Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women
The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:
Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?
The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:
Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.
Participants will:
Attend three experimental sessions in random order separated by at least 7 days.
Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.
Undergo height, weight, and body mass index measurements.
Descripción general del estudio
Estado
Tipo de estudio
Inscripción (Estimado)
Fase
- No aplica
Contactos y Ubicaciones
Estudio Contacto
- Nombre: Bushra k Alharbi
- Número de teléfono: +966556913301
- Correo electrónico: bu1.kh2@gmail.com
Ubicaciones de estudio
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Riyadh, Arabia Saudita
- Reclutamiento
- King Saud University
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Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
Acepta Voluntarios Saludables
Descripción
Inclusion Criteria:
Female participants aged 18-45 years. Healthy individuals with normal blood pressure levels (systolic blood pressure <130 mmHg and diastolic blood pressure <80 mmHg).
Body mass index (BMI) less than 30 kg/m². Ability to stand without support. No history of cardiovascular disease or chronic diseases that may affect study outcomes.
Exclusion Criteria:
Pregnancy or breastfeeding. Back injuries preventing prolonged sitting. Use of medications that may affect cardiovascular responses, including antihypertensive, antidiabetic, antidepressant, or hormonal medications.
Presence of chronic diseases or cardiovascular conditions affecting vascular health.
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Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Ciencia básica
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación cruzada
- Enmascaramiento: Ninguno (etiqueta abierta)
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
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Experimental: Short Standing Interval
Participants will complete 3 hours of sitting interrupted with 10 minutes of standing every hour.
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Participants will interrupt prolonged sitting with 10 minutes of standing every hour during 3 hours of sitting.
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Experimental: Continuous Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 continuous minutes of standing every hour.
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Participants will interrupt prolonged sitting with 30 continuous minutes of standing every hour during 3 hours of sitting.
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Experimental: Intermittent Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 minutes of standing every hour divided into three 10-minute standing bouts.
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Participants will interrupt prolonged sitting with 30 minutes of standing every hour divided into three 10-minute standing bouts during 3 hours of sitting.
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
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Blood Pressure
Periodo de tiempo: Baseline, 1 hour, 2 hours, and 3 hours
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Systolic and diastolic blood pressure will be measured before sitting and after each hour during the experimental sessions.
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Baseline, 1 hour, 2 hours, and 3 hours
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Pulse Wave Velocity
Periodo de tiempo: Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Heart Rate
Periodo de tiempo: Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Colaboradores e Investigadores
Patrocinador
Investigadores
- Silla de estudio: Abdullah B Alansare, PhD, King Saud University
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Estimado)
Finalización del estudio (Estimado)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- E-25-10479
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
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