Effects of a Single Bout of Resistance Training Session on Hormonal Response in Pre-pubertal and Pubertal Boys
: Resistance training induces strength gains in both children and adolescents. Exercise training is linked to anabolic functions through the GH-IGF-I axis. This has been demonstrated in studies showing a higher activity of GH and IGF-I in fitter adolescents and adults. Exercise also stimulates pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) that suppress the GH-IGF-I axis. This has been observed in endurance-type training, while resistance training has received less attention.
Boys experience a significant physiological muscle-growth change during puberty that is associated with increases in boys androgen levels. How maturation affects the hormonal response to resistance training in boys is unclear. Therefore, the purpose of the study is to compare the acute effects of a single bout of resistance training on hormones and pro-inflammatory cytokines in pre-pubertal and pubertal boys.
調査の概要
詳細な説明
Preliminary measurements:
Preliminary testing will include anthropometric measurements of body mass, height, body fat percentage, and lean leg volume (LLV). The maturation stage will be determined according to the Tanner scale. There will also be an assessment of maximal strength testing to determine exercise intensity for each individual. Two familiarization sessions will be conducted for muscular strength before the muscular strength testing session.
Main trial A venous blood sample will be collected pre-exercise at resting condition. The trial will start with a standardized warm-up followed by a short (20-30 min), high-intensity whole-body resistance training session. Venous blood samples will be collected immediately after the completion of the training session and during the recovery period.
研究の種類
入学 (予想される)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前:Apostolos Theos, PhD
- 電話番号:+46702811565
- メール:apostolos.theos@umu.se
研究場所
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Västerbotten
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Umeå、Västerbotten、スウェーデン、901 87
- Umeå Movement and Exercise Laboratory, Umeå University
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コンタクト:
- Apostolos Theos, PhD
- 電話番号:+46702811565
- メール:apostolos.theos@umu.se
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コンタクト:
- Tobias Stenlund, PhD
- 電話番号:+46907868040
- メール:tobias.stenlund@umu.se
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参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- Healthy boys (n=40)
- Physically active, defined as a minimum of 2 years experience in a sports club
- Biological age range: 20 pre-pubertal (Tanner I-II) - 20 pubertal (Tanner III-IV) boys
- No previous experience of structured resistance training
Exclusion Criteria:
- Chronic diseases that affect full participation
- Injuries that limit full participation
研究計画
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:他の
- 割り当て:非ランダム化
- 介入モデル:並列代入
- マスキング:独身
武器と介入
参加者グループ / アーム |
介入・治療 |
---|---|
実験的:Resistance Training Session
Resistance training.
Heavy resistance training.
10 reps x 3 set of upper- and lower-body resistance exercises
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Both groups will perform a resistance training session consisted of 10 reps x 3 set of upper- and lower-body resistance exercises.
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介入なし:Control
Control activity.
None-exercising.
30 min of rest
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Growth Hormone Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood Concentration of Growth Hormone
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Growth Hormone Post exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood Concentration of Growth Hormone
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Right after the completion of the exercise intervention (Post values)
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Change from Baseline Growth Hormone 15 minutes post exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood Concentration of Growth Hormone
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15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Growth Hormone 30 minutes post exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood Concentration of Growth Hormone
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30 minutes after the completion of the exercise intervention (Post-30 values)
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Insulin-like Growth Factor-1 Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of Insulin-like Growth Factor-1
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Insulin-like Growth Factor-1 Post exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of Insulin-like Growth Factor-1
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Right after the completion of the exercise intervention (Post values)
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Change from Baseline Insulin-like Growth Factor-1 15 minutes Post exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of Insulin-like Growth Factor-1
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15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Insulin-like Growth Factor-1 30 minutes Post exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of Insulin-like Growth Factor-1
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30 minutes after the completion of the exercise intervention (Post-30 values)
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Cortisol Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of Cortisol
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Cortisol Post exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of Cortisol
|
Right after the completion of the exercise intervention (Post values)
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Change from Baseline Cortisol 15 minutes Post exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of Cortisol
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15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Cortisol 30 minutes Post exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of Cortisol
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30 minutes after the completion of the exercise intervention (Post-30 values)
