Role of Chest Ultrasound in Diagnosing and Follow-up of Pneumonia
Role of Chest Ultrasound in Diagnosing and Follow-up of Pneumonia. Prospective Comparison Between X-ray Chest Film in Two Planes and "Low-dose" Spiral Computed Tomography
The study of a large number of patients (at least 200 patients) from several European centres aims to investigate the value of chest ultrasound in diagnosing and checking the course of pneumonia as compared to a chest X-ray film in two planes and - in case of a controversial X-ray finding- as compared to low-dose CT.
An X-ray finding is regarded controversial, if infiltrates cannot be reliably excluded or not reliably represented and if a definite diagnosis is, thus, not possible. A low-dose CT is indicated even in case of a positive chest ultrasound and negative X-ray finding. Sonographic recording and characterization of pneumonic infiltrates is performed both at the time of diagnosing and in the further course under therapy.
Aperçu de l'étude
Statut
Les conditions
Description détaillée
The primary target criterion is
• Assessing the sensitivity of chest ultrasound in diagnosing pneumonia.
Secondary target criteria comprise
- Assessing specificity, negative and positive predictive value of chest ultrasound at the time of diagnosing,
- Characterizing pneumonic infiltrates at the time of diagnosing and further course,
- Describing the association between clinical, X-ray and sonographic findings in the course of pneumonia.
The tertiary target criterion includes
• Characterizing the range of pathogens detected by microbiological examination.
Type d'étude
Inscription (Réel)
Contacts et emplacements
Lieux d'étude
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Thüringen
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Jena, Thüringen, Allemagne, 07740
- Pneumology, Friedrich-Schiller University Jena
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Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
Accepte les volontaires sains
Sexes éligibles pour l'étude
Méthode d'échantillonnage
Population étudiée
La description
Inclusion Criteria:
Patients with clinically suspected CAP who received no antibiotic treatment yet
- Patients in whom a chest X-ray in 2 planes was already performed, can be included in the study, if chest ultrasound is performed within 24 hours after X-ray and if the X-ray finding is neither available to nor known to the examiner doing the ultrasound examination.
- Age > 18 years
- Patient's declaration of consent is available.
Exclusion Criteria:
- Patients with HAP
- Age <18 years
- Patients in whom the time difference between chest ultrasound and chest X-ray in 2 planes is more than 24 hours
- Patients whose X-ray findings are with the examiner doing the ultrasound or are known to him
- Pregnancy and lactation
- Missing declaration of consent by the patient.
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
Cohortes et interventions
Groupe / Cohorte |
|---|
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patients with suspected pneumonia
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Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Délai |
|---|---|
|
sensitivity of chest ultrasound in diagnosing pneumonia
Délai: baseline diagnostic
|
baseline diagnostic
|
Mesures de résultats secondaires
Mesure des résultats |
Délai |
|---|---|
|
Specificity
Délai: baseline diagnostic
|
baseline diagnostic
|
Collaborateurs et enquêteurs
Parrainer
Publications et liens utiles
Publications générales
- Copetti R, Cattarossi L. Ultrasound diagnosis of pneumonia in children. Radiol Med. 2008 Mar;113(2):190-8. doi: 10.1007/s11547-008-0247-8. Epub 2008 Apr 2. English, Italian.
- Reissig A, Kroegel C. Sonographic diagnosis and follow-up of pneumonia: a prospective study. Respiration. 2007;74(5):537-47. doi: 10.1159/000100427. Epub 2007 Feb 27.
- Reissig A, Mempel C, Schumacher U, Copetti R, Gross F, Aliberti S. Microbiological diagnosis and antibiotic therapy in patients with community-acquired pneumonia and acute COPD exacerbation in daily clinical practice: comparison to current guidelines. Lung. 2013 Jun;191(3):239-46. doi: 10.1007/s00408-013-9460-x. Epub 2013 Apr 6.
- Reissig A, Copetti R, Mathis G, Mempel C, Schuler A, Zechner P, Aliberti S, Neumann R, Kroegel C, Hoyer H. Lung ultrasound in the diagnosis and follow-up of community-acquired pneumonia: a prospective, multicenter, diagnostic accuracy study. Chest. 2012 Oct;142(4):965-972. doi: 10.1378/chest.12-0364.
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude
Achèvement primaire (Réel)
Achèvement de l'étude (Réel)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Estimation)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Estimation)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- 2055-06/07
- PD Dr. med. Angelika Reißig
- Phone: 00493641/ 9-32 41 28
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