Association of Maternal Thyroid Function and Anxiety With Fetal Cardiotocography Parameters in High-Risk Pregnancies
Association Between Maternal Thyroid Functions, Anxiety Levels, and Fetal Cardiotocography Parameters in High-Risk Pregnancies
This prospective observational study aims to investigate the association between maternal thyroid function, maternal anxiety levels, and fetal cardiotocography parameters in high-risk pregnancies. Pregnant women at 32 weeks of gestation or later who are followed in the perinatology outpatient clinic for high-risk pregnancy will be included.
Maternal thyroid function test results, including thyroid-stimulating hormone (TSH) and free thyroxine (fT4), obtained as part of routine clinical care will be recorded. Maternal anxiety will be assessed using the Beck Anxiety Inventory. Fetal well-being will be evaluated using a routine 20-minute non-stress test (NST), including baseline fetal heart rate, accelerations, reactivity, and the presence of decelerations.
The associations between maternal anxiety scores, thyroid hormone levels and thyroid status, and fetal cardiotocography parameters will be analyzed. Sociodemographic and obstetric characteristics will also be evaluated in relation to these parameters.
Studieöversikt
Status
Betingelser
Studietyp
Inskrivning (Beräknad)
Kontakter och platser
Studiekontakt
- Namn: Doruk C Katlan
- Telefonnummer: +905353475411
- E-post: dcek2000@yahoo.com
Studieorter
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Istanbul, Turkiet (Türkiye)
- Rekrytering
- Istanbul Training and Research Hospital
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Kontakt:
- Doruk C Katlan
- Telefonnummer: +905353475411
- E-post: dcek2000@yahoo.com
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Underutredare:
- Nebahat Uzunay
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Underutredare:
- Filiz Değirmenci
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Deltagandekriterier
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
Tar emot friska volontärer
Testmetod
Studera befolkning
Beskrivning
Inclusion Criteria:
- Singleton pregnancy at 32 weeks of gestation or later
- Pregnancy being followed as a high-risk pregnancy
- Age between 18 and 45 years
- Availability of routine thyroid function test results and non-stress test assessment
- Ability and willingness to provide written informed consent
Exclusion Criteria:
- Gestational age below 32 weeks
- Multiple pregnancy
- Fetal conditions that may affect interpretation of the non-stress test tracing
- Acute maternal infection
- Presence of an acute obstetric condition
- Previously diagnosed psychiatric disorder
- Current use of psychiatric medication
- Age younger than 18 years or older than 45 years
Studieplan
Hur är studien utformad?
Designdetaljer
Kohorter och interventioner
Grupp / Kohort |
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High-Risk Pregnant Women
Pregnant women with singleton high-risk pregnancies at 32 weeks of gestation or later who undergo routine thyroid function testing and non-stress testing as part of their clinical follow-up.
Maternal anxiety will be assessed using the Beck Anxiety Inventory.
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
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Association Between Maternal Anxiety Level and NST Parameters
Tidsram: At study enrollment, during the same-day assessment
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The association between Beck Anxiety Inventory scores and fetal non-stress test parameters will be evaluated.
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At study enrollment, during the same-day assessment
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Association Between Maternal Thyroid Function and NST Parameters
Tidsram: At study enrollment, using third-trimester thyroid function test results and same-day NST assessment
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The association between maternal TSH and free T4 levels and fetal non-stress test parameters will be evaluated.
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At study enrollment, using third-trimester thyroid function test results and same-day NST assessment
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Sekundära resultatmått
Resultatmått |
Tidsram |
|---|---|
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Association of Sociodemographic and Obstetric Characteristics With Maternal Anxiety, Thyroid Function, and NST Parameters
Tidsram: At study enrollment, using third-trimester thyroid function test results and same-day NST and anxiety assessment
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At study enrollment, using third-trimester thyroid function test results and same-day NST and anxiety assessment
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Samarbetspartners och utredare
Studieavstämningsdatum
Studera stora datum
Studiestart (Faktisk)
Primärt slutförande (Beräknad)
Avslutad studie (Beräknad)
Studieregistreringsdatum
Först inskickad
Först inskickad som uppfyllde QC-kriterierna
Första postat (Faktisk)
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
Senast verifierad
Mer information
Termer relaterade till denna studie
Nyckelord
Andra studie-ID-nummer
- ISTANBUL TRH - 27.03.2026-100
Plan för individuella deltagardata (IPD)
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