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Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs

13 juni 2020 uppdaterad av: Peking Union Medical College Hospital

The acute respiratory distress syndrome(ARDS)has a high morbidity and mortality in patients admitted to intensive care units(ICUs). It represents a significant public health issue. No large nationwide, multicenters study of ARDS has been conducted in China. The purposes of this study are to analyse: 1)the incidence and outcomes of ARDS in ICU; 2) factors associated the mortality ; and 3) risk factors for development of ARDS .

Studieöversikt

Status

Avslutad

Betingelser

Akut respiratoriskt distress-syndrom

Detaljerad beskrivning

All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 ) will be screened at ICU admission and daily for the occurrence of ARDS ( AECC criteria) for a maximum of 28 days after ICU admission.

Data collection:

For all patients, Demographic characteristics, admission category, the patient source intervention during ICU , APACHEII , SOFA score and discharge information will be collected
For patients with ARDS, data about ABG , parameters of MV, hemodynamic on day0 to day7 and last day of MV will be collected.
For patients without ARDS at ICU admission, data about risk factor for ARDS ,such as LIPS score, parameters of MV , and fluid balance on ICU day0 to day7 will be collected.

Studietyp

Observationell

Inskrivning (Faktisk)

2530

Kontakter och platser

Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.

Studieorter

Kina
- Beijing
  - Beijing, Beijing, Kina
    - Peking University People's Hospital
  - Beijing, Beijing, Kina, 100730
    - MICU, Peking union medical college hospital
  - Beijing, Beijing, Kina
    - Beijing Hospital of Ministry of Health
  - Beijing, Beijing, Kina
    - Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University
  - Beijing, Beijing, Kina
    - General ICU, Beijing Tongren Hospital, Capital Medical University
  - Beijng, Beijing, Kina
    - China-Japan Friendship Hospital
- Chongqing
  - ChongQing, Chongqing, Kina
    - Department of Emergency and Intensive Care Medicine, The First Affiliated Hospital of Chongqing Medical University
- Fujian
  - Fuzhou, Fujian, Kina
    - The First Affiliated Hospital of Fujian Medical University
- Guangdong
  - Guangzhou, Guangdong, Kina
    - Department of CriticalCare Medicine, Guangdong General Hospital
- Hainan
  - HaiKou, Hainan, Kina
    - Department of Critical Care Medicine, Hainan Provincial People's Hospital
- Hebei
  - Shijiazhuang, Hebei, Kina
    - Department of Critical Care Medicine, Hebei Medical University Fourth Hospital
- Heilongjiang
  - Harbin, Heilongjiang, Kina
    - Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University
- Henan
  - Zhengzhou, Henan, Kina
    - ICU, The First Affiliated Hospital, Zhengzhou University
- Hubei
  - WuHan, Hubei, Kina
    - Department of Critical Care Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science & Technology
- Hunan
  - Changsha, Hunan, Kina
    - Department of Critical Care Medicine, Xiangya Hospital, Central South University
- Inner Mongolia
  - Hohhot, Inner Mongolia, Kina
    - Department of Critical Care Medicine, The Affiliated Hopsital of Inner Mongolia Medical University
- Jilin
  - ChangChun, Jilin, Kina
    - Department of Critical Care Medicine, The Second Hospital of Jilin University
- Liaoning
  - Shenyang, Liaoning, Kina
    - Department of Critical Care Medicine, The First Affiliated Hospital of China Medical University
- Ningxia
  - YinChuan, Ningxia, Kina
    - General Hospital of Ningxia Medical University
- Shandong
  - Jinan, Shandong, Kina
    - Department of Critical Care Medicine, Qilu Hospital of Shandong University
- Shanghai
  - Shanghai, Shanghai, Kina
    - Emergency ICU, Ruijin Hospital, Shanghai Jiao Tong University
- Shanxi
  - XiAn, Shanxi, Kina
    - Surgical Intensive Care Unit, Xijing Hospital
- Sichuan
  - Chengdu, Sichuan, Kina
    - Department of Critical Care Medicine, West China Hospital, Sichuan University
- Xinjiang
  - Urumqi, Xinjiang, Kina
    - Department of Critical Care Medicine, First Affiliated Hospital, Xinjiang Medical University
- Yunnan
  - Kunming, Yunnan, Kina
    - Department of Emergency Medicine and Medical ICU, The First Affiliated Hospital of Kunming Medical University
- Zhejiang
  - Hangzhou, Zhejiang, Kina
    - Department of Critical Care Medicine, Zhejiang Provincial People's Hospital

Deltagandekriterier

Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.

Urvalskriterier

Åldrar som är berättigade till studier

18 år och äldre (Vuxen, Äldre vuxen)

Tar emot friska volontärer

Nej

Kön som är behöriga för studier

Allt

Testmetod

Icke-sannolikhetsprov

Studera befolkning

All patients admitted to the participating ICUs during a 6-month period(from January 1, 2015 to July 1,2015 )

Beskrivning

Inclusion Criteria:

all patients age >18 yrs admitted to 24 participating ICUs

Exclusion Criteria:

No patients should be excluded (regardless of age, underlying disease, life expectancy, etc).

Studieplan

Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.

Hur är studien utformad?

Designdetaljer

Antal grupper/kohorter

Kohorter och interventioner

Grupp / Kohort
ARDS, non-ARDS patients with ARDS and patients without ARDS

Vad mäter studien?

Primära resultatmått

Resultatmått	Åtgärdsbeskrivning	Tidsram
incidence of acute respiratory distress syndrome (ARDS) Tidsram: from ICU admission to 28-day of ICU stay	incidence of ARDS = the number of patients developing ARDS during ICU / the total number of patients admitted to ICU	from ICU admission to 28-day of ICU stay

Sekundära resultatmått

Resultatmått	Tidsram
ICU mortality of patients with ARDS Tidsram: followed up to 3 months after inclusion or to ICU discharge, whichever occurred first	followed up to 3 months after inclusion or to ICU discharge, whichever occurred first
hospital mortality of patients with ARDS Tidsram: followed up to 3 months after inclusion or to hospital discharge, whichever occurred first	followed up to 3 months after inclusion or to hospital discharge, whichever occurred first

Samarbetspartners och utredare

Det är här du hittar personer och organisationer som är involverade i denna studie.

Sponsor

Peking Union Medical College Hospital

Utredare

Huvudutredare: Bin Du, MICU of Peking Union Medical College Hospital

Studieavstämningsdatum

Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.

Studera stora datum

Studiestart

1 januari 2015

Primärt slutförande (Faktisk)

1 augusti 2015

Avslutad studie (Faktisk)

1 december 2015

Studieregistreringsdatum

Först inskickad

18 maj 2015

Först inskickad som uppfyllde QC-kriterierna

1 juli 2015

Första postat (Uppskatta)

3 juli 2015

Uppdateringar av studier

Senaste uppdatering publicerad (Faktisk)

16 juni 2020

Senaste inskickade uppdateringen som uppfyllde QC-kriterierna

13 juni 2020

Senast verifierad