The Combined Multicomponent Intervention Specifically in Rural Community Older Adults at High Risk for Mild Cognition Impairment (CMintervention)
2026년 5월 13일 업데이트: Xiaoying Wang
Elderly Disability (Dementia) Prevention and Intervention Project in Jinjiang Community, China
This project aims to test whether a combined multicomponent (CM) program - including health education, cognitive training, and traditional Chinese exercises - is feasible and effective for rural older adults who are at high risk of mild cognitive impairment (MCI).
The program is designed to help maintain or improve cognitive function and overall well-being.
연구 개요
상세 설명
Health education sessions: One 30-minute lecture every 4 weeks, covering topics such as diet, sleep, chronic disease management, and brain health.
Cognitive training: Weekly 45-minute sessions using fun mini-games to train memory, attention, arithmetic, and logical thinking.
Physical exercise: Weekly 45-minute sessions of traditional Chinese exercises (Baduanjin and Shiqiaoshou) to improve balance, flexibility, and fitness.
연구 유형
중재적
등록 (실제)
235
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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Fujian
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Quanzhou, Fujian, 중국
- Yuxi, Gucuo, Su'an, Qianhong village
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
- 고령자
건강한 자원 봉사자를 받아들입니다
아니
설명
Inclusion Criteria:
- Age ≥ 60;
- Suffering from chronic diseases, such as hypertension, diabetes mellitus, hyperlipidemia, cardiovascular and cerebrovascular diseases, or osteoarthritis;
- Mild cognitive impairment (defined as Mini-Mental State Examination (MMSE) score of 21-26 combined with either an AD8 self-rated cognitive impairment score ≥ 2 or a digit span (backward) test (DST) score < 4);
- Mild physical impairment (defined as an Activities of Daily Living (ADL) score < 26 and a Short Physical Performance Battery (SPPB) score of 7-10).
Exclusion Criteria:
- Age <60;
- Unable to move physically;
- Already suffering from Alzheimer's disease.
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 방지
- 할당: 무작위화되지 않음
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: CM intervention group
The CM intervention was a 24-week comprehensive program integrating health education, cognitive training, and physical exercise.
The health education sessions were delivered once every four weeks, with each session lasting 30 minutes.
In contrast, cognitive training and physical exercise sessions were conducted weekly, each with a duration of 45 minutes.
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The CM intervention was a 24-week comprehensive program integrating health education, cognitive training, and physical exercise.
The health education sessions were delivered once every four weeks, with each session lasting 30 minutes.
In contrast, cognitive training and physical exercise sessions were conducted weekly, each with a duration of 45 minutes.
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간섭 없음: Control group
the group that does not receive the intervention
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Cognitive Function
기간: From enrollment to the end of intervention at 48 weeks
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Cognitive function was assessed using the Minimum Mental State Examination (MMSE) scale (Folstein, Folstein, & McHugh, 1975).The MMSE evaluates five domains: orientation, registration, attention and calculation, recall, and language abilities.
Total scores range from 0 to 30, with higher scores indicating better cognitive performance.
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From enrollment to the end of intervention at 48 weeks
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Body Mass Index
기간: From enrollment to the end of intervention at 48 weeks
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Height (cm) was measured using a wall-mounted height board, with the participant standing upright without shoes.
Weight (kg) was measured using a electronic load cell scale, with light indoor clothing and after voiding.
Body Mass Index (BMI) was calculated by dividing a person's weight in kilograms by the square of their height in meters (kg/m²).
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From enrollment to the end of intervention at 48 weeks
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Waist circumference
기간: From enrollment to the end of intervention at 48 weeks
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Waist circumference (cm) was measured using a flexible, non-elastic tape measure at the midpoint between the lowest rib and the iliac crest, with the participant standing and breathing normally.
The measurement is taken to the nearest 0.1 cm at the end of normal expiration.
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From enrollment to the end of intervention at 48 weeks
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Blood pressure
기간: From enrollment to the end of intervention at 48 weeks
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Blood pressure was assessed by measuring systolic and diastolic pressures (mmHg).
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From enrollment to the end of intervention at 48 weeks
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Activities of daily living
기간: From enrollment to the end of intervention at 48 weeks
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Activities of daily living were assessed via the Activities of daily living (ADL) scale (Ferrucci et al., 1996).
It employs a scoring range of 14 to 56, with higher scores indicating poorer functional ability.
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From enrollment to the end of intervention at 48 weeks
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Physical performance
기간: From enrollment to the end of intervention at 48 weeks
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Physical performance was assessed via the Short Physical Performance Battery (SPPB) scale (Cruz-Jentoft et al., 2010).
It has a scoring range of 0 to 12, with higher scores reflecting better physical performance.
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From enrollment to the end of intervention at 48 weeks
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Participant adherence
기간: From enrollment to the end of intervention at 48 weeks
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Participant adherence was summarized as the proportion of total participants who attended at least 50% of the intervention sessions, and separately for those who attended at least 75% of the sessions.
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From enrollment to the end of intervention at 48 weeks
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Participant satisfaction
기간: From intervention at 36 weeks to the end of intervention at 48 weeks
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Participant satisfaction was assessed using a self-developed scale, with a total score of 30 points; higher scores indicated greater satisfaction with the program.
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From intervention at 36 weeks to the end of intervention at 48 weeks
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공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (실제)
2024년 8월 15일
기본 완료 (실제)
2025년 10월 11일
연구 완료 (실제)
2025년 10월 11일
연구 등록 날짜
최초 제출
2026년 4월 26일
QC 기준을 충족하는 최초 제출
2026년 5월 13일
처음 게시됨 (실제)
2026년 5월 15일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2026년 5월 15일
QC 기준을 충족하는 마지막 업데이트 제출
2026년 5월 13일
마지막으로 확인됨
2026년 5월 1일
추가 정보
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