The Influence of Preoperative Cardiopulmonary Capacity on the Perioperative Lactate Level
The Influence of Preoperative Cardiopulmonary Capacity Mesured in MET's (Metabolic Equivalents) on the Perioperative Lactate Level
調査の概要
状態
詳細な説明
The determination of the cardiopulmonary (c/p) capacity is very important for the evaluation of every patient undergoing surgery. The ability to climb at least two flight of stairs is seen to be an acceptable c/p capacity for surgery. There are several ways to evaluate the fitness of patients. A common method to estimate the cardiopulmonary capacity is defining patients through the MET's (metabolic equivalents) scale. MET's can be defined relatively easy through a simple questionnaire. Patients with a reduced c/p capacity have less than 4 MET's, patients with a relatively good c/p capacity have 4-10 MET's and patients with a excellent c/p capacity have more than 10 MET's.
The lactate level in blood serum is a common parameter to asses anaerobic metabolism in patients. A high lactate level correlates with higher mortality rates and outcome.
To yet it is not clear if there exists a correlation between the preoperative cardiopulmonary capacity measured in MET's and the perioperative lactate level. We hypothysed that patients with a reduced cardiopulmonary capacity are associated with higher perioperative lactate levels, as these group of patients compensate the stressors operation/anesthesia less than patients with a good c/p capacity.
研究の種類
入学 (実際)
連絡先と場所
研究場所
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NRW
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Wuppertal、NRW、ドイツ、42283
- Helios Klinikum Wuppertal
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参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
サンプリング方法
調査対象母集団
説明
Inclusion Criteria:
- Age > 18 years
Exclusion Criteria:
- Cardiac surgery
研究計画
研究はどのように設計されていますか?
デザインの詳細
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
lactate - venous blood gas analysis
時間枠:venous lactate will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
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mmol/l
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venous lactate will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
icu in hospital mortality
時間枠:icu patients will be followed over their hospital stay over a maximum period of 6 months
|
icu patients will be followed over their hospital stay over a maximum period of 6 months
|
|
|
hemoglobin - venous blood gas analysis
時間枠:hemoglobin will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
|
g/dl
|
hemoglobin will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
|
|
icu ventilation time
時間枠:icu patients will be followed over their hospital stay over a maximum period of 6 months
|
hours/days
|
icu patients will be followed over their hospital stay over a maximum period of 6 months
|
協力者と研究者
捜査官
- スタディチェア:Gerhard Schneider, Prof.、Dept. Anaesthesiology
研究記録日
主要日程の研究
研究開始
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (見積もり)
学習記録の更新
投稿された最後の更新 (見積もり)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。