Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women
The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:
Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?
The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:
Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.
Participants will:
Attend three experimental sessions in random order separated by at least 7 days.
Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.
Undergo height, weight, and body mass index measurements.
Studieöversikt
Status
Betingelser
Intervention / Behandling
Studietyp
Inskrivning (Beräknad)
Fas
- Inte tillämpbar
Kontakter och platser
Studiekontakt
- Namn: Bushra k Alharbi
- Telefonnummer: +966556913301
- E-post: bu1.kh2@gmail.com
Studieorter
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Riyadh, Saudiarabien
- Rekrytering
- King Saud University
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Deltagandekriterier
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
Tar emot friska volontärer
Beskrivning
Inclusion Criteria:
Female participants aged 18-45 years. Healthy individuals with normal blood pressure levels (systolic blood pressure <130 mmHg and diastolic blood pressure <80 mmHg).
Body mass index (BMI) less than 30 kg/m². Ability to stand without support. No history of cardiovascular disease or chronic diseases that may affect study outcomes.
Exclusion Criteria:
Pregnancy or breastfeeding. Back injuries preventing prolonged sitting. Use of medications that may affect cardiovascular responses, including antihypertensive, antidiabetic, antidepressant, or hormonal medications.
Presence of chronic diseases or cardiovascular conditions affecting vascular health.
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Studieplan
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Grundläggande vetenskap
- Tilldelning: Randomiserad
- Interventionsmodell: Crossover tilldelning
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
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Experimentell: Short Standing Interval
Participants will complete 3 hours of sitting interrupted with 10 minutes of standing every hour.
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Participants will interrupt prolonged sitting with 10 minutes of standing every hour during 3 hours of sitting.
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Experimentell: Continuous Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 continuous minutes of standing every hour.
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Participants will interrupt prolonged sitting with 30 continuous minutes of standing every hour during 3 hours of sitting.
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Experimentell: Intermittent Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 minutes of standing every hour divided into three 10-minute standing bouts.
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Participants will interrupt prolonged sitting with 30 minutes of standing every hour divided into three 10-minute standing bouts during 3 hours of sitting.
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Blood Pressure
Tidsram: Baseline, 1 hour, 2 hours, and 3 hours
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Systolic and diastolic blood pressure will be measured before sitting and after each hour during the experimental sessions.
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Baseline, 1 hour, 2 hours, and 3 hours
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Pulse Wave Velocity
Tidsram: Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Heart Rate
Tidsram: Baseline, 1 hour, 2 hours, and 3 hours
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Baseline, 1 hour, 2 hours, and 3 hours
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Samarbetspartners och utredare
Sponsor
Utredare
- Studiestol: Abdullah B Alansare, PhD, King Saud University
Studieavstämningsdatum
Studera stora datum
Studiestart (Faktisk)
Primärt slutförande (Beräknad)
Avslutad studie (Beräknad)
Studieregistreringsdatum
Först inskickad
Först inskickad som uppfyllde QC-kriterierna
Första postat (Faktisk)
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
Senast verifierad
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- E-25-10479
Plan för individuella deltagardata (IPD)
Planerar du att dela individuella deltagardata (IPD)?
Läkemedels- och apparatinformation, studiedokument
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