based study of young adult males in Singapore. Optom Vis Sci 2001;78:234-9.
    1. Congdon N, Zheng MW, Sharma A, Choi K, Song Y, Zhang MZ, et al. Prevalence and determinants of spectacle nonwear among rural Chinese secondary schoolchildren: the Xichang Pediatric Refractive Error Study report 3. Arch Ophthalmol 2008;126:1717-23.
    1. Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet 2012;379:1739-48.
    1. Sharma A, Congdon N, Patel M, Gilbert C. School-based approaches to correction of refractive error in children. Surv Ophthalmol 2012;57:272-83.
    1. Mathers M, Keyes M, Wright M. A review of the evidence on the effectiveness of children’s vision screening. Child Care Health Dev 2010;36:756-80.
    1. Baidu Encyclopedi. Article on Tianshui. 2013. . [In Chinese.]
    1. Wikipedia list of Chinese administrative divisions by GDP per capita in 2012. .
    1. Baidu Encyclopedia. Article on Yulin. 2013. . [In Chinese.]
    1. Congdon N, Patel N, Esteso P, Chikwembani F, Webber F, Msithini R, et al. The association between refractive cutoffs for spectacle provision and visual improvement among school-aged children in South Africa. Br J Ophthalmol 2008;92:13-8.
    1. Li L, Lam J, Lu Y, Ye Y, Lam DS, Gao Y, et al. Attitudes of students, parents, and teachers towards glasses use in rural China. Arch Ophthalmol 2010;128:759-65.
    1. Ferris FL 3rd, Kassoff A, Bresnick GH, Bailey I. New visual acuity charts for clinical research. Am J Ophthalmol 1982;94:91-6.
    1. Congdon N, Li L, Zhang M, Yang A, Gao Y, Griffiths S, et al. Randomized, controlled trial of an educational intervention to promote spectacle use in rural China: the See Well to Learn Well Study. Ophthalmology 2011;118:2343-50.
    1. Optimal Design Software for Multi-level and Longitudinal Research (Version 3.01). 2011. .
    1. Zou G. A modified Poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004;159:702-6.
    1. Royston P. Multiple imputation of missing values. Stata J 2004:227-41.
    1. Hill CJ, Bloom HS, Black R, Lipsey MW. Empirical benchmarks for interpreting effect sizes in research. MDRC working papers on research methodology. 2014. .
    1. Zhang MZ, Lv H, Gao Y, Griffiths S, Sharma A, Lam DSC, et al. Visual morbidity due to inaccurate spectacles among school-children in rural China: the See Well to Learn Well Project, Report #1. Invest Ophthalmol Vis Sci 2009;50:2011-7.
    1. Dirani M, Zhang X, Goh LK, Young TL, Lee P, Saw SM. The role of vision in academic school performance. Ophthalmic Epidemiol 2010;17:18-24.
    1. Survey in China shows a wide gap in income. 2014. .
    1. Liang X, Guo H, Jin C, Peng X, Zhang X. The effect of New Cooperative Medical Scheme on health outcomes and alleviating catastrophic health expenditure in China: a systematic review. PLoS One 2012;7:e40850.
    1. Li L, Lam J, Lu Y, Ye Y, Lam DS, Gao Y, et al. Attitudes of students, parents, and teachers towards glasses use in rural China. Arch Ophthalmol 2010;128:759-65.

Source: PubMed

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