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BLADDER STIMULATION IN PEDIATRIC EMERGENCY DEPARTMENT

2026년 6월 12일 업데이트: Aytaç Göktuğ, Istanbul Medeniyet University

CAN THE BLADDER STIMULATION TECHNIQUE SOLVE THE URINE COLLECTION CHAOS IN THE PEDIATRIC EMERGENCY DEPARTMENT?

The purpose of this prospective, quasi-experimental study is to evaluate the efficacy of the Bladder Stimulation Technique (BST) compared to the traditional urine collection bag method in non-toilet-trained infants presenting to the Pediatric Emergency Department. The primary objective is to determine whether BST can significantly reduce urine contamination rates and the time required for successful sample collection. By comparing these two non-invasive methods, the study aims to provide a faster, cleaner, and more reliable diagnostic approach to solve the operational challenges of urine collection in acute pediatric care

연구 개요

상세 설명

Diagnosing urinary tract infections (UTIs) in non-toilet-trained infants is a daily and critical challenge in pediatric emergency departments. In this highly vulnerable group, a UTI can rapidly progress to severe complications, making an accurate diagnosis via a sterile or very clean urine sample absolutely essential. Currently, the most common non-invasive method for collecting urine from these infants is the adhesive urine bag. However, this method has significant drawbacks. Bag samples have notoriously high contamination rates-often exceeding 50%-because bacteria from the baby's skin or stool easily mix with the urine.

When a urine sample is contaminated, it frequently leads to false-positive results. This forces physicians to either prescribe unnecessary antibiotics to a very young infant or subject the baby to invasive, painful procedures like urethral catheterization to secure a sterile sample. Furthermore, waiting for an infant to naturally void into a bag is highly unpredictable, often taking hours. This waiting period increases the length of hospital stays, frustrates parents, and creates operational bottlenecks in busy emergency departments.

The Proposed Intervention: Bladder Stimulation Technique (BST) To address these clinical and operational challenges, clinicians are exploring alternative non-invasive methods. The Bladder Stimulation Technique (BST) is a safe, completely non-invasive maneuver that involves gently tapping and massaging the infant's lower abdomen (suprapubic area) and lower back (lumbar region) in a specific sequence. This gentle stimulation triggers the infant's natural reflex to urinate, allowing healthcare providers to catch a midstream urine sample directly into a sterile container.

Study Design and Methodology This is a prospective, quasi-experimental comparative study conducted in a high-volume Pediatric Emergency Department. The study is designed to directly compare the traditional adhesive urine bag method with the Bladder Stimulation Technique.

The study will specifically include infants younger than 6 months of age who present to the emergency department and require a urine sample for clinical evaluation. Eligible infants will be evaluated using one of the two collection methods, and the study will rigorously track and compare the outcomes of both approaches in real-time.

Primary and Secondary Objectives

The study focuses on three main questions regarding this specific age group:

Contamination Rates: Does BST provide a cleaner urine sample compared to the bag method in infants under 6 months, thereby significantly reducing the rate of false-positive cultures?

Time Efficiency: Does BST reduce the time required to successfully collect a urine sample compared to waiting for a bag collection?

Success Rate: What is the overall success rate of obtaining a viable urine sample using BST versus the bag method within a standard emergency room timeframe? The findings of this study have the potential to immediately change clinical guidelines and daily practices in acute pediatric care. If the Bladder Stimulation Technique proves to be faster and less prone to contamination than the traditional bag method, it will serve as a crucial "diagnostic firewall." For parents, this means less time waiting in the emergency room, protection from unnecessary antibiotic treatments, and avoiding the pain and trauma of invasive catheterization for their babies. For healthcare systems, it offers a cost-effective, evidence-based solution to resolve diagnostic dilemmas and operational bottlenecks in emergency departments.

연구 유형

중재적

등록 (추정된)

124

단계

  • 해당 없음

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 장소

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

  • 어린이

건강한 자원 봉사자를 받아들입니다

아니

설명

Inclusion Criteria:

  • Infants strictly under 6 months of age.
  • Patients presenting to the pediatric emergency department who require a urine sample collection for any clinical indication (e.g., fever without a source, suspected urinary tract infection).
  • Infants who are able to be fed orally or enterally (as the protocol requires the procedure to be performed 20 minutes after feeding to ensure bladder volume).
  • Presence of informed written consent from a parent or legal guardian.

