The Fasting and Shifted Timing (FAST) of Eating Study (FAST)
研究概览
详细说明
Fasting and time-restricted feeding (TRF) have become increasingly popular in nutrition research due to the potential health benefits they may provide. Several animal studies, and more recently some human studies, have indicated regular meal-timing (i.e. eating mostly in the day) or fasting have been beneficial for controlling weight, blood pressure, cholesterol, glucose, and insulin sensitivity.
These types of eating patterns may offer the same "anti-aging" health benefits as traditional caloric restriction (i.e. consistent and routine adherence to a very low-calorie diet).While caloric restriction is considered the gold standard for weight management, weight regain often limits the long-term effectiveness of this approach. People often experience increases in hunger, which make it difficult to sustain this type of behavior.Therefore, researchers are turning to these dietary approaches as alternatives to low-calorie diets in an effort to obtain the same benefits, but with less burden on participants.
However, it is not clear if the adherence to these types of diet protocols are any better than a low-calorie diet. Would people be more satisfied with meal-timing or fasting over a traditional very low-calorie diet? That is the main research question of this study.
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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South Carolina
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Columbia、South Carolina、美国、29208
- University of South Carolina
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Be 18 years or older.
- Have a BMI between 25 - 49.9 kg/m2.
- Have a scale at home, or some way of weighing yourself regularly, so that you can report your body weight to the research staff.
- Be able to check emails regularly, because all of the surveys need to be completed online.
Exclusion Criteria:
- NOT be already practicing any of these fasting approaches.
- NOT currently diagnosed with diabetes.
- NOT taking any appetite suppressants or prescription weight loss medications.
- NOT planning on getting pregnant within the next 6 weeks.
- Do NOT currently have any eating disorders.
- Have NOT lost or gained a significant amount of weight (i.e. 10 pounds or more) within the last 6 months.
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:非随机化
- 介入模型:交叉作业
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的:Time-restricted feeding (TRF)
Participants will eat the majority of their calories in the day.
More specifically participants will consume 70% of their total calories before 5 pm and the remaining 30% after 5 pm.
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Participants will receive handouts via email about how to follow each diet
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有源比较器:Intermittent fasting (IF)
This involves eating all of one's meals within a specific time (e.g. 8 hours) frame and fasting for the remaining hours (16 hours) in a day.
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Participants will receive handouts via email about how to follow each diet
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有源比较器:Alternate day fasting (ADF)
This involves complete fasting (i.e.
no food or caloric containing beverages, only water consumption) for roughly an entire 36-hour period, followed by an ad libitum feeding day.
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Participants will receive handouts via email about how to follow each diet
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Weight loss-week 1
大体时间:1 week
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We will assess weight loss via self-report after 1 week on diet #1
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1 week
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Weight loss- week 2
大体时间:1 week
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We will assess weight loss via self-report after 1 week on diet #2
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1 week
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Weight loss- week 3
大体时间:1 week
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We will assess weight loss via self-report after 1 week on diet #3
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1 week
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Energy intake-week 1
大体时间:6 weeks
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Energy (kcal) intake will be assessed after 1 week on diet #1
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6 weeks
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Energy intake- week 2
大体时间:6 weeks
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Energy (kcal) intake will be assessed after 1 week on diet #2
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6 weeks
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Energy intake- week 3
大体时间:6 weeks
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Energy (kcal) intake will be assessed after 1 week on diet #3
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6 weeks
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合作者和调查者
调查人员
- 首席研究员:Gabrielle Turner-McGrievy、University of South Carolina
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.