- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03400514
Clinical Concordance Study Between Watson for Oncology and Clinician Practice (W001)
January 17, 2018 updated by: Xiaochun Zhang, Qingdao University
A Retrospective, Self - Controlled, Single - Center Clinical Concordance Study Between Watson for Oncology and Clinician Practice
At present, Watson for Oncology has been applied in 14 countries worldwide, including China, the United States, Holland, Thailand, India, Korea, Poland, Slovakia and Bangladesh.
In a double-blind study involving 362 patients in India, treatment recommendations from Watson for Oncology (WFO) performed a high degree of consistency with their multidisciplinary tumor board.
The investigators would recruit cancer patients diagnosed as lung cancer, breast cancer, gastric cancer, colon cancer, rectal cancer,cervical cancer or ovarian cancer according to the criteria of Watson for Oncology ,using the updated version of Watson for Oncology to explore the concordance of therapeutic regimen between WFO and physicians in the Affiliated Hospital of Qingdao University.
Study Overview
Status
Unknown
Conditions
Detailed Description
This study was approved by the Affiliated Hospital of Qingdao University ethics committee.The investigators would randomly selected cancer patients, including lung cancer, breast cancer, gastric cancer, colon cancer,rectal cancer,cervical cancer and ovarian cancer patients, from the Affiliated Hospital of Qingdao University database according to the criteria of Watson for Oncology(supplementary materials).
Case data would be extracted and input into the Watson system.
WFO provided therapeutic recommendations in three categories: recommended, for consideration, and not recommended.
Data would be analyzed retrospectively to compare the WFO's recommendations and actual therapeutic regimen in the hospital.
Some actual regimen applications that were not available in WFO will be defined as "physician's choice".
Overall, physician's recommendations would be defined as concordant with WFO if they corresponded to the recommended or consideration categories and as non-concordant if they corresponded to the not recommended or not available categories.
Study Type
Observational
Enrollment (Anticipated)
350
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Shandong
-
Qingdao, Shandong, China
- Recruiting
- The Affiliated Hospital of Qingdao University
-
Contact:
- Xiaoxhun Zhang
- Phone Number: 086053282913271
- Email: zxc9670@126.com
-
Principal Investigator:
- Xiaochun Zhang
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 90 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
cancer patients from outpatient and inpatient in our hospital
Description
Inclusion Criteria:
- a histology of lung cancer,breast cancer,gastric cancer, colon cancer, rectal cancer,cervical cancer and ovarian cancer
- had no prior systemic therapy and need neoadjuvant/adjuvant or metastatic therapy
- had prior neoadjuvant therapy, adjuvant therapy and/or surgery and are now metastatic
- have had prior surgery and now need adjuvant therapy
- seeking an additional therapy whose cancer has progressed beyond its initial metastatic therapy (second line)
Exclusion Criteria:
- not have confirmed diagnoses of invasive cancer
- under 18 years of age
- pregnant
- with multiple concurrent primary cancers or a local recurrence or a new primary at the same site of a previously treated cancer
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
concordance
Time Frame: Day 0
|
the concordance of therapeutic regimen between WFO and physicians in the Affiliated Hospital of Qingdao University
|
Day 0
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
April 12, 2017
Primary Completion (Anticipated)
December 31, 2018
Study Completion (Anticipated)
January 31, 2019
Study Registration Dates
First Submitted
December 21, 2017
First Submitted That Met QC Criteria
January 9, 2018
First Posted (Actual)
January 17, 2018
Study Record Updates
Last Update Posted (Actual)
January 18, 2018
Last Update Submitted That Met QC Criteria
January 17, 2018
Last Verified
January 1, 2018
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- XCZhang001
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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