Pre and Post Treatment Metabolomic Analysis of Leukemia: A Translational Clinical Trial of the Brown Cancer Center

Inclusion Criteria for Leukemia Subjects:

• Each of the criteria in the following section must be met in order for a patient to be eligible for enrollment.
• Only patients with clinically diagnosed or histologically diagnosed leukemia will be eligible to participate in this non-therapeutic study.
• All patients must have measurable quantities of leukemic blasts on peripheral blood detected with a CBC.
• No history of diabetes for the experimental group or the control group.
• Patients with known hepatitis C or HIV (AIDS) are excluded.
• Patients must be informed of the investigational nature of this study and sign and give written informed consent in accordance with institutional and federal guidelines.

Inclusion Criteria forHealthy Subjects:

• Subjects must have no known prior history of cancer or malignant blood disorders. -Where possible, follow up will be carried out to verify that no cancer has developed since the blood collection. This will be done by a phone call performed one month from sample to ask if new medical conditions have arisen.
• Subjects must have WBC, RBC, and platelet counts within normal range on CBC.
• Subjects with known hepatitis C or HIV (AIDS) are excluded.
• No history of Diabetes
• At least 30 years of age
• Preferably be fasting for 12 hours (minimum 8 hours) prior to enrollment
• Patients must be informed of the investigational nature of this study and sign and give written informed consent in accordance with institutional and federal guidelines.

Exclusion Criteria:

• None listed in protocol