Myocardial Infarction With Non-obstructive Coronary Arteries in Turkish Population (MINOCA-TR)

Study population will consisted patients with acute coronary syndrome undergoing invasive diagnostic coronary angiography.

Patients will eligible to take part in the study if they will fulfilled the criteria for acute myocardial infarction.

Inclusion Criteria:

1. Patients older than 18 years

2. Evidence of an MI as defined any one of the following criteria:

   Detection of a rise and/or fall of cardiac biomarker values [preferably cardiac troponin (cTn)] with at least one value above the 99th percentile upper reference limit (URL) and with at least one of the following:

   i. Symptoms of ischaemia. ii. New or presumed new significant ST-segment-T wave (ST-T) changes or new left bundle branch block (LBBB).

   iii. Development of pathological Q waves in the ECG. iv. Imaging evidence of new loss of viable myocardium or new regional wall motion abnormality.

   v. Identification of an intracoronary thrombus by angiography.

3. Invasive diagnostic coronary angiography (IDCA) findings to allow determination of the presence /absence of obstructive coronary artery disease
4. Signed informed consent form to trial participation

Exclusion Criteria:

1. Inability/Refused to provide informed consent
2. Age below 18 years
3. Patients with unstable angina pectoris (ACS without increase and/or decrease of a cardiac biomarker, preferably high-sensitivity cardiac troponin, with at least one value above the 99th percentile of the upper reference limit)
4. Patients refused invasive diagnostic coronary angiography
5. Myocardial infarction associated with revascularization procedures