The Influence of Preoperative Cardiopulmonary Capacity on the Perioperative Lactate Level
The Influence of Preoperative Cardiopulmonary Capacity Mesured in MET's (Metabolic Equivalents) on the Perioperative Lactate Level
研究概览
详细说明
The determination of the cardiopulmonary (c/p) capacity is very important for the evaluation of every patient undergoing surgery. The ability to climb at least two flight of stairs is seen to be an acceptable c/p capacity for surgery. There are several ways to evaluate the fitness of patients. A common method to estimate the cardiopulmonary capacity is defining patients through the MET's (metabolic equivalents) scale. MET's can be defined relatively easy through a simple questionnaire. Patients with a reduced c/p capacity have less than 4 MET's, patients with a relatively good c/p capacity have 4-10 MET's and patients with a excellent c/p capacity have more than 10 MET's.
The lactate level in blood serum is a common parameter to asses anaerobic metabolism in patients. A high lactate level correlates with higher mortality rates and outcome.
To yet it is not clear if there exists a correlation between the preoperative cardiopulmonary capacity measured in MET's and the perioperative lactate level. We hypothysed that patients with a reduced cardiopulmonary capacity are associated with higher perioperative lactate levels, as these group of patients compensate the stressors operation/anesthesia less than patients with a good c/p capacity.
研究类型
注册 (实际的)
联系人和位置
学习地点
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NRW
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Wuppertal、NRW、德国、42283
- Helios Klinikum Wuppertal
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Age > 18 years
Exclusion Criteria:
- Cardiac surgery
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
lactate - venous blood gas analysis
大体时间:venous lactate will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
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mmol/l
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venous lactate will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
icu in hospital mortality
大体时间:icu patients will be followed over their hospital stay over a maximum period of 6 months
|
icu patients will be followed over their hospital stay over a maximum period of 6 months
|
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hemoglobin - venous blood gas analysis
大体时间:hemoglobin will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
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g/dl
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hemoglobin will be measured at anaesthesia induction and anesthesia termination - the average time frame is 2 hours
|
icu ventilation time
大体时间:icu patients will be followed over their hospital stay over a maximum period of 6 months
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hours/days
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icu patients will be followed over their hospital stay over a maximum period of 6 months
|
合作者和调查者
调查人员
- 学习椅:Gerhard Schneider, Prof.、Dept. Anaesthesiology
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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