Risk factors for urinary tract infection following incontinence surgery
Ingrid Nygaard, Linda Brubaker, Toby C Chai, Alayne D Markland, Shawn A Menefee, Larry Sirls, Gary Sutkin, Phillipe Zimmern, Amy Arisco, Liyuan Huang, Sharon Tennstedt, Anne Stoddard, Ingrid Nygaard, Linda Brubaker, Toby C Chai, Alayne D Markland, Shawn A Menefee, Larry Sirls, Gary Sutkin, Phillipe Zimmern, Amy Arisco, Liyuan Huang, Sharon Tennstedt, Anne Stoddard
Abstract
Introduction and hypothesis: The purpose of this study is to describe risk factors for post-operative urinary tract infection (UTI) the first year after stress urinary incontinence surgery.
Methods: Multivariable logistic regression analyses were performed on data from 1,252 women randomized in two surgical trials, Stress Incontinence Surgical Treatment Efficacy trial (SISTEr) and Trial Of Mid-Urethral Slings (TOMUS).
Results: Baseline recurrent UTI (rUTI; ≥3 in 12 months) increased the risk of UTI in the first 6 weeks in both study populations, as did sling procedure and self-catheterization in SISTEr, and bladder perforation in TOMUS. Baseline rUTI, UTI in the first 6 weeks, and PVR > 100 cc at 12 months were independent risk factors for UTI between 6 weeks and 12 months in the SISTEr population. Few (2.3-2.4%) had post-operative rUTI, precluding multivariable analysis. In women with pre-operative rUTI, successful surgery (negative cough stress test) at 1 year did not appear to decrease the risk of persistent rUTI.
Conclusions: Pre-operative rUTI is the strongest risk factor for post-operative UTI.
Source: PubMed