Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women
The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:
Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?
The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:
Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.
Participants will:
Attend three experimental sessions in random order separated by at least 7 days.
Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.
Undergo height, weight, and body mass index measurements.
Studieoversigt
Status
Undersøgelsestype
Tilmelding (Anslået)
Fase
- Ikke anvendelig
Kontakter og lokationer
Studiekontakt
- Navn: Bushra k Alharbi
- Telefonnummer: +966556913301
- E-mail: bu1.kh2@gmail.com
Studiesteder
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Riyadh, Saudi Arabien
- Rekruttering
- King Saud University
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
- Voksen
Tager imod sunde frivillige
Beskrivelse
Inclusion Criteria:
Female participants aged 18-45 years. Healthy individuals with normal blood pressure levels (systolic blood pressure <130 mmHg and diastolic blood pressure <80 mmHg).
Body mass index (BMI) less than 30 kg/m². Ability to stand without support. No history of cardiovascular disease or chronic diseases that may affect study outcomes.
Exclusion Criteria:
Pregnancy or breastfeeding. Back injuries preventing prolonged sitting. Use of medications that may affect cardiovascular responses, including antihypertensive, antidiabetic, antidepressant, or hormonal medications.
Presence of chronic diseases or cardiovascular conditions affecting vascular health.
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Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Grundvidenskab
- Tildeling: Randomiseret
- Interventionel model: Crossover opgave
- Maskning: Ingen (Åben etiket)
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
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Eksperimentel: Short Standing Interval
Participants will complete 3 hours of sitting interrupted with 10 minutes of standing every hour.
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Participants will interrupt prolonged sitting with 10 minutes of standing every hour during 3 hours of sitting.
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Eksperimentel: Continuous Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 continuous minutes of standing every hour.
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Participants will interrupt prolonged sitting with 30 continuous minutes of standing every hour during 3 hours of sitting.
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Eksperimentel: Intermittent Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 minutes of standing every hour divided into three 10-minute standing bouts.
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Participants will interrupt prolonged sitting with 30 minutes of standing every hour divided into three 10-minute standing bouts during 3 hours of sitting.
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Blood Pressure
Tidsramme: Baseline, 1 hour, 2 hours, and 3 hours
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Systolic and diastolic blood pressure will be measured before sitting and after each hour during the experimental sessions.
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Baseline, 1 hour, 2 hours, and 3 hours
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Pulse Wave Velocity
Tidsramme: Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Heart Rate
Tidsramme: Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Samarbejdspartnere og efterforskere
Sponsor
Efterforskere
- Studiestol: Abdullah B Alansare, PhD, King Saud University
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Anslået)
Studieafslutning (Anslået)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Faktiske)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- E-25-10479
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
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