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Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs

13. juni 2020 oppdatert av: Peking Union Medical College Hospital

The acute respiratory distress syndrome(ARDS)has a high morbidity and mortality in patients admitted to intensive care units(ICUs). It represents a significant public health issue. No large nationwide, multicenters study of ARDS has been conducted in China. The purposes of this study are to analyse: 1)the incidence and outcomes of ARDS in ICU; 2) factors associated the mortality ; and 3) risk factors for development of ARDS .

Studieoversikt

Status

Fullført

Forhold

Akutt lungesviktsyndrom

Detaljert beskrivelse

All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 ) will be screened at ICU admission and daily for the occurrence of ARDS ( AECC criteria) for a maximum of 28 days after ICU admission.

Data collection:

For all patients, Demographic characteristics, admission category, the patient source intervention during ICU , APACHEII , SOFA score and discharge information will be collected
For patients with ARDS, data about ABG , parameters of MV, hemodynamic on day0 to day7 and last day of MV will be collected.
For patients without ARDS at ICU admission, data about risk factor for ARDS ,such as LIPS score, parameters of MV , and fluid balance on ICU day0 to day7 will be collected.

Studietype

Observasjonsmessig

Registrering (Faktiske)

2530

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Kina
- Beijing
  - Beijing, Beijing, Kina
    - Peking University People's Hospital
  - Beijing, Beijing, Kina, 100730
    - MICU, Peking union medical college hospital
  - Beijing, Beijing, Kina
    - Beijing Hospital of Ministry of Health
  - Beijing, Beijing, Kina
    - Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University
  - Beijing, Beijing, Kina
    - General ICU, Beijing Tongren Hospital, Capital Medical University
  - Beijng, Beijing, Kina
    - China-Japan Friendship Hospital
- Chongqing
  - ChongQing, Chongqing, Kina
    - Department of Emergency and Intensive Care Medicine, The First Affiliated Hospital of Chongqing Medical University
- Fujian
  - Fuzhou, Fujian, Kina
    - The First Affiliated Hospital of Fujian Medical University
- Guangdong
  - Guangzhou, Guangdong, Kina
    - Department of CriticalCare Medicine, Guangdong General Hospital
- Hainan
  - HaiKou, Hainan, Kina
    - Department of Critical Care Medicine, Hainan Provincial People's Hospital
- Hebei
  - Shijiazhuang, Hebei, Kina
    - Department of Critical Care Medicine, Hebei Medical University Fourth Hospital
- Heilongjiang
  - Harbin, Heilongjiang, Kina
    - Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University
- Henan
  - Zhengzhou, Henan, Kina
    - ICU, The First Affiliated Hospital, Zhengzhou University
- Hubei
  - WuHan, Hubei, Kina
    - Department of Critical Care Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science & Technology
- Hunan
  - Changsha, Hunan, Kina
    - Department of Critical Care Medicine, Xiangya Hospital, Central South University
- Inner Mongolia
  - Hohhot, Inner Mongolia, Kina
    - Department of Critical Care Medicine, The Affiliated Hopsital of Inner Mongolia Medical University
- Jilin
  - ChangChun, Jilin, Kina
    - Department of Critical Care Medicine, The Second Hospital of Jilin University
- Liaoning
  - Shenyang, Liaoning, Kina
    - Department of Critical Care Medicine, The First Affiliated Hospital of China Medical University
- Ningxia
  - YinChuan, Ningxia, Kina
    - General Hospital of Ningxia Medical University
- Shandong
  - Jinan, Shandong, Kina
    - Department of Critical Care Medicine, Qilu Hospital of Shandong University
- Shanghai
  - Shanghai, Shanghai, Kina
    - Emergency ICU, Ruijin Hospital, Shanghai Jiao Tong University
- Shanxi
  - XiAn, Shanxi, Kina
    - Surgical Intensive Care Unit, Xijing Hospital
- Sichuan
  - Chengdu, Sichuan, Kina
    - Department of Critical Care Medicine, West China Hospital, Sichuan University
- Xinjiang
  - Urumqi, Xinjiang, Kina
    - Department of Critical Care Medicine, First Affiliated Hospital, Xinjiang Medical University
- Yunnan
  - Kunming, Yunnan, Kina
    - Department of Emergency Medicine and Medical ICU, The First Affiliated Hospital of Kunming Medical University
- Zhejiang
  - Hangzhou, Zhejiang, Kina
    - Department of Critical Care Medicine, Zhejiang Provincial People's Hospital

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Alle

Prøvetakingsmetode

Ikke-sannsynlighetsprøve

Studiepopulasjon

All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 )

Beskrivelse

Inclusion Criteria:

all patients age >18 yrs admitted to 24 participating ICUs

Exclusion Criteria:

No patients should be excluded (regardless of age, underlying disease, life expectancy, etc).

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Antall grupper / kohorter

Kohorter og intervensjoner

Gruppe / Kohort
ARDS, non-ARDS patients with ARDS and patients without ARDS

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
incidence of acute respiratory distress syndrome (ARDS) Tidsramme: from ICU admission to 28-day of ICU stay	incidence of ARDS = the number of patients developing ARDS during ICU / the total number of patients admitted to ICU	from ICU admission to 28-day of ICU stay

Sekundære resultatmål

Resultatmål	Tidsramme
ICU mortality of patients with ARDS Tidsramme: followed up to 3 months after inclusion or to ICU discharge, whichever occurred first	followed up to 3 months after inclusion or to ICU discharge, whichever occurred first
hospital mortality of patients with ARDS Tidsramme: followed up to 3 months after inclusion or to hospital discharge, whichever occurred first	followed up to 3 months after inclusion or to hospital discharge, whichever occurred first

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Peking Union Medical College Hospital

Etterforskere

Hovedetterforsker: Bin Du, MICU of Peking Union Medical College Hospital

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart

1. januar 2015

Primær fullføring (Faktiske)

1. august 2015

Studiet fullført (Faktiske)

1. desember 2015

Datoer for studieregistrering

Først innsendt

18. mai 2015

Først innsendt som oppfylte QC-kriteriene

1. juli 2015

Først lagt ut (Anslag)

3. juli 2015

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

16. juni 2020

Siste oppdatering sendt inn som oppfylte QC-kriteriene

13. juni 2020

Sist bekreftet