Myocardial Infarction With Non-obstructive Coronary Arteries in Turkish Population (MINOCA-TR)
The Clinical Profile, Management and Long-Term Outcomes of Patients With Acute Coronary Syndrome and Myocardial Infarction With Non-obstructive Coronary Arteries in Turkish Population
研究概览
详细说明
Acute coronary syndrome is leading causes of death worldwide. Although, >90% of these patients had of culprit coronary lesion, a significant proportion of them had no any angiographic evidence of obstructive coronary arteries. Exact mechanism of the myocardial infarction remains unclear of these patients. However, MI registries have reported that the 5% to %10 of MI patients have no evidence of obstructive coronary artery disease.
There is lack of any data regarding prevalence, demographics, patients' profile, management, and outcome of this clinical entity in Turkish population. This registry aims to obtain these data in Myocardial Infarction with Non-obstructive Coronary Artery Disease patients in Turkish population.
Although there are huge data in this issue from different country and geographic areas, to date no any national data about prevalence, demographics, management and in-hospital outcomes of AF patients who admitting with cute coronary syndrome. With this rationale the registry also aims to obtain demographics, clinical profile, management, and in-hospital outcome of AF in Turkish Acute coronary syndrome population.
研究类型
注册 (实际的)
联系人和位置
学习地点
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Izmir、火鸡
- Emin Alioğlu
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
Study population will consisted patients with acute coronary syndrome undergoing invasive diagnostic coronary angiography.
Patients will eligible to take part in the study if they will fulfilled the criteria for acute myocardial infarction.
描述
Inclusion Criteria:
- Patients older than 18 years
Evidence of an MI as defined any one of the following criteria:
Detection of a rise and/or fall of cardiac biomarker values [preferably cardiac troponin (cTn)] with at least one value above the 99th percentile upper reference limit (URL) and with at least one of the following:
i. Symptoms of ischaemia. ii. New or presumed new significant ST-segment-T wave (ST-T) changes or new left bundle branch block (LBBB).
iii. Development of pathological Q waves in the ECG. iv. Imaging evidence of new loss of viable myocardium or new regional wall motion abnormality.
v. Identification of an intracoronary thrombus by angiography.
- Invasive diagnostic coronary angiography (IDCA) findings to allow determination of the presence /absence of obstructive coronary artery disease
- Signed informed consent form to trial participation
Exclusion Criteria:
- Inability/Refused to provide informed consent
- Age below 18 years
- Patients with unstable angina pectoris (ACS without increase and/or decrease of a cardiac biomarker, preferably high-sensitivity cardiac troponin, with at least one value above the 99th percentile of the upper reference limit)
- Patients refused invasive diagnostic coronary angiography
- Myocardial infarction associated with revascularization procedures
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Composites of Myocardial Infarction, Hospitalization, Revascularization, Death
大体时间:12 months
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Re-infarction, Any cause or Cardiovascular Hospitalization or Death
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12 months
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Atrial Fibrillation
大体时间:12 months
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Any type of atrial fibrillation
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12 months
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Heart failure
大体时间:12 months
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Acute decompensated heart failure with or without cardiogenic shock
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12 months
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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