Malaria Incidence in Infants in Bancoumana, Mali
This study, conducted by the Malaria Research and Training Center at the Faculty of Medicine in Bamako and the NIAID will measure the frequency of occurrence of malaria in infants in Bancoumana, Mali. Information from the study will help in planning trials of malaria vaccines.
Healthy children from 6 weeks to 6 months of age who live in the Bancoumana health area may be eligible for this study. Candidates are screened with a physical examination and blood tests.
Participating children are visited at home for a total of about 17 visits to see if they are well. They come to the clinic every month during the 7-month study for a clinical evaluation, including a blood sample obtained by finger prick to test for malaria. Some of the blood collected may be stored and used for research. Children who become sick with malaria are treated for the disease.
研究概览
地位
详细说明
研究类型
注册 (预期的)
联系人和位置
学习地点
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Maryland
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Bethesda、Maryland、美国、20892
- National Institute of Allergy and Infectious Diseases (NIAID), 9000 Rockville Pi
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
INCLUSION CRITERIA:
- Infants at least six weeks to less than 7 months of age at enrollment
- Known residents of the Bancoumana health area
- Good general health as determined by clinical exam
- Available for the 6-7 months duration of the trial
- Willingness to participate as evidenced by signing of the informed consent or fingerprinting by the parent or guardian
EXCLUSION CRITERIA:
- Social, behavioral, cognitive, or psychiatric condition that in the opinion of the investigator affects the ability of the volunteer or the parent/legal guardian to understand and cooperate with the study protocol
- Participation in an investigational vaccine or drug trial within 30 days of starting this study, or while this study is ongoing
- Infant born to mother with known or suspected HIV/AIDS as determined by the clinician
学习计划
研究是如何设计的?
设计细节
- 时间观点:预期
合作者和调查者
出版物和有用的链接
一般刊物
- Duflo B, Balique H, Ranque P, Diallo AN, Brucker G, Alavi H, Prescott N. [Estimation of the impact of the principal diseases in rural Mali]. Rev Epidemiol Sante Publique. 1986;34(6):405-18. French.
- Wagner G, Koram K, McGuinness D, Bennett S, Nkrumah F, Riley E. High incidence of asymptomatic malara infections in a birth cohort of children less than one year of age in Ghana, detected by multicopy gene polymerase chain reaction. Am J Trop Med Hyg. 1998 Jul;59(1):115-23. doi: 10.4269/ajtmh.1998.59.115.
- Moody AH, Chiodini PL. Non-microscopic method for malaria diagnosis using OptiMAL IT, a second-generation dipstick for malaria pLDH antigen detection. Br J Biomed Sci. 2002;59(4):228-31. doi: 10.1080/09674845.2002.11783665.
研究记录日期
研究主要日期
学习开始
研究完成
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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