Bioimpedance and Arterial Distension (SenseC1)
Bioimpedance of Human Tissue of the Upper Arm and Arterial Distension
調査の概要
状態
条件
詳細な説明
It is emphasized that measurements of pulse wave velocity was not a part of this trial, which implies that only uncalibrated blood pressures could be measured. The specific objectives were:
- To determine conductivities and permittivities in the spectral region from 1 KHz to 1 MHz for persons with: (a) a normal distribution of fat and muscles, (b) exceptionally thick layers of subcutaneous fat, and (c) exceptionally thin layers of subcutaneous fat. Both sexes should be represented.
- To verify that temporal variations synchronous with the heartbeat could be measured on all three groups.
Hypotheses:
A. That experimentally in vivo determined electrical parameters for tissues would differ considerably from theoretical values and from values measured in vitro experiments.
B. That the variations of the electrical parameters would exhibit little variation from person to person.
C. Those simple experimental relations can be established for the electrical parameters by including a simple vascularization model.
D. That it is possible to measure temporal variation of the impedance, which are synchronous with the heartbeat.
E. That the measured values would facilitate the calculation of the differential blood pressure with accuracies better than 10 mmHg.
研究の種類
入学 (実際)
連絡先と場所
研究場所
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Copenhagen、デンマーク、DK-4011
- Rigshopsitalet (Copenhagen Univ. Hospital)
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参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Age 18 - 80 years
- Mental ability to understand information to test subjects
Exclusion Criteria:
- Serious illness
- Allergic reactions to ECG or EMG electrodes
- Mentally unstable or unable to perceive instructions
- Metal implants
- Claustrophobia
- Disqualified for MR scanning
- Pregnant
研究計画
研究はどのように設計されていますか?
デザインの詳細
コホートと介入
グループ/コホート |
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Bioimpedance
8 females and 8 males BMI from 19 to 46 SBP from 119 to 182
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Conductivities and permittivities in the spectral region from 1 KHz to 1 MHz.
時間枠:1 hour
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Measured on persons with: (a) a normal distribution of fat and muscles, (b) exceptionally thick layers of subcutaneous fat, and (c) exceptionally thin layers of subcutaneous fat.
Both sexes should be represented.
Muscles and vessels followed expectations based on litterature values for electrical properties.
Subcutaneous fat had a higher conductivity and permittivity than predicted from literature values in all cases.
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1 hour
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Temporal variations synchronous with the heartbeat
時間枠:1 hour
|
The temporal variations of impedances measured on persons with: (a) a normal distribution of fat and muscles, (b) exceptionally thick layers of subcutaneous fat, and (c) exceptionally thin layers of subcutaneous fat.
Both sexes should be represented.
Temporal variations could be measured on all three groups.
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1 hour
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協力者と研究者
スポンサー
捜査官
- スタディディレクター:Lars Lading, Prof.、Sense A/S
- 主任研究者:Tine W Hansen, MD, PhD、Rigshospitalet (Copenhagen Univ. Hospital)
研究記録日
主要日程の研究
研究開始
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (見積もり)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
追加の関連 MeSH 用語
その他の研究ID番号
- H-1-2011-076
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