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Testosterone Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of testosterone
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Testosterone Post Exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of testosterone
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Right after the completion of the exercise intervention (Post values)
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Change from Baseline Testosterone 15 minutes Post Exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of testosterone
|
15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Testosterone 30 minutes Post Exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of testosterone
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30 minutes after the completion of the exercise intervention (Post-30 values)
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Interleukin-6 Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of Interleukin-6
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Interleukin-6 Post Exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of Interleukin-6
|
Right after the completion of the exercise intervention (Post values)
|
Change from Baseline Interleukin-6 15 minutes Post Exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of Interleukin-6
|
15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Interleukin-6 30 minutes Post Exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of Interleukin-6
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30 minutes after the completion of the exercise intervention (Post-30 values)
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Interleukin-1 alpha Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of Interleukin-1 alpha
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Interleukin-1 alpha Post Exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of Interleukin-1 alpha
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Right after the completion of the exercise intervention (Post values)
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Change from Baseline Interleukin-1 alpha 15 minutes Post Exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of Interleukin-1 alpha
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15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Interleukin-1 alpha 30 minutes Post Exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of Interleukin-1 alpha
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30 minutes after the completion of the exercise intervention (Post-30 values)
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Tumor Necrosis Factor alpha Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of Tumor Necrosis Factor alpha
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Tumor Necrosis Factor alpha Post Exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of Tumor Necrosis Factor alpha
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Right after the completion of the exercise intervention (Post values)
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Change from Baseline Tumor Necrosis Factor alpha 15 minutes Post Exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of Tumor Necrosis Factor alpha
|
15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Tumor Necrosis Factor alpha 30 minutes Post Exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of Tumor Necrosis Factor alpha
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30 minutes after the completion of the exercise intervention (Post-30 values)
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Sex Hormone Binding Globulin Baseline
時間枠:Baseline testing before the exercise intervention (Pre values)
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Blood concentration of Sex Hormone Binding Globulin
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Baseline testing before the exercise intervention (Pre values)
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Change from Baseline Baseline Sex Hormone Binding Post Exercise
時間枠:Right after the completion of the exercise intervention (Post values)
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Blood concentration of Sex Hormone Binding Globulin
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Right after the completion of the exercise intervention (Post values)
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Change from Baseline Baseline Sex Hormone Binding 15 minutes Post Exercise
時間枠:15 minutes after the completion of the exercise intervention (Post-15 values)
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Blood concentration of Sex Hormone Binding Globulin
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15 minutes after the completion of the exercise intervention (Post-15 values)
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Change from Baseline Sex Hormone Binding Globulin 30 minutes Post Exercise
時間枠:30 minutes after the completion of the exercise intervention (Post-30 values)
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Blood concentration of Sex Hormone Binding Globulin
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30 minutes after the completion of the exercise intervention (Post-30 values)
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協力者と研究者
スポンサー
捜査官
- 主任研究者:Apostolos Theos, PhD、Umea University
研究記録日
主要日程の研究
研究開始 (予想される)
一次修了 (予想される)
研究の完了 (予想される)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
その他の研究ID番号
- 2020-03179
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Resistance Trainingの臨床試験
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University of MinnesotaNational Institute of Mental Health (NIMH)募集精神病性障害 | 統合失調症 | 統合失調症スペクトラムおよびその他の精神病性障害 | 統合失調感情障害 | 精神病 | 統合失調感情障害 | 統合失調症性障害 | 精神病、感情的 | 精神性気分障害 | 精神病患者番号/その他アメリカ
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VA Office of Research and Development募集
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University of WashingtonNational Institute on Aging (NIA); Kaiser Permanente完了
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Queens College, The City University of New York完了
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Universidade Metodista de Piracicaba完了アスレチックパフォーマンス | アスリート | 呼吸筋 | 呼吸法 | 有酸素容量
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Diakonhjemmet HospitalThe Dam Foundation; The Norwegian Council for Musculoskeletal Health募集