Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya Patients
20 maj 2026 uppdaterad av: Maria Cláudia Valente Almeida, Universidade do Estado do Pará
Effects Of A Rehabilitation Protocol On Muscle Strength, Muscle Fatigue And Postural Control In Post-Dengue And Chikungunya Patients: Non-Randomized Clinical Trial
Introduction: Dengue and Chikungunya arboviral diseases are considered major public health challenges in tropical regions due to high infection rates and the occurrence of musculoskeletal sequelae that impair strength, balance, and functionality.
After the acute phase, symptoms such as fatigue, joint pain, muscle weakness, and postural instability are common, reducing quality of life and hindering social and occupational reintegration.Objective: To analyze the effects of a rehabilitation protocol on muscle fatigue, muscle strength, and postural control in post-Dengue and Chikungunya patients.Methods:
This is a non-randomized clinical trial conducted at the Integrated Laboratory for Research and Care in Infectious and Sequelae Diseases (LabDIS/UEPA).
Individuals of both sexes, aged over 18 years, with a confirmed diagnosis of Dengue and/or Chikungunya within the last five years will be included.
Data collection will include a clinical interview, surface electromyography of the flexor carpi radialis, tibialis anterior, lateral and medial gastrocnemius muscles, hydraulic and electronic dynamometry, manovacuometry, and baropodometry.
The rehabilitation protocol will consist of twenty supervised sessions of aerobic, anaerobic, and respiratory exercises.Expected Results: Improvements in muscle strength, muscle fatigue, and postural control are expected following the intervention.Conclusion:
The findings may support physiotherapeutic strategies aimed at improving strength, fatigue, and balance, expanding knowledge on the neuromuscular and respiratory consequences of arboviral diseases, and contributing to the development of evidence-based rehabilitation protocols, with potential positive impacts on healthcare delivery and public health policies.
Studieöversikt
Status
Har inte rekryterat ännu
Betingelser
Intervention / Behandling
Studietyp
Interventionell
Inskrivning (Beräknad)
54
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studiekontakt
- Namn: Maria Cláudia V Almeida, Principal Investigator
- Telefonnummer: +55 (91) 99102-9191
- E-post: maria.cv.almeid@aluno.uepa.br
Studieorter
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Pará
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Belém, Pará, Brasilien, 66.087-670
- Universidade do Estado do Pará
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Kontakt:
- Márcio C de souza santos, Coordinator
- Telefonnummer: +55 (91) 98134-9895
- E-post: marcio.clementino@gmail.com
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Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
- Äldre vuxen
Tar emot friska volontärer
Nej
Beskrivning
Inclusion Criteria:
- Adults aged 18 years or older
- Individuals of both sexes
- Residents of the 1st, 4th, or 11th Health Regions of the state of Pará
- Confirmed diagnosis of Dengue (DENV) and/or Chikungunya (CHIKV) infection by serological testing (ELISA or IgG/IgM)
- Diagnosis confirmed within the last 5 years
- Ability to provide written informed consent
Exclusion Criteria:
- Hemodynamic instability
- Musculoskeletal instability, including fractures or acute muscle injuries
- Cognitive deficits impairing the understanding of commands or study procedures
- History of balance disorders prior to Dengue or Chikungunya infection
- Obesity
- Blindness or low vision
- Hearing impairment
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: N/A
- Interventionsmodell: Sekventiell tilldelning
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
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Experimentell: Intervention Group
Post-Dengue And Chikungunya Patients
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The rehabilitation protocol will include 20 sessions, twice weekly.
Anaerobic training will involve vertical chest press, lat pulldown, leg extension, and 180° leg press, with a prior 1RM test.
Sessions 1-5 and 11-15: 3 sets of 12 reps at 55% 1RM; sessions 6-10 and 16-20: 3 sets of 15 reps at 55% 1RM.
Aerobic training will be performed on a treadmill or cycle ergometer, progressing from 41-50% HRR (sessions 1-5), 51-60% (6-10), 61-70% (11-15), and 71-80% (16-20).
Respiratory training will use the PowerBreathe® device: sessions 1-10 at 30% MIP with 10 repetitions, and sessions 11-20 at 40% MIP with 10 repetitions.
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Muscle fatigue assessed by surface electromyography
Tidsram: Baseline and immediately after completion of the intervention protocol
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Surface electromyography (EMG) will be used to evaluate muscle activity and fatigue of the flexor carpi radialis, tibialis anterior, medial gastrocnemius, and lateral gastrocnemius muscles using the New Miotool Wireless® system.
Muscle fatigue will be analyzed through Mean Frequency (MNF) slope during sustained isometric contraction
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Baseline and immediately after completion of the intervention protocol
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Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
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Handgrip strength assessed by hydraulic dynamometry
Tidsram: Baseline and immediately after completion of the intervention protocol
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Handgrip strength will be measured using a calibrated Crown® hydraulic hand dynamometer following the American Society of Hand Therapists (ASHT) recommendations.
Maximal isometric grip strength will be recorded in kilogram-force (kgf).
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Baseline and immediately after completion of the intervention protocol
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Peripheral muscle strength assessed by electronic dynamometry
Tidsram: Baseline and immediately after completion of the intervention protocol
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Maximum isometric muscle strength of wrist flexors/extensors and ankle dorsiflexors/plantar flexors will be assessed using the MedEOR Medtech® digital dynamometer.
Strength values will be recorded in kilogram-force (kgf).
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Baseline and immediately after completion of the intervention protocol
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Postural control assessed by baropodometry
Tidsram: Baseline and immediately after completion of the intervention protocol
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Postural control and plantar pressure distribution will be evaluated using the Footwork Pro AM³ pressure platform.
Stabilometric variables will include center of pressure displacement, oscillation area, and postural sway under eyes-open and eyes-closed conditions.
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Baseline and immediately after completion of the intervention protocol
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Respiratory muscle strength assessed by manovacuometry
Tidsram: Baseline and immediately after completion of the intervention protocol
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Respiratory muscle strength will be assessed using a digital manovacuometer (MVD300-U).
Maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) will be measured in cmH₂O.
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Baseline and immediately after completion of the intervention protocol
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Samarbetspartners och utredare
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Sponsor
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Beräknad)
1 juli 2026
Primärt slutförande (Beräknad)
1 juli 2027
Avslutad studie (Beräknad)
30 juli 2027
Studieregistreringsdatum
Först inskickad
7 maj 2026
Först inskickad som uppfyllde QC-kriterierna
14 maj 2026
Första postat (Faktisk)
22 maj 2026
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
26 maj 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
20 maj 2026
Senast verifierad
1 maj 2026
Mer information
Termer relaterade till denna studie
Nyckelord
Ytterligare relevanta MeSH-villkor
- Vektorburna sjukdomar
- Myggburna sjukdomar
- Infektioner
- RNA-virusinfektioner
- Virussjukdomar
- Arbovirusinfektioner
- Flavivirusinfektioner
- Flaviviridae-infektioner
- Hemorragiska feber, Viral
- Alfavirusinfektioner
- Togaviridae-infektioner
- Dengue
- Chikungunya feber
- Motorisk aktivitet
- Rörelse
- Muskuloskeletala fysiologiska fenomen
- Muskuloskeletala och neurala fysiologiska fenomen
- Utöva
Andra studie-ID-nummer
- 7.646.502
Plan för individuella deltagardata (IPD)
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OBESLUTSAM
IPD-planbeskrivning
For statistical analysis purposes, the data may be shared with the study advisor.
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