Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity. (IDEX1)
2026年8月3日 更新者：University Hospital, Clermont-Ferrand
The aim of the present study is to compare the effect of iso-energetic energy deficits induced by exercise or dietary restriction on energy intake and appetite feelings in adolescents with obesity
研究概览
地位
完全的
条件
详细说明
The present study will compare the nutritional response to an energy deficit of 400 kcal induced once by realisation of an acute exercise set at moderate intensity and once by a dietary restriction imposed at lunch (compared with a control condition). 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (CON); ii) one session with an exercise-induced energy deficit (Def-EX); iii) one session with an energy restriction-induced energy deficit (Def-EI).
Their ad libitum energy intake will be assessed during dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.
研究类型
介入性
注册 (实际的)
20
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
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Clermont-Ferrand、法国、63003
- Chu Clermont Ferrand
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-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
12年 至 17年 (孩子)
接受健康志愿者
是的
描述
Inclusion Criteria:
- BMI percentile > 97th percentile according to the french curves.
- ages 12-16 years old
- Signed consent form
- being registered in the national social security system
- no contraindication to physical activity
Exclusion Criteria:
- Previous surgical interventions that is considered as non-compatible with the study.
- Diabetes
- weight loss during the last 6 months
- cardiovascular disease or risks
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：肥胖青少年
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Control condition without exercise / rest condition.
The adolescents will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at dinner time.
Their food reward will be assessed before dinner.
Their appetite feelings will be assessed at regular intervals.
Condition with an exercise-induced energy deficit The adolescents will be asked to complete an acute exercise set at 65% of their capacities (cycling) during the afternoon, inducing an energy expenditure of 400 kcal.
Dinner will be served ad libitum.
Their food reward will be assessed before dinner.
Their appetite feelings will be assessed at regular intervals.
Condition with an energy-restriction energy deficit The adolescents will be asked to remain quiet during the whole day (no physical activity).
They will receive a calibrated breakfast reduced from 400 kcal compare to their CON and Def-EX conditions.
Dinner will be served ad libitum.
Their food reward will be assessed before dinner.
Their appetite feelings will be assessed at regular intervals.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Change from different intervention of energy intake measured during an ad libitum buffet meal (in kcal)
大体时间：day 1, day 8, day 15
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food intake will be measured ad libitum during a dinner buffet.
The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences.
Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software.
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day 1, day 8, day 15
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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饥饿感
大体时间：第 1 天、第 8 天、第 15 天
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曲线下的饥饿面积将通过一天的视觉模拟量表进行评估
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第 1 天、第 8 天、第 15 天
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Food reward
大体时间：day 1, day 8, day 15
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The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ)
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day 1, day 8, day 15
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
合作者
调查人员
- 首席研究员：Valérie JULIAN、University Hospital, Clermont-Ferrand
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Moore H, Pereira B, Fillon A, Miguet M, Masurier J, Beaulieu K, Finlayson G, Thivel D. The association between obesity severity and food reward in adolescents with obesity: a one-stage individual participant data meta-analysis. Eur J Nutr. 2024 Jun;63(4):1241-1255. doi: 10.1007/s00394-024-03348-4. Epub 2024 Feb 20.
- Fillon A, Pelissier L, Beaulieu K, Charlot K, Siroux J, Bagot S, Bailly M, Boscaro A, Finlayson G, Boirie Y, Duclos M, Isacco L, Pereira B, Julian V, Thivel D. Dietary- but not exercise-induced acute iso-energetic deficit result in short-term appetitive compensatory responses in adolescents with obesity. Appetite. 2023 Feb 1;181:106401. doi: 10.1016/j.appet.2022.106401. Epub 2022 Dec 5.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2021年8月28日
初级完成 (实际的)
2021年10月3日
研究完成 (实际的)
2021年10月3日
研究注册日期
首次提交
2021年1月27日
首先提交符合 QC 标准的
2021年2月1日
首次发布 (实际的)
2021年2月4日
研究记录更新
最后更新发布 (实际的)
2026年8月5日
上次提交的符合 QC 标准的更新
2026年8月3日
最后验证
2026年8月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.