Clinical Concordance Study Between Watson for Oncology and Clinician Practice (W001)
2018年1月17日 更新者：Xiaochun Zhang、Qingdao University
A Retrospective, Self - Controlled, Single - Center Clinical Concordance Study Between Watson for Oncology and Clinician Practice
At present, Watson for Oncology has been applied in 14 countries worldwide, including China, the United States, Holland, Thailand, India, Korea, Poland, Slovakia and Bangladesh.
In a double-blind study involving 362 patients in India, treatment recommendations from Watson for Oncology (WFO) performed a high degree of consistency with their multidisciplinary tumor board.
The investigators would recruit cancer patients diagnosed as lung cancer, breast cancer, gastric cancer, colon cancer， rectal cancer，cervical cancer or ovarian cancer according to the criteria of Watson for Oncology ，using the updated version of Watson for Oncology to explore the concordance of therapeutic regimen between WFO and physicians in the Affiliated Hospital of Qingdao University.
研究概览
详细说明
This study was approved by the Affiliated Hospital of Qingdao University ethics committee.The investigators would randomly selected cancer patients, including lung cancer, breast cancer, gastric cancer, colon cancer，rectal cancer，cervical cancer and ovarian cancer patients, from the Affiliated Hospital of Qingdao University database according to the criteria of Watson for Oncology(supplementary materials).
Case data would be extracted and input into the Watson system.
WFO provided therapeutic recommendations in three categories: recommended, for consideration, and not recommended.
Data would be analyzed retrospectively to compare the WFO's recommendations and actual therapeutic regimen in the hospital.
Some actual regimen applications that were not available in WFO will be defined as "physician's choice".
Overall, physician's recommendations would be defined as concordant with WFO if they corresponded to the recommended or consideration categories and as non-concordant if they corresponded to the not recommended or not available categories.
研究类型
观察性的
注册 (预期的)
350
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
Shandong
-
Qingdao、Shandong、中国
- 招聘中
- The Affiliated Hospital of Qingdao University
-
接触：
- Xiaoxhun Zhang
- 电话号码：086053282913271
- 邮箱：zxc9670@126.com
-
首席研究员：
- Xiaochun Zhang
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 至 90年 (成人、年长者)
接受健康志愿者
不
有资格学习的性别
全部
取样方法
概率样本
研究人群
cancer patients from outpatient and inpatient in our hospital
描述
Inclusion Criteria:
- a histology of lung cancer,breast cancer,gastric cancer, colon cancer， rectal cancer，cervical cancer and ovarian cancer
- had no prior systemic therapy and need neoadjuvant/adjuvant or metastatic therapy
- had prior neoadjuvant therapy, adjuvant therapy and/or surgery and are now metastatic
- have had prior surgery and now need adjuvant therapy
- seeking an additional therapy whose cancer has progressed beyond its initial metastatic therapy (second line)
Exclusion Criteria:
- not have confirmed diagnoses of invasive cancer
- under 18 years of age
- pregnant
- with multiple concurrent primary cancers or a local recurrence or a new primary at the same site of a previously treated cancer
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
concordance
大体时间：Day 0
|
the concordance of therapeutic regimen between WFO and physicians in the Affiliated Hospital of Qingdao University
|
Day 0
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2017年4月12日
初级完成 (预期的)
2018年12月31日
研究完成 (预期的)
2019年1月31日
研究注册日期
首次提交
2017年12月21日
首先提交符合 QC 标准的
2018年1月9日
首次发布 (实际的)
2018年1月17日
研究记录更新
最后更新发布 (实际的)
2018年1月18日
上次提交的符合 QC 标准的更新
2018年1月17日
最后验证
2018年1月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.