Comparative Study of Chemoradiation and Sequential Chemoradiation About Lung Adenocarcinoma Patients With Postoperative in pN2

Inclusion Criteria:

• Clinical diagnosis of Lung adenocarcinoma
• Postoperative staging pN2 period
• Voluntary participation and informed consent
• Age ≥ 18 years old, male or female, within six months of weight loss of less than 10%, can tolerate radiotherapy
• performance status( PS) score 0-2.
• Hemoglobin ≥ 80 g / L, white blood cell ≥ 4 × 109 / L, platelets ≥ 100 × 109 / L.
• Liver function: alanine aminotransferase (ALAT), aspartate transaminase (ASAT) <upper limit of normal (ULN) of 1.5 times, bilirubin <1.5 × ULN.
• Renal function: serum creatinine <1.5 × ULN.
• Compliance, and can be regular follow-up, voluntary compliance with study requirements

Exclusion Criteria:

• Do not meet the inclusion criteria
• There is evidence of distant metastases
• Suffered from other malignancies in five years
• Within the past January subjects received other drug trials
• Having serious allergies or idiosyncratic persons, such as you can not use folic acid, dexamethasone, vitamin B12 patients
• Severe lung or heart disease, a history
• Refuses or is unable to sign informed consent to participate in trials
• The abuse of drugs or alcohol addicts.
• Patients with difficult to control bacterial, viral, fungal infections
• Having a personality or mental disorders, without civil capacity or restricted civil capacity.
• Being pregnant or lactating women.