Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults
Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults, a Randomized Controlled Trial
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence brain function and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and beneficial changes to biomarkers with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
調査の概要
詳細な説明
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence multiple neurobiological pathways such as neurotrophic signaling, neurotransmitter regulation, oxidative balance, and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and modulated biomarkers related to the hypothalamic-pituitary-adrenal axis with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
研究の種類
入学 (推定)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前：Carol Johnston
- 電話番号：6024963463
- メール：carol.johnston@asu.edu
研究場所
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Arizona
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Phoenix、Arizona、アメリカ、85004
- 募集
- Health North ASU Downtown Campus
-
コンタクト：
- Carol Johnston, PhD
- 電話番号：6024962539
- メール：carol.johnston@asu.edu
-
-
参加基準
適格基準
就学可能な年齢
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- Healthy young adults
- 18-30 years of age
Exclusion Criteria:
- medication/drug use that has not been consistent for the previous 3 months or will be discontinued during the trial
- unresolved chronic medical conditions (e.g., presence of persistent symptomology)
- diagnosed clinical depression
- acute illness
- regular use of cigarettes or marijuana
- pregnant or lactating women
- not fluent in English
- currently competing in sports or unusually high-intensity exercise protocols (e.g., high-intensity exercise greater than 30 minutes most days of the week)
- current use of ginseng or adaptogenic supplements, or allergy to ginseng
- any significant food allergies
- not willing to attend two in-person lab visits in downtown Phoenix and follow study protocol (including abstaining from caffeine in the 12 hours prior to testing)
研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：基礎科学
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：ダブル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：ginseng
ginseng |
This study will test the efficacy of ginseng on health compared to placebo treatment. |
|
プラセボコンパレーター：Placebo
strawberry gummy (2) |
This study will test the efficacy of ginseng on health compared to placebo treatment. |
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
cognitive performance
時間枠：2 hours post ingestion
|
Trail Making Test: measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds) |
2 hours post ingestion
|
|
cognitive performance
時間枠：2 weeks
|
Trail Making Test measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds) |
2 weeks
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
stress
時間枠：2 weeks
|
Perceived Stress Scale: higher scores indicate higher stress |
2 weeks
|
|
mental well being
時間枠：2 weeks
|
Warwick-Edinburgh Mental Well-Being Scale: higher scores indicating greater positive mental wellbeing |
2 weeks
|
その他の成果指標
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
cognitive performance
時間枠：2 hours post ingestion
|
Stroop test: measures attention span, reaction time, and ability to resist distractions |
2 hours post ingestion
|
|
cognitive performance
時間枠：2 hours post ingestion
|
reaction time test: measured by the elapsed time between stimulus onset and an individual's response |
2 hours post ingestion
|
協力者と研究者
スポンサー
捜査官
- 主任研究者：Carol Johnston、Arizona State University
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
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