The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors (BPS2)
연구 개요
상세 설명
Fifteen (n=15) sedentary adult overweight males will be included in the study. All participants will undergo the four interventions in a randomized cross-over design. Wash out between intervention will be minimum four days.
Control (CON): Participants will be sedentary. Sedentary time will be spent sitting in a chair, restricted to sedentary behaviors (working on a computer, reading, watching TV, etc.), with a target MET below 1.5 (i.e. 1.5 times REE). Participants will only be allowed to stand or walk to go to the toilet.
Breaker: Participants will be breaking up prolonged sitting with 2 min intervals of low intensity walking.
Intermediate: Participants will be breaking up prolonged sitting with 6 min intervals of low intensity walking
Prolonger: Participants will be breaking up prolonged sitting with 12 min intervals of low intensity walking
All interventions will be matched for total physical activity as well as sitting. Thus, we aim for the active interventions to be iso-caloric.
연구 유형
등록 (실제)
단계
- 해당 없음
연락처 및 위치
연구 장소
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Copenhagen, 덴마크, 2100
- Center for Physical Activity Research, Copenhagen University Hospital
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
- Males, age 20-50 years, waist-to-height ratio ≥ 0.5 and/or waist circumference ≥ 102 cm.
Exclusion Criteria:
- Clinically diagnosed diabetes, uncontrolled hypertension, use of glucose- and/or lipid-lowering medication, smoking, evidence of thyroid, liver, lung, heart or kidney disease, non-sedentary occupation, and VO2max levels above the considered average fitness according to age (Shvartz & Reibold 1990), contraindications to increased levels of physical activity.
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 방지
- 할당: 무작위
- 중재 모델: 크로스오버 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: Control
Participants will spend 8 hours sedentary.
Sedentary time will be spent sitting in a chair, restricted to sedentary behaviors (working on a computer, reading, watching TV, etc.) Participants will only be allowed to stand or walk to go to the toilet.
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Control intervention
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실험적: Breaker
Participants will spend a total of 7 hours and 12 min sedentary and a total of 48 min breaking sitting time with LPA.
Sedentary time will be done in bouts of 18 min with 2 min of light walking.
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Short breaks of physical activity
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실험적: Intermediate
Total duration of sedentary time and LPA time will be the same as in Breaker.
Sedentary time will be done in bouts of 54 min with 6 min of LPA between each bout.
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Intermediate breaks of physical activity
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실험적: Prolonger
Total duration of sedentary time and LPA time will be the same as in Breaker.
Sedentary time will be done in bouts of 108 min with 12 min of LPA between each bout.
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longer breaks of physical activity
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
기간 |
|---|---|
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AUC post prandial glucose concentration
기간: 6 hours
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6 hours
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2차 결과 측정
결과 측정 |
기간 |
|---|---|
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AUC post prandial insulin concentration
기간: 6 hours
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6 hours
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AUC post prandial c-peptide concentration
기간: 6 hours
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6 hours
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AUC post prandial triglyceride concentration
기간: 6 hours
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6 hours
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AUC post prandial total cholesterol concentration
기간: 6 hours
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6 hours
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AUC post prandial ldl concentration
기간: 6 hours
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6 hours
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AUC post prandial hdl concentration
기간: 6 hours
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6 hours
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AUC post prandial glucagon concentration
기간: 6 hours
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6 hours
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Mean 24 hour glucose concentration
기간: 24 hours
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24 hours
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Variation in 24 hour glucose concentration
기간: 24 hours
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24 hours
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Maximum in 24 hour glucose concentration
기간: 24 hours
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24 hours
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공동 작업자 및 조사자
수사관
- 수석 연구원: Mathias Ried, PhD, Group Leader
연구 기록 날짜
연구 주요 날짜
연구 시작
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (추정)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
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