Hair Regrowth Following Partial Thickness Removal of SSCIS
2026年9月2日 更新者：Naomi Lawrence、The Cooper Health System
Hair Regrowth Following Partial Thickness Stages in Mohs Micrographic Surgery of Squamous Cell Carcinoma in Situ: A Prospective Pilot Study
Participants are being approached to participate in this study because they are undergoing surgery for a skin cancer known as squamous cell carcinoma in situ (SCCIS) on the scalp.
Standard surgical techniques may remove deeper structures that contain hair follicles, which can result in permanent hair loss.
This study evaluates whether a modified surgical technique, known as partial thickness excision, can preserve hair growth and improve cosmetic outcomes.
Participation involves minimal risk beyond the standard risks of Mohs surgery.
If patients choose to participate, their surgery will be performed using this technique, and photographs will be taken over time to evaluate hair regrowth and healing.
研究概览
研究类型
介入性
注册 (估计的)
15
阶段
- 不适用
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
不
描述
Inclusion Criteria:
- Adults ≥ 18 years old
- Histologically confirmed SCCIS
- Lesions located in the hair-bearing scalp
- Ability to provide informed consent
Exclusion Criteria:
- Invasive, poorly differentiated, or high-risk SCC features (e.g., perineural invasion)
- Recurrent SCC at the same site
- Prior radiation therapy to the scalp
- Scarring alopecia or active inflammatory scalp disease at the treatment site
- Immunosuppression that, in the investigator's judgement, increases oncologic risk
- Use of topical minoxidil, oral minoxidil, finasteride, spironolactone, or other hair-growth promoting agents
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：预防
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Partial Thickness Excision
Participants will receive excision of their squamous cell carcinoma in situ of the scalp via partial thickness excision (removal of epidermal and superficial dermal tissue) in an effort to preserve hair follicles and hair growth potential.
|
Participants will receive excision of their squamous cell carcinoma in situ of the scalp via partial thickness excision (removal of epidermal and superficial dermal tissue) in an effort to preserve hair follicles and hair growth potential.
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Hair Growth measured clinically by hair density percentage compared to baseline photo
大体时间：3 and 6 months post-procedure.
|
To evaluate hair growth following partial thickness excision of SCCIS at 3 and 6 months post-procedure.
|
3 and 6 months post-procedure.
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Clearance of SCCIS measured by Mohs surgeons' interpretation of margins on surgical slides.
大体时间：Immediately following the final Mohs stage during the index procedure
|
To assess clinical and histologic clearance of SCCIS treated with partial-thickness excision.
|
Immediately following the final Mohs stage during the index procedure
|
|
Patient Satisfaction measured via patient satisfaction questionnaire
大体时间：3 and 6 months post-procedure
|
To evaluate patient-reported satisfaction with hair density and cosmetic outcome. "Are you satisfied with amount of hair//appearance of skin/result of treatment?" etc. on scale of 1-10. 1 being not satisfied and 10 being very satisfied/. |
3 and 6 months post-procedure
|
|
Complications
大体时间：2 weeks post-procedure, 3 months post-procedure, and 6 months post-procedure
|
To document wound-healing, complications, and the need for additional treatment.
|
2 weeks post-procedure, 3 months post-procedure, and 6 months post-procedure
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (估计的)
2026年9月1日
初级完成 (估计的)
2027年7月17日
研究完成 (估计的)
2028年7月17日
研究注册日期
首次提交
2026年8月4日
首先提交符合 QC 标准的
2026年9月2日
首次发布 (实际的)
2026年9月9日
研究记录更新
最后更新发布 (实际的)
2026年9月9日
上次提交的符合 QC 标准的更新
2026年9月2日
最后验证
2026年7月1日
更多信息
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