Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults
Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults, a Randomized Controlled Trial
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence brain function and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and beneficial changes to biomarkers with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
研究概览
详细说明
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence multiple neurobiological pathways such as neurotrophic signaling, neurotransmitter regulation, oxidative balance, and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and modulated biomarkers related to the hypothalamic-pituitary-adrenal axis with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名:Carol Johnston
- 电话号码:6024963463
- 邮箱:carol.johnston@asu.edu
学习地点
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Arizona
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Phoenix、Arizona、美国、85004
- 招聘中
- Health North ASU Downtown Campus
-
接触:
- Carol Johnston, PhD
- 电话号码:6024962539
- 邮箱:carol.johnston@asu.edu
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Healthy young adults
- 18-30 years of age
Exclusion Criteria:
- medication/drug use that has not been consistent for the previous 3 months or will be discontinued during the trial
- unresolved chronic medical conditions (e.g., presence of persistent symptomology)
- diagnosed clinical depression
- acute illness
- regular use of cigarettes or marijuana
- pregnant or lactating women
- not fluent in English
- currently competing in sports or unusually high-intensity exercise protocols (e.g., high-intensity exercise greater than 30 minutes most days of the week)
- current use of ginseng or adaptogenic supplements, or allergy to ginseng
- any significant food allergies
- not willing to attend two in-person lab visits in downtown Phoenix and follow study protocol (including abstaining from caffeine in the 12 hours prior to testing)
学习计划
研究是如何设计的?
设计细节
- 主要用途:基础科学
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的:ginseng
ginseng |
This study will test the efficacy of ginseng on health compared to placebo treatment. |
|
安慰剂比较:Placebo
strawberry gummy (2) |
This study will test the efficacy of ginseng on health compared to placebo treatment. |
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
cognitive performance
大体时间:2 hours post ingestion
|
Trail Making Test: measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds) |
2 hours post ingestion
|
|
cognitive performance
大体时间:2 weeks
|
Trail Making Test measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds) |
2 weeks
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
stress
大体时间:2 weeks
|
Perceived Stress Scale: higher scores indicate higher stress |
2 weeks
|
|
mental well being
大体时间:2 weeks
|
Warwick-Edinburgh Mental Well-Being Scale: higher scores indicating greater positive mental wellbeing |
2 weeks
|
其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
cognitive performance
大体时间:2 hours post ingestion
|
Stroop test: measures attention span, reaction time, and ability to resist distractions |
2 hours post ingestion
|
|
cognitive performance
大体时间:2 hours post ingestion
|
reaction time test: measured by the elapsed time between stimulus onset and an individual's response |
2 hours post ingestion
|
合作者和调查者
调查人员
- 首席研究员:Carol Johnston、Arizona State University
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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