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Comparison of Gastric Volume After 6-hour and 8-hour Fasting in Patient Scheduled for Elective Surgery

2021년 5월 5일 업데이트: Raden Besthadi Sukmono, Indonesia University

Preoperative fasting was a common practice to decrease perioperative aspiration risk. Duration of fasting was proportional to gastric volume. Short fasting duration may increase aspiration risk. However, prolonged perioperative fasting duration may lead to dehydration and hypoglycemia.

The objective of this study was to analyze gastric volume after 6-hour and 8-hour duration of fasting after consumption of solid meal on patients scheduled for elective surgery.

This was a cohort study recruiting 37 subjects from January to February 2019. Subjects were patients scheduled for elective non-digestive surgery in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Before fasting, all subjects consumed standard Cipto Mangunkusumo meal and was later assessed for gastric volume using ultrasound at 6 and 8 hour after meal was consumed.

연구 개요

상태

완전한

상세 설명

Background. Preoperative fasting was a common practice to decrease perioperative aspiration risk. Duration of fasting was proportional to gastric volume. Short fasting duration may increase aspiration risk. However, prolonged perioperative fasting duration may lead to dehydration and hypoglycemia. The protocols of 8 hours preoperative fasting was recommended by American Society of Anesthesiologist (ASA) after a full meal. The meal recognized by ASA to make this guidelines were Western diet that contains more fat. South East Asian (SEA) standard solid meal mainly contains rice and less protein and fats. We hypothesized 6-hours compared with 8-hours fasting was sufficient to provide ideal gastric volume for preoperative fasting after SEA standard solid meal. The objective of this study was to analyze gastric volume after 6-hour and 8-hour of fasting after consumption of SEA standard solid meal on patients scheduled for elective surgery.

Methods This was a cohort study recruiting 37 subjects from January to February 2019. Subjects were patients scheduled for elective non-digestive surgery in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Inclusion criteria were age between 18 to 60 years old, have no nutritional status disorder, and ASA physical status of 1 or 2. The exclusion criteria were patients with diabetes mellitus, pregnancy, abdominal distention, history of dyspepsia, and intestinal motility disturbances.

Subjects agreed to take part in the research, will be initial examined for obtaining demographic data: age, weight and height, type of surgery to be performed, and preoperative examinations. The subject will start 8 hours of fasting before the surgical planning time. Before fasting, the subjects were given Cipto Mangunkusumo Hospital food standardized nutritional levels. Subjects were given 1 hour to consume the food. Six hours after the standard meal is consumed, an ultrasound examination will be performed in the right lateral decubitus position to obtain ultrasound imaging of the antrum. After that, the subject continued fasting until 8 hours after meal and ultrasound examination was performed using the same technique to obtain images of ultrasound imaging of the antrum. Imaging pictures are taken at the time relaxation of the antrum, between two contractions. The results of this imaging are stored and assessments of antrum craniocaudal (CC) and anteroposterior (AP) diameters were performed by research assistants who don't know when the image was taken. These measurements were used to calculate Cross Sectional Area (CSA) using the formula of CSA=(π×CC×AP)/4. The Gastric Volume (GV) was then calculated with the formula GV=27.0+(14.6×CSA)-(1.28×age).

The primary data obtained was the result of repeated examinations. The analysis was adjusted using the Bonferonni correction factor. Categorical data was analyzed using the McNemar test. The results of data processing are displayed in tabular form. The gastric volume was grouped into sufficient and insufficient with a border value of 1.5ml/kg.

연구 유형

관찰

등록 (실제)

37

연락처 및 위치

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연구 장소

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

18년 (성인)

건강한 자원 봉사자를 받아들입니다

아니

연구 대상 성별

모두

샘플링 방법

비확률 샘플

연구 인구

This was a cohort study for 37 subjects from January to February 2019. Subjects were patients scheduled for elective non-digestive surgery in Cipto Mangunkusumo Hospital

설명

Inclusion Criteria:

  • The inclusion criteria were patients aged 18-60 years
  • ASA 1-2 who would undergo non-digestive elective surgery in Cipto Mangunkusumo Hospital
  • Body mass index between 20-30 kg/m2

Exclusion Criteria:

  • patient who is not willing to enter the study
  • patients with diabetes mellitus
  • pregnancy
  • abdominal distension
  • intestinal motility disorders
  • history of dyspepsia
  • patients who do not receive the standard Cipto Mangunkusumo Hospital diet
  • changes of the surgery schedule in which the patient is unable to do 8-hours fasting before surgery
  • the patient who has an emergency in the perioperative period
  • the patient was unable to consume the standard food provided

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

코호트 및 개입

그룹/코호트
개입 / 치료
6-hours fasting gastric volume
gastric volume measured after 6-hours fasting
6-hours and 8-hours fasting before elective surgery
8-hours fasting gastric volume
gastric volume measured after 8-hours fasting
6-hours and 8-hours fasting before elective surgery

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
Gastric Volume 6-hours
기간: After 6-hours of preoperative fasting
Gastric volume measured with ultrasound after 6-hours of preoperative fasting
After 6-hours of preoperative fasting
Gastric Volume 8-hours
기간: After 8-hours of preoperative fasting
Gastric volume measured with ultrasound after 8-hours of preoperative fasting
After 8-hours of preoperative fasting

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여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (실제)

2019년 1월 1일

기본 완료 (실제)

2019년 2월 28일

연구 완료 (실제)

2019년 4월 30일

연구 등록 날짜

최초 제출

2021년 4월 21일

QC 기준을 충족하는 최초 제출

2021년 5월 2일

처음 게시됨 (실제)

2021년 5월 6일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2021년 5월 10일

QC 기준을 충족하는 마지막 업데이트 제출

2021년 5월 5일

마지막으로 확인됨

2021년 5월 1일

추가 정보

이 연구와 관련된 용어

기타 연구 ID 번호

  • GVES

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아니요

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Fasting for elective surgery에 대한 임상 시험

3
구독하다