Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women
The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:
Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?
The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:
Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.
Participants will:
Attend three experimental sessions in random order separated by at least 7 days.
Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.
Undergo height, weight, and body mass index measurements.
調査の概要
状態
研究の種類
入学 (推定)
段階
- 適用できない
連絡先と場所
研究連絡先
- 名前：Bushra k Alharbi
- 電話番号：+966556913301
- メール：bu1.kh2@gmail.com
研究場所
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Riyadh、サウジアラビア
- 募集
- King Saud University
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参加基準
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
説明
Inclusion Criteria:
Female participants aged 18-45 years. Healthy individuals with normal blood pressure levels (systolic blood pressure <130 mmHg and diastolic blood pressure <80 mmHg).
Body mass index (BMI) less than 30 kg/m². Ability to stand without support. No history of cardiovascular disease or chronic diseases that may affect study outcomes.
Exclusion Criteria:
Pregnancy or breastfeeding. Back injuries preventing prolonged sitting. Use of medications that may affect cardiovascular responses, including antihypertensive, antidiabetic, antidepressant, or hormonal medications.
Presence of chronic diseases or cardiovascular conditions affecting vascular health.
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研究計画
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：基礎科学
- 割り当て：ランダム化
- 介入モデル：クロスオーバー割り当て
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的：Short Standing Interval
Participants will complete 3 hours of sitting interrupted with 10 minutes of standing every hour.
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Participants will interrupt prolonged sitting with 10 minutes of standing every hour during 3 hours of sitting.
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実験的：Continuous Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 continuous minutes of standing every hour.
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Participants will interrupt prolonged sitting with 30 continuous minutes of standing every hour during 3 hours of sitting.
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実験的：Intermittent Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 minutes of standing every hour divided into three 10-minute standing bouts.
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Participants will interrupt prolonged sitting with 30 minutes of standing every hour divided into three 10-minute standing bouts during 3 hours of sitting.
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Blood Pressure
時間枠：Baseline, 1 hour, 2 hours, and 3 hours
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Systolic and diastolic blood pressure will be measured before sitting and after each hour during the experimental sessions.
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Baseline, 1 hour, 2 hours, and 3 hours
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Pulse Wave Velocity
時間枠：Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Heart Rate
時間枠：Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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協力者と研究者
スポンサー
捜査官
- スタディチェア：Abdullah B Alansare, PhD、King Saud University
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (推定)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
この情報は、Web サイト clinicaltrials.gov から変更なしで直接取得したものです。研究の詳細を変更、削除、または更新するリクエストがある場合は、register@clinicaltrials.gov。 までご連絡ください。 clinicaltrials.gov に変更が加えられるとすぐに、ウェブサイトでも自動的に更新されます。