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Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise

16 de outubro de 2026 atualizado por: Gamze Altınkaynak, Saglik Bilimleri Universitesi

Relationship Between Cardiovascular Recovery After a Submaximal Exercise Test and Circadian Rhythm: A 6-Minute Walk Test-Based Study

This cross-sectional, observational, and analytical study aims to investigate the relationship between morningness-eveningness characteristics and cardiovascular recovery after a submaximal exercise test in healthy individuals aged 18-45 years. Circadian preference will be assessed using the Morningness-Eveningness Questionnaire, sleep quality will be assessed using the Pittsburgh Sleep Quality Index, and cardiovascular recovery will be evaluated following the 6-Minute Walk Test

Visão geral do estudo

Status

Recrutamento

Condições

Descrição detalhada

The study will include healthy volunteers aged 18-45 years. After written informed consent is obtained, participants will complete a sociodemographic information form, the Morningness-Eveningness Questionnaire, and the Pittsburgh Sleep Quality Index. Resting heart rate, oxygen saturation, and Borg dyspnea/fatigue scores will then be recorded, followed by the 6-Minute Walk Test. Physiological measurements will be repeated immediately after the test and at the 1st, 3rd, and 5th minutes of recovery.

The planned sample size is at least 124 participants. This was calculated using G*Power 3.1.9.7 based on a medium effect size (r=0.30), a significance level of 5% (α=0.05), and 90% statistical power, with an additional 10% allowance for possible data loss or missing data. Data will be analyzed using descriptive statistics, normality analyses, appropriate parametric or non-parametric comparison tests, correlation analyses, and multivariable regression analyses, with statistical significance set at p<0.05.

Tipo de estudo

Observacional

Inscrição (Estimado)

124

Contactos e Locais

Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.

Contato de estudo

Nome: Gamze Koyutürk, Asst Prof
Número de telefone: +905065798671
E-mail: gamzealtinkaynak@gmail.com

Estude backup de contato

Nome: Mehmet Burak Uyaroğlu, Asst Prof
Número de telefone: 5396545352
E-mail: m.uyaroglu1@gmail.com

Locais de estudo

Turquia (Türkiye)
- - Istanbul, Turquia (Türkiye)
    - Recrutamento
    - İstanbul Topkapı University
    - Contato:
      
      Gamze Koyutürk, Asst. Prof
      
      Número de telefone: 5065798671
      
      E-mail: gamzekoyuturk@topkapi.edu.tr

Critérios de participação

Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.

Critérios de elegibilidade

Idades elegíveis para estudo

18 anos a 45 anos (Adulto)

Aceita Voluntários Saudáveis

Sim

Gêneros Elegíveis para o Estudo

Tudo

Método de amostragem

Amostra Não Probabilística

População do estudo

Healthy volunteers aged 18-45 years who meet the study eligibility criteria and agree to participate voluntarily.

Descrição

Inclusion Criteria:

Aged 18-45 years.
Being healthy.
Voluntarily agreeing to participate in the study.

Exclusion Criteria:

Presence of cardiovascular, pulmonary, neurological, or orthopedic disease.
Having a health problem that prevents exercise.
Use of medication that may affect exercise tolerance.
Pregnancy.

Plano de estudo

Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.

Como o estudo é projetado?

Detalhes do projeto

Modelos de observação: COHORT
Perspectivas de Tempo: PROSPECTIVE

Número de grupos/coortes

Coortes e Intervenções

Grupo / Coorte
Single Group Healthy volunteers aged 18-45 years. Participants will complete a sociodemographic information form, the Morningness-Eveningness Questionnaire, and the Pittsburgh Sleep Quality Index. Resting heart rate, oxygen saturation, and Borg dyspnea/fatigue scores will be recorded, followed by the 6-Minute Walk Test. Physiological measurements will also be obtained immediately after the test and at the 1st, 3rd, and 5th minutes of recovery. No intervention will be administered

Grupo / Coorte

Single Group

Healthy volunteers aged 18-45 years. Participants will complete a sociodemographic information form, the Morningness-Eveningness Questionnaire, and the Pittsburgh Sleep Quality Index. Resting heart rate, oxygen saturation, and Borg dyspnea/fatigue scores will be recorded, followed by the 6-Minute Walk Test. Physiological measurements will also be obtained immediately after the test and at the 1st, 3rd, and 5th minutes of recovery. No intervention will be administered

O que o estudo está medindo?

Medidas de resultados primários

Medida de resultado	Descrição da medida	Prazo
Heart Rate Recovery After the 6-Minute Walk Test Prazo: Baseline and up to 5 minutes post-exercise	Heart rate will be recorded at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of the recovery period to evaluate cardiovascular recovery following submaximal exercise.	Baseline and up to 5 minutes post-exercise

Medidas de resultados secundários

Medida de resultado	Descrição da medida	Prazo
Oxygen Saturation (SpO₂) During Post-Exercise Recovery Prazo: Up to 5 minutes after the 6-Minute Walk Test	Oxygen saturation will be recorded at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of recovery.	Up to 5 minutes after the 6-Minute Walk Test
Borg Dyspnea/Fatigue Score During Post-Exercise Recovery Prazo: Baseline and up to 5 minutes post-exercise	Dyspnea and fatigue will be assessed using the Borg Dyspnea/Fatigue Scale at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of recovery.	Baseline and up to 5 minutes post-exercise
Morningness-Eveningness Characteristics Prazo: Baseline	The Morningness-Eveningness Questionnaire assesses individuals' preference for the timing of sleep and daily activities. Scores range from 16 to 86, with higher scores indicating a stronger morning preference and lower scores indicating a stronger evening preference, rather than better or worse outcomes.	Baseline
Sleep Quality Prazo: Baseline	Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI), which evaluates sleep quality and disturbances over the past month. The global score ranges from 0 to 21, with higher scores indicating poorer sleep quality.	Baseline

Colaboradores e Investigadores

É aqui que você encontrará pessoas e organizações envolvidas com este estudo.

Patrocinador

Saglik Bilimleri Universitesi

Investigadores

Investigador principal: Gamze Koyutürk, Asst Prof, Topkapı University
Diretor de estudo: Mehmet B Uyaroğlu, Asst Prof, Fenerbahce University
Cadeira de estudo: Beyza Erdoğmuş, Dr
Cadeira de estudo: Hüsna Güzel, MsC, Fenerbahce University

Datas de registro do estudo

Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.

Datas Principais do Estudo

Início do estudo (Estimado)

1 de outubro de 2026

Conclusão Primária (Estimado)

31 de março de 2027

Conclusão do estudo (Estimado)