Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults
Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults, a Randomized Controlled Trial
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence brain function and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and beneficial changes to biomarkers with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
연구 개요
상세 설명
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being. Neurological functions such as working memory, attention regulation, executive control, and emotional processing are highly sensitive to stressors, leaving young adults vulnerable to daily fluctuations in cognitive efficiency. Recent findings from the Healthy Minds Network (2025) indicate that although rates of moderate to severe depression among college students declined from 44% in 2022 to 37% in 2025, and anxiety symptoms fell from 37% to 32%, levels of psychological flourishing also dropped, falling to 36% despite these improvements.
Ginseng contains bioactive compounds known as ginsenosides that favorably influence multiple neurobiological pathways such as neurotrophic signaling, neurotransmitter regulation, oxidative balance, and inflammatory cascades. Studies in stressed and moderately stressed adults demonstrated reduced perceived stress, improved emotional processing, enhanced cognitive performance, and modulated biomarkers related to the hypothalamic-pituitary-adrenal axis with ginseng supplementation. In addition, randomized controlled trials reported improvements in mood regulation, fatigue resistance, and aspects of working memory and attention following short-term ginseng supplementation. This study will examine the effects of daily red panax ginseng supplementation (3000 mg/day; two 1500 mg Red Panax gummies) on cognitive performance and emotional well-being in healthy young adults.
연구 유형
등록 (추정된)
단계
- 해당 없음
연락처 및 위치
연구 연락처
- 이름: Carol Johnston
- 전화번호: 6024963463
- 이메일: carol.johnston@asu.edu
참여기준
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
- Healthy young adults
- 18-30 years of age
Exclusion Criteria:
- medication/drug use that has not been consistent for the previous 3 months or will be discontinued during the trial
- unresolved chronic medical conditions (e.g., presence of persistent symptomology)
- diagnosed clinical depression
- acute illness
- regular use of cigarettes or marijuana
- pregnant or lactating women
- not fluent in English
- currently competing in sports or unusually high-intensity exercise protocols (e.g., high-intensity exercise greater than 30 minutes most days of the week)
- current use of ginseng or adaptogenic supplements, or allergy to ginseng
- any significant food allergies
- not willing to attend two in-person lab visits in downtown Phoenix and follow study protocol (including abstaining from caffeine in the 12 hours prior to testing)
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 기초 과학
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 더블
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
|
실험적: ginseng
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This study will test the efficacy of ginseng on health compared to placebo treatment.
|
|
위약 비교기: Placebo
strawberry gummy (2)
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This study will test the efficacy of ginseng on health compared to placebo treatment.
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
cognitive performance
기간: 2 hours post ingestion
|
Trail Making Test: measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds)
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2 hours post ingestion
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cognitive performance
기간: 2 weeks
|
Trail Making Test measures cognitive flexibility; visual attention, and executive function, with interpretation based on completion times (in seconds)
|
2 weeks
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
stress
기간: 2 weeks
|
Perceived Stress Scale: higher scores indicate higher stress
|
2 weeks
|
|
mental well being
기간: 2 weeks
|
Warwick-Edinburgh Mental Well-Being Scale: higher scores indicating greater positive mental wellbeing
|
2 weeks
|
기타 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
cognitive performance
기간: 2 hours post ingestion
|
Stroop test: measures attention span, reaction time, and ability to resist distractions
|
2 hours post ingestion
|
|
cognitive performance
기간: 2 hours post ingestion
|
reaction time test: measured by the elapsed time between stimulus onset and an individual's response
|
2 hours post ingestion
|
공동 작업자 및 조사자
수사관
- 수석 연구원: Carol Johnston, Arizona State University
연구 기록 날짜
연구 주요 날짜
연구 시작 (추정된)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
Ginseng에 대한 임상 시험
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Unity Health TorontoHeart and Stroke Foundation of Canada완전한
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LongStar HealthPro, Inc. DBA Farlong PharmaceuticalKGK Science Inc.; Yunnan PanLongYunHai Pharmaceuticals, Ltd.완전한
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Daegu Catholic University Medical CenterThe Korean Society of Ginseng완전한
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Guang'anmen Hospital of China Academy of Chinese...Affiliated Hospital of Hebei University; Second Affiliated Hospital of Nanchang University 그리고 다른 협력자들모병