Exclusion Criteria:

  • Infants aged 6 months or older.
  • Patients requiring immediate life-saving resuscitation or those who are hemodynamically unstable.
  • Patients with known congenital anomalies of the genitourinary tract.
  • Patients with known neurological disorders that may affect normal bladder function or voiding reflexes (e.g., neural tube defects, spina bifida).
  • Presence of skin lesions, active infections, trauma, or surgical incisions in the paravertebral (lower back) or suprapubic (lower abdomen) areas that would contraindicate physical massage and tapping.
  • Patients with any clinical contraindication to feeding.
  • Refusal of parental consent.

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

  • 주 목적: 특수 증상
  • 할당: 무작위화되지 않음
  • 중재 모델: 병렬 할당
  • 마스킹: 없음(오픈 라벨)

무기와 개입

참가자 그룹 / 팔
개입 / 치료
실험적: Arm 1: Bladder Stimulation Technique
Infants in this arm will undergo the Bladder Stimulation Technique. This completely non-invasive method involves a specific sequence of paravertebral (lower back) massage and suprapubic (lower abdomen) tapping to trigger the infant's natural voiding reflex, allowing for a midstream urine sample to be collected directly into a sterile container.
In the intervention group, the Bladder Stimulation Technique (BST) was performed. The infant was held safely suspended in the air by their armpits by a researcher to relax the abdominal muscles. The physician then initiated a stimulation cycle consisting of 30 seconds of gentle paravertebral (lower back) massage, followed immediately by 30 seconds of light suprapubic (lower abdomen) tapping. This 1-minute cycle was repeated continuously for a maximum of 5 minutes. The moment the natural voiding reflex was triggered and the infant began to urinate, a midstream urine sample was directly caught into a sterile specimen container
활성 비교기: Arm 2: Traditional Urine Bag Method
Infants in this arm will undergo the current standard of care. A standard, sterile adhesive urine collection bag will be applied to the infant's perineal area. The patient will be monitored until natural voiding occurs into the bag
The current standard care method for urine collection in non-toilet-trained infants. The infant's perineal area is cleaned, and a standard, sterile pediatric adhesive urine collection bag is attached. The infant is then closely monitored in the emergency department until spontaneous natural voiding occurs into the bag.

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
Success Rate of the Bladder Stimulation Technique and Influencing Factors
기간: From the start of the stimulation maneuver until at least 1 cc of urine is obtained (maximum of 5 minutes)
The primary objective is to evaluate the percentage of successful urine collections, strictly defined as obtaining at least 1 cc (mL) of clean-catch midstream urine, achieved specifically by using bladder stimulation maneuvers (paravertebral massage and suprapubic tapping). Additionally, this outcome evaluates the clinical and demographic factors (e.g., patient age, gender, weight) that influence the success of this specific maneuver.
From the start of the stimulation maneuver until at least 1 cc of urine is obtained (maximum of 5 minutes)

2차 결과 측정

결과 측정
측정값 설명
기간
Effect on Emergency Department Waiting Time
기간: Up to 5 minutes for the bladder stimulation group, and until at least 1 cc of urine is obtained for the traditional bag group
To evaluate and compare the effect of both urine collection methods (the bladder stimulation technique versus the traditional adhesive bag) on the total waiting time in the emergency department, measured from the initiation of the procedure until at least 1 cc of urine is successfully obtained.
Up to 5 minutes for the bladder stimulation group, and until at least 1 cc of urine is obtained for the traditional bag group

기타 결과 측정

결과 측정
측정값 설명
기간
Effect on Specimen Contamination Rates
기간: Up to 72 hours
To evaluate and compare the effect of both urine collection methods on the rates of urine culture contamination, in order to determine which method yields more reliable clinical samples.
Up to 72 hours

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (실제)

2026년 2월 1일

기본 완료 (실제)

2026년 4월 30일

연구 완료 (추정된)

2026년 6월 15일

연구 등록 날짜

최초 제출

2026년 6월 12일

QC 기준을 충족하는 최초 제출

2026년 6월 12일

처음 게시됨 (실제)

2026년 6월 17일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2026년 6월 17일

QC 기준을 충족하는 마지막 업데이트 제출

2026년 6월 12일

마지막으로 확인됨

2026년 6월 1일

추가 정보

이 연구와 관련된 용어

기타 연구 ID 번호

  • IstabulMU-PED-AG-01

개별 참가자 데이터(IPD) 계획

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아니요

약물 및 장치 정보, 연구 문서

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미국 FDA 규제 기기 제품 연구

아니

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Bladder Stimulation Technique에 대한 임상 시험

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