CIMT Versus HABIT in Late Sub-Acute Post-Stroke Rehabilitation (CIMT-HABIT)
1 juni 2026 uppdaterad av: Riphah International University
Comparative Effects of Constraint Induced Movement Therapy and Hand-Arm Bimanual Intensive Training for Upper Extremity Function in Late Sub-Acute Post-Stroke Patients
This study will compare the effects of Constraint Induced Movement Therapy and Hand-Arm Bimanual Intensive Training on upper extremity function in late sub-acute post-stroke patients.
It will be a randomized controlled trial.
Eligible participants will be randomly allocated into two groups.
One group will receive Constraint Induced Movement Therapy, while the other group will receive Hand-Arm Bimanual Intensive Training.
Both groups will also receive standard physiotherapy for mobility and postural control.
The intervention will continue for 3 weeks.
Outcomes will be assessed at baseline and after the intervention using upper limb function and motor control assessment tools.
Studieöversikt
Status
Aktiv, inte rekryterande
Betingelser
Intervention / Behandling
Detaljerad beskrivning
Stroke commonly affects upper extremity function and may reduce a patient's ability to perform daily activities independently.
In the late sub-acute phase after stroke, structured rehabilitation may help improve arm and hand function, motor control, and real-world use of the affected upper limb.
Constraint Induced Movement Therapy encourages use of the affected upper limb by restricting the unaffected arm and providing intensive task-oriented training.
Hand-Arm Bimanual Intensive Training focuses on coordinated use of both hands through functional bimanual tasks.
This study will compare these two rehabilitation approaches in late sub-acute post-stroke patients.
Findings may help guide evidence-based selection of upper limb rehabilitation strategies for improving functional recovery after stroke.
Studietyp
Interventionell
Inskrivning (Beräknad)
34
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studieorter
-
-
Punjab Province
-
Lahore, Punjab Province, Pakistan, 55100
- Riphah College of Rehabilitation Sciences
-
-
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
- Äldre vuxen
Tar emot friska volontärer
Nej
Beskrivning
Inclusion Criteria:
Adults aged 40 years and above.
- Diagnosed with unilateral ischemic or hemorrhagic stroke.
- Stroke duration between 3 to 6 months.
- Mini-Mental State Examination score of 24 or above.
- Able and willing to provide informed consent.
Exclusion Criteria:
Severe pain in the more affected upper limb on verbal rating scale.
- Spasticity greater than 3 on the Modified Ashworth Scale in the affected upper limb.
- Unstable cardiovascular conditions.
- Any traumatic musculoskeletal injury of the upper limb.
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Enda
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
|
Experimentell: Constraint Induced Movement Therapy Group
Participants in this arm will receive Constraint Induced Movement Therapy for 3 weeks.
The unaffected arm will be constrained with a mitt for 90% of waking hours, and the affected arm will receive intensive task-oriented training for 2 hours per day, 5 days per week.
Training tasks will include reaching, grasping, manipulating, dressing, and eating activities.
Participants will also receive standard physiotherapy for mobility and postural control.
|
Constraint Induced Movement Therapy will be provided for 3 weeks.
The unaffected upper limb will be constrained with a mitt for 90% of waking hours.
Participants will receive intensive task-oriented training of the affected upper limb for 2 hours per day, 5 days per week.
Activities will include reaching, grasping, manipulating objects, dressing, and eating tasks.
Standard physiotherapy for mobility and postural control will also be provided.
Andra namn:
|
|
Aktiv komparator: Hand-Arm Bimanual Intensive Training Group
Participants in this arm will receive Hand-Arm Bimanual Intensive Training for 3 weeks.
Training will be provided for 2 hours per day, 5 days per week, using symmetrical and asymmetrical bimanual activities such as folding clothes and pouring water.
Participants will also receive standard physiotherapy for mobility and postural control.
|
Hand-Arm Bimanual Intensive Training will be provided for 3 weeks.
Participants will receive supervised bimanual upper limb training for 2 hours per day, 5 days per week.
Activities will include symmetrical and asymmetrical bilateral tasks such as folding clothes, pouring water, object transfer, and coordinated hand use.
Standard physiotherapy for mobility and postural control will also be provided.
|
Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Fugl-Meyer Assessment - Upper Extremity (FMA-UE)
Tidsram: Baseline and Week 3 (Post-intervention)
|
Measures motor recovery and voluntary movement of the affected upper limb after stroke.
|
Baseline and Week 3 (Post-intervention)
|
|
Action Research Arm Test (ARAT)
Tidsram: Baseline and Week 3 (Post-intervention)
|
Assesses upper extremity functional ability including grasp, grip, pinch, and gross movement.
|
Baseline and Week 3 (Post-intervention)
|
Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Motor Activity Log (MAL)
Tidsram: Baseline and Week 3
|
Evaluates real-world use of the affected arm including Amount of Use and Quality of Movement.
|
Baseline and Week 3
|
|
Box and Block Test (BBT)
Tidsram: Baseline and Week 3
|
Assesses gross manual dexterity by counting blocks transferred within 60 seconds.
|
Baseline and Week 3
|
|
Jebsen-Taylor Hand Function Test (JTHFT)
Tidsram: Baseline and Week 3
|
Measures functional hand performance during simulated daily activities.
|
Baseline and Week 3
|
|
Adult Assisting Hand Assessment (Ad-AHA)
Tidsram: Baseline and Week 3
|
Measures effectiveness of affected hand use during bimanual task performance.
|
Baseline and Week 3
|
Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Utredare
- Studiestol: Ambreen I IQBAL, Riphah International University Role
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Faktisk)
5 juni 2025
Primärt slutförande (Beräknad)
6 juli 2026
Avslutad studie (Beräknad)
6 augusti 2026
Studieregistreringsdatum
Först inskickad
1 juni 2026
Först inskickad som uppfyllde QC-kriterierna
1 juni 2026
Första postat (Faktisk)
4 juni 2026
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
4 juni 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
1 juni 2026
Senast verifierad
1 juni 2026
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- HAFSA LATIF
Plan för individuella deltagardata (IPD)
Planerar du att dela individuella deltagardata (IPD)?
NEJ
IPD-planbeskrivning
Individual participant data will not be shared because no formal data-sharing mechanism or repository has been established for this academic study.
Participant confidentiality and privacy will be maintained.
Läkemedels- och apparatinformation, studiedokument
Studerar en amerikansk FDA-reglerad läkemedelsprodukt
Nej
Studerar en amerikansk FDA-reglerad produktprodukt
Nej
Